micafungin and Anemia--Aplastic

micafungin has been researched along with Anemia--Aplastic* in 2 studies

Other Studies

2 other study(ies) available for micafungin and Anemia--Aplastic

Article	Year
Micafungin as antifungal prophylaxis in non-transplanted haemotological patients. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2020, Volume: 33, Issue:1 Fungal infections are a major cause of morbidity and mortality in the haematological patients. These infections are mainly due to Candida spp. and Aspergillus spp. Mortality by these infections is high, but rates have descended in the latest series due to better antifungal agents. Echinocan-dins are, in vitro, very active against Candida and Aspergillus spp. The objective of the study is to analyse the efﬁcacy and safety of micafungin in the antifungal prophylaxis of haema-tological patients on chemotherapy.. A multicentre, observational retrospective study was performed in 7 Haematology Depart-ments in Spain. Patients admitted to these departments with chemotherapy or immunosuppressive treatment, and who had received antifungal prophylaxis with micafungin between 1 January 2009 and 31 December 2014 were included.. There were 5 cases of probable or proven fun-gal infection (4.8%) according to the 2008 EORTC criteria: 2 proven, 3 probable. The types of fungal infection were 3 as-pergillosis and 2 candidiasis. There were no drop-outs from the prophylaxis with micafungin due to toxicity.. Micafungin is an antifungal agent which, used in prophylaxis, has demonstrated good efﬁcacy and an excellent toxicity proﬁle, making it an apparently interesting option in patients requiring antifungal prophylaxis during their hospitalisation episode. Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antifungal Agents; Aspergillosis; Candidiasis; Female; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Micafungin; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Young Adult	2020
Invasive sino-orbital mycosis in an aplastic anemia patient caused by Neosartorya laciniosa. Journal of clinical microbiology, 2013, Volume: 51, Issue:4 We report the first case of Neosartorya laciniosa invasive sinusitis involving the orbit in an immunocompromised male with aplastic anemia. Treatment included surgical debridement with enucleation of the eye and combination voriconazole and micafungin therapy followed by voriconazole alone. The fungus was identified using sequencing of partial benA and calmodulin genes. Topics: Aged; Anemia, Aplastic; Antifungal Agents; Debridement; DNA, Fungal; Echinocandins; Eye Enucleation; Fungal Proteins; Humans; Lipopeptides; Male; Micafungin; Molecular Sequence Data; Mycoses; Neosartorya; Orbital Diseases; Phylogeny; Pyrimidines; Sequence Analysis, DNA; Sequence Homology; Sinusitis; Triazoles; Voriconazole	2013

Article

Year

Micafungin as antifungal prophylaxis in non-transplanted haemotological patients.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2020, Volume: 33, Issue:1

Fungal infections are a major cause of morbidity and mortality in the haematological patients. These infections are mainly due to Candida spp. and Aspergillus spp. Mortality by these infections is high, but rates have descended in the latest series due to better antifungal agents. Echinocan-dins are, in vitro, very active against Candida and Aspergillus spp. The objective of the study is to analyse the efﬁcacy and safety of micafungin in the antifungal prophylaxis of haema-tological patients on chemotherapy.. A multicentre, observational retrospective study was performed in 7 Haematology Depart-ments in Spain. Patients admitted to these departments with chemotherapy or immunosuppressive treatment, and who had received antifungal prophylaxis with micafungin between 1 January 2009 and 31 December 2014 were included.. There were 5 cases of probable or proven fun-gal infection (4.8%) according to the 2008 EORTC criteria: 2 proven, 3 probable. The types of fungal infection were 3 as-pergillosis and 2 candidiasis. There were no drop-outs from the prophylaxis with micafungin due to toxicity.. Micafungin is an antifungal agent which, used in prophylaxis, has demonstrated good efﬁcacy and an excellent toxicity proﬁle, making it an apparently interesting option in patients requiring antifungal prophylaxis during their hospitalisation episode.

Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antifungal Agents; Aspergillosis; Candidiasis; Female; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Micafungin; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Young Adult

2020

Invasive sino-orbital mycosis in an aplastic anemia patient caused by Neosartorya laciniosa.

Journal of clinical microbiology, 2013, Volume: 51, Issue:4

We report the first case of Neosartorya laciniosa invasive sinusitis involving the orbit in an immunocompromised male with aplastic anemia. Treatment included surgical debridement with enucleation of the eye and combination voriconazole and micafungin therapy followed by voriconazole alone. The fungus was identified using sequencing of partial benA and calmodulin genes.

Topics: Aged; Anemia, Aplastic; Antifungal Agents; Debridement; DNA, Fungal; Echinocandins; Eye Enucleation; Fungal Proteins; Humans; Lipopeptides; Male; Micafungin; Molecular Sequence Data; Mycoses; Neosartorya; Orbital Diseases; Phylogeny; Pyrimidines; Sequence Analysis, DNA; Sequence Homology; Sinusitis; Triazoles; Voriconazole

2013