mibefradil has been researched along with Cardiac Failure in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (65.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernink, PJ; Blanksma, PK; Knol, HR; Lie, KI; Muntinga, HJ; Niemeyer, MG; van den Berg, F; van der Vring, JA; van der Wall, EE | 1 |
| Levine, TB | 1 |
| Massie, BM | 1 |
| Katz, S | 1 |
| Clozel, JP; Ertel, EA; Ertel, SI | 1 |
| Hermsmeyer, K | 1 |
| Mulder, P; Richard, V; Thuillez, C | 1 |
| Borzak, S; Goldstein, S; Sabbah, HN; Shimoyama, H; Tanimura, M | 1 |
| Pool, PE | 1 |
| van Zwieten, PA | 1 |
| Chung, O; Daemen, MJ; Illner, S; Jänichen, G; Rossius, B; Sandmann, S; Spitznagel, H; Unger, T; Xia, QG | 1 |
| Meissner, A; Min, JY; Sandmann, S; Unger, T | 1 |
| Ammon, S; Bernink, PJ; Caspi, A; Elkayam, U; Geltman, EM; Ghali, JK; Giles, TD; Greenberg, B; Levine, TB; Lindberg, E; Marmor, A; McKenna, WJ; Reisin, LH | 1 |
| Brouwer, J; Crijns, HJ; de Kam, PJ; Haaksma, J; Tjeerdsma, G; van Veldhuisen, DJ | 1 |
| Bohle, RM; Dreyer, T; Sandmann, S; Unger, T | 1 |
| Gattis, W; O'Connor, CM | 1 |
| Claas, R; Cleutjens, JP; Daemen, MJ; Sandmann, S; Unger, T | 1 |
| Dumont, L; Jasmin, G; Massicotte, J; Villame, J | 1 |
| Poole-Wilson, PA; van Veldhuisen, DJ | 1 |
| Clozel, JP; Osterrieder, W; Véniant, M | 1 |
7 review(s) available for mibefradil and Cardiac Failure
| Article | Year |
|---|---|
Mibefradil: a selective T-type calcium antagonist.
Topics: Angina Pectoris; Animals; Benzimidazoles; Calcium Channel Blockers; Heart Failure; Humans; Hypertension; Mibefradil; Structure-Activity Relationship; Tetrahydronaphthalenes | 1997 |
Safety of calcium antagonists in patients with congestive heart failure.
Topics: Benzimidazoles; Calcium Channel Blockers; Clinical Trials as Topic; Heart; Heart Failure; Hemodynamics; Humans; Mibefradil; Survival Analysis; Tetrahydronaphthalenes | 1997 |
Discovery and main pharmacological properties of mibefradil (Ro 40-5967), the first selective T-type calcium channel blocker.
Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Heart Failure; Heart Rate; Humans; Kidney; Mibefradil; Tetrahydronaphthalenes; Vasodilator Agents | 1997 |
Role of T channels in cardiovascular function.
Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Cardiovascular Physiological Phenomena; Heart; Heart Failure; Humans; Mibefradil; Myocardial Contraction; Myocardium; Tetrahydronaphthalenes | 1998 |
Neurohormonal activation in the treatment of congestive heart failure: basis for new treatments?
Topics: Benzimidazoles; Calcium Channel Blockers; Heart Failure; Hormones; Humans; Mibefradil; Neurotransmitter Agents; Tetrahydronaphthalenes | 1998 |
[Calcium antagonists in the treatment of heart failure. Re-evaluation of therapeutic strategies].
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Evidence-Based Medicine; Heart Failure; Humans; Mibefradil; Ventricular Dysfunction, Left | 2000 |
The underreporting of results and possible mechanisms of 'negative' drug trials in patients with chronic heart failure.
Topics: Bosentan; Cardiovascular Agents; Deoxyepinephrine; Heart Failure; Humans; Imidazoles; Mibefradil; Pyrazines; Quinolines; Sulfonamides; Xamoterol | 2001 |
4 trial(s) available for mibefradil and Cardiac Failure
| Article | Year |
|---|---|
Effect of mibefradil on left ventricular diastolic function in patients with congestive heart failure.
Topics: Adult; Aged; Benzimidazoles; Calcium Channel Blockers; Diastole; Double-Blind Method; Female; Heart Failure; Humans; Male; Mibefradil; Middle Aged; Tetrahydronaphthalenes; Ventricular Function, Left | 1996 |
The design of the Mortality Assessment in Congestive Heart Failure Trial (MACH-1, mibefradil).
