miconazole has been researched along with Acquired Immunodeficiency Syndrome in 4 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a randomized prospective study to compare the efficacy of oral miconazole and ketoconazole in the treatment of candida esophagitis in acquired immune deficiency syndrome (AIDS) patients in Haiti." | 5.06 | Treatment of candida esophagitis in AIDS patients. ( DeHovitz, J; Deschamps, MM; Johnson, WD; Pape, JW; Thomas, F; Verdier, RI, 1988) |
| "Cryptococcus neoformans strains from 26 individual patients with acquired immunodeficiency syndrome (AIDS) and three isolates from patients without AIDS were tested for their susceptibility to amphotericin B, flucytosine, ketoconazole, and miconazole nitrate." | 3.67 | In vitro susceptibility of Cryptococcus neoformans isolates from patients with acquired immunodeficiency syndrome. ( Bottone, EJ; Cronin, DC; Poon, M; Wormser, GP, 1988) |
| "Systemic fungal infections are life-threatening diseases that are occurring with increasing frequency, especially in immunocompromised patients." | 2.37 | Recent advances in the treatment of systemic fungal infections. ( Walsh, TJ, 1987) |
| "Two patients had acquired immunodeficiency syndrome (AIDS), one was human immunodeficiency virus (HIV)-positive, and the fourth refused HIV testing." | 1.29 | Spontaneous ulcerative keratitis in immunocompromised patients. ( Aristimuño, B; Hemady, RK; Nirankari, VS; Rodrigues, MM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aristimuño, B | 1 |
| Nirankari, VS | 1 |
| Hemady, RK | 1 |
| Rodrigues, MM | 1 |
| Walsh, TJ | 1 |
| Deschamps, MM | 1 |
| Pape, JW | 1 |
| Verdier, RI | 1 |
| DeHovitz, J | 1 |
| Thomas, F | 1 |
| Johnson, WD | 1 |
| Poon, M | 1 |
| Cronin, DC | 1 |
| Wormser, GP | 1 |
| Bottone, EJ | 1 |
1 review available for miconazole and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Recent advances in the treatment of systemic fungal infections.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Drug Resistance, Microbial; D | 1987 |
1 trial available for miconazole and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Treatment of candida esophagitis in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Candidiasis; Clinical Trials as Top | 1988 |
2 other studies available for miconazole and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Spontaneous ulcerative keratitis in immunocompromised patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Adult; Amikacin; Amphotericin B; Candid | 1993 |
In vitro susceptibility of Cryptococcus neoformans isolates from patients with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Cryptococcus; Cryptococcus ne | 1988 |