micafungin and Escherichia-coli-Infections

micafungin has been researched along with Escherichia-coli-Infections* in 1 studies

Other Studies

1 other study(ies) available for micafungin and Escherichia-coli-Infections

Article	Year
Sporopachydermia cereana fungaemia in refractory leukaemia presenting as breakthrough infection during micafungin therapy. Infection, 2013, Volume: 41, Issue:3 The Sporopachydermia cereana species lives in decaying stems of cactus and is exceptionally rare as a human pathogen. A 57-year-old man with therapy-refractory acute promyelocytic leukaemia developed severe neutropaenia. After about 3 weeks of micafungin used as prophylaxis, he developed high fever, multiple pulmonary nodular infiltrates and a painful leg lesion. Blood culture yielded a yeast which was not identified by the Vitek 2 system. On ITS1-5.8S-ITS2 gene sequencing, the isolate was identified as S. cereana. Antifungal sensitivity by the Etest showed that the minimum inhibitory concentration for fluconazole was 0.75 μg/mL, and for anidulafungin, it was >32 μg/mL. He responded to liposomal amphotericin B but later died of Escherichia coli septicaemia. There were no cactus plants in the vicinity, suggesting that S. cereana might have alternative habitats. Topics: Antifungal Agents; Chemoprevention; DNA, Fungal; DNA, Ribosomal; DNA, Ribosomal Spacer; Echinocandins; Escherichia coli Infections; Fatal Outcome; Fungemia; Humans; Immunocompromised Host; Leukemia, Promyelocytic, Acute; Lipopeptides; Male; Micafungin; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Opportunistic Infections; Radiography, Thoracic; Saccharomycetales; Sepsis; Sequence Analysis, DNA; Skin; Tomography, X-Ray Computed	2013

Article

Year

Sporopachydermia cereana fungaemia in refractory leukaemia presenting as breakthrough infection during micafungin therapy.

Infection, 2013, Volume: 41, Issue:3

The Sporopachydermia cereana species lives in decaying stems of cactus and is exceptionally rare as a human pathogen. A 57-year-old man with therapy-refractory acute promyelocytic leukaemia developed severe neutropaenia. After about 3 weeks of micafungin used as prophylaxis, he developed high fever, multiple pulmonary nodular infiltrates and a painful leg lesion. Blood culture yielded a yeast which was not identified by the Vitek 2 system. On ITS1-5.8S-ITS2 gene sequencing, the isolate was identified as S. cereana. Antifungal sensitivity by the Etest showed that the minimum inhibitory concentration for fluconazole was 0.75 μg/mL, and for anidulafungin, it was >32 μg/mL. He responded to liposomal amphotericin B but later died of Escherichia coli septicaemia. There were no cactus plants in the vicinity, suggesting that S. cereana might have alternative habitats.

Topics: Antifungal Agents; Chemoprevention; DNA, Fungal; DNA, Ribosomal; DNA, Ribosomal Spacer; Echinocandins; Escherichia coli Infections; Fatal Outcome; Fungemia; Humans; Immunocompromised Host; Leukemia, Promyelocytic, Acute; Lipopeptides; Male; Micafungin; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Opportunistic Infections; Radiography, Thoracic; Saccharomycetales; Sepsis; Sequence Analysis, DNA; Skin; Tomography, X-Ray Computed

2013