Topics: Benzimidazoles; Calcium Channel Blockers; Canada; Double-Blind Method; Europe; Female; Heart Failure; Humans; Israel; Male; Mibefradil; Research Design; Tetrahydronaphthalenes; United States | 1997 |
Effect of mibefradil, a T-type calcium channel blocker, on morbidity and mortality in moderate to severe congestive heart failure: the MACH-1 study. Mortality Assessment in Congestive Heart Failure Trial.
Topics: Aged; Calcium Channel Blockers; Calcium Channels, T-Type; Double-Blind Method; Exercise Test; Female; Heart Failure; Humans; Male; Mibefradil; Middle Aged; Morbidity; Mortality; Physical Endurance | 2000 |
Effect of mibefradil on heart rate variability in patients with chronic heart failure.
Topics: Autonomic Nervous System; Calcium Channel Blockers; Case-Control Studies; Female; Heart Failure; Heart Rate; Humans; Longitudinal Studies; Male; Mibefradil; Middle Aged; Netherlands; Placebos | 2000 |
9 other study(ies) available for mibefradil and Cardiac Failure
| Article | Year |
|---|---|
Different effects of calcium antagonists in a rat model of heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Calcium Channel Blockers; Catecholamines; Chronic Disease; Cilazapril; Heart Failure; Heart Ventricles; Hemodynamics; Male; Mibefradil; Myocardial Contraction; Random Allocation; Rats; Rats, Wistar; Renin; Survival Rate; Tetrahydronaphthalenes | 1998 |
Short-term hemodynamic effects of mibefradil in dogs with chronic heart failure: comparison with diltiazem.
Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Diltiazem; Dogs; Heart Failure; Hemodynamics; Mibefradil; Tetrahydronaphthalenes | 1998 |
Cardioprotective activity of mibefradil.
Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Heart Failure; Hemodynamics; Humans; Mibefradil; Myocardial Infarction; Rats; Recurrence; Tetrahydronaphthalenes; Vasodilator Agents | 1998 |
Effects of the calcium channel antagonist mibefradil on haemodynamic and morphological parameters in myocardial infarction-induced cardiac failure in rats.
Topics: Analysis of Variance; Animals; Benzimidazoles; Calcium Channel Blockers; Drug Administration Schedule; Heart Failure; Hemodynamics; Male; Methoxamine; Mibefradil; Myocardial Contraction; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Wistar; Tetrahydronaphthalenes; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Effects of the calcium channel antagonist mibefradil on haemodynamic parameters and myocardial Ca(2+)-handling in infarct-induced heart failure in rats.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Heart Failure; Heart Rate; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Mibefradil; Myocardial Contraction; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Ventricular Pressure | 1999 |
The T-type calcium channel blocker mibefradil reduced interstitial and perivascular fibrosis and improved hemodynamic parameters in myocardial infarction-induced cardiac failure in rats.
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Fibrosis; Heart; Heart Failure; Hemodynamics; Male; Mibefradil; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Wistar; Ventricular Remodeling | 2000 |
Calcium channel blockade limits cardiac remodeling and improves cardiac function in myocardial infarction-induced heart failure in rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Heart Failure; Hemodynamics; Hypertrophy, Left Ventricular; Male; Mibefradil; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Ventricular Remodeling; Verapamil | 2001 |
Effects of mibefradil, a T- and L-type calcium channel blocker, on cardiac remodeling in the UM-X7.1 cardiomyopathic hamster.
Topics: Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Capillaries; Cardiomyopathies; Cricetinae; Heart Failure; Mesocricetus; Mibefradil; Myocardium; Organ Size; Ventricular Remodeling | 2001 |
The structurally novel Ca2+ channel blocker Ro 40-5967, which binds to the [3H] desmethoxyverapamil receptor, is devoid of the negative inotropic effects of verapamil in normal and failing rat hearts.
Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Coronary Circulation; Depression, Chemical; Dose-Response Relationship, Drug; Female; Heart; Heart Failure; Hemodynamics; Male; Mibefradil; Myocardial Contraction; Myocardial Infarction; Rats; Rats, Inbred WKY; Receptors, Nicotinic; Tetrahydronaphthalenes; Tritium; Verapamil | 1990 |