Page last updated: 2024-08-24

mibefradil and Blood Pressure, High

mibefradil has been researched along with Blood Pressure, High in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	59 (85.51)	18.2507
2000's	10 (14.49)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ball, CJ; Beltrame, JF; Saint, DA; Turner, SP; Wilson, DP	1
Godfraind, T	1
Buranakitcharoen, P; Sermswan, A; Sukontasarn, A; Suthichaiyakul, T; Uboldejpracharak, Y	1
Hayashi, K; Homma, K; Kanda, T; Kumagai, H; Okubo, K; Ozawa, Y; Saruta, T; Takamatsu, I; Tatematsu, S; Wakino, S	1
Ekholm, M; Hjemdahl, P; Kahan, T; Lindqvist, M; Melcher, A	1
Black, N; Dhamija, S; Kowala, MC; Liachenko, S; Madore, S; Major, TC; Morenko, B; Okerberg, C; Sobocinski, G; Tinholt, P	1
Boulanger, CM; Clozel, JP; Desta, B; Vanhoutte, PM	1
Bernink, PJ; Kobrin, I; Prager, G; Schelling, A	1
Clozel, JP; Clozel, M; Gonzales, MF; Hess, P; Heudes, D; Karam, H; Löffler, BM	1
Bruneval, P; Clozel, JP; Clozel, M; Gonzales, MF; Heudes, D; Karam, H; Löffler, BM	1
Li, JS; Schiffrin, EL	2
Bühler, FR; Clozel, JP; Iberg, N; Schmitt, R	1
Clozel, JP; Fornes, P; Richer, C; Vacher, E	1
Crome, R; Elliott, HL; Glen, SK; MacMahon, M; Meredith, PA; Petrie, JR; Reid, JL	1
Archambault, F; Dalle Ave, S; Lacourcière, Y; Lefebvre, J; Lindberg, E; Poirier, L; Ward, C	1
Chrysant, SG; Jain, A; Korrin, I; Massie, BM; Weir, M; Weiss, R	1
Bhanot, S; Hicke, A; McNeill, JH; Verma, S	1
Abernethy, DR; Kobrin, I; Levine, BS; Oparil, S; Reif, MC; Shepherd, AM	1
Bernink, PJ; Kantola, IM; Kobrin, I; Ribeiro, AB; Schelling, A; Viskoper, RJ; Wilkins, MR	1
Carney, S; Kallwellis, R; Kobrin, I; Mion, D; Ribeiro, A; Viskoper, RJ; Wing, L; Zimlichman, R	1
Nakagawa, M; Sasaki, S	1
Bernink, P; Bursztyn, M; Carney, S; Kobrin, I; Oparil, S	1
Kobrin, I; Lacourcière, Y; Massie, BM; Viskoper, R; Woittiez, A	1
Charlon, V; Kobrin, I; Lindberg, E; Pordy, R	1
Bursztyn, M; Kadr, H; Kobrin, I; Martina, B; Oigman, W; Talberg, J; Tilvis, R	1
Brogden, RN; Markham, A	1
Giles, TD	1
Massie, BM	1
Pitt, B	1
Hermsmeyer, K; Minshall, R; Mishra, S; Miyagawa, K	1
Habib, G	1
Meredith, PA	1
Kobrin, I	1
Conlin, PR; Williams, GH	1
Bailey, R; Huysmans, FT; Kobrin, I; Mion Júnior, D; Robson, RA; Villa, G; Woittiez, AJ	1
Koen, R; Lacolley, P; Levy, BI; Poitevin, P	1
Waeber, B	1
Ritz, E; Wagner, J	1
Oparil, S	1
Lynn, MM	1
Billups, SJ; Carter, BL	1
Cifkova, R; Höglund, C; Lindberg, E; Mimran, A; Tenczer, J; Watt, A; Wilkins, MR	1
de Chatel, R; Houwing, N; Weidekamm, E; Welker, HA	1
Pirrelli, A; Vulpis, V	1
Bock, A; Peters, J; Spoendlin, M; Thiel, G; Welker, H	1
Glasser, SP	1
SoRelle, R	1
Gallino, A; Giostra, E; Krähenbühl, S; Menafoglio, A	1
Welker, HA	1
Pordy, R; Woittiez, A	1
Battegay, E; Drewe, J; Frach, B; Gasser, P; Martina, B; Surber, C	1
Bart, T; Battegay, EJ; Frach, B; Lorz, W; Martina, B	1
Frohlich, ED; Nakamura, Y; Ono, H	1
Balfagón, G; Encabo, A; Ferrer, M; Manso, AM; Marín, J; Salaices, M	1
Bruneval, P; Clozel, JP; Gonzalez, MF; Karam, H; Ménard, J	1
Bruneval, P; Duong Van Huyen, JP; Heudes, D; Qiu, C; Roeckel, A; Roux, S	1
Edoute, Y; Roguin, A	1
Esler, MD; Kamen, PW; Krum, H; Lim, S; Pellizzer, AM	1
Gläser, S; Kleber, FX; Opitz, C; Steinbach, M; Wruck, U	1
Duggan, JA; Tabrizchi, R	1
Riley, J; Shakir, SA; Wilton, LV	1
Belz, GG; Feifel, U; Halabi, A; Kirch, W; Kleinbloesem, CH; Pozenel, H; Schmitt, R; Schroeter, V; Welker, HA; Woittiez, AJ	1
Clozel, JP; Hefti, F; Osterrieder, W	1

Reviews

15 review(s) available for mibefradil and Blood Pressure, High

Article	Year
[Calcium channel blocker for therapy of patients with hypertension]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:8 Topics: Benzimidazoles; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes; Thiazoles	1997
Mibefradil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of hypertension and angina pectoris. Drugs, 1997, Volume: 54, Issue:5 Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Half-Life; Hemodynamics; Humans; Hypertension; Mibefradil; Molecular Structure; Myocardial Contraction; Tetrahydronaphthalenes	1997
Mibefradil (posicor). Comprehensive therapy, 1997, Volume: 23, Issue:11 Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes; Treatment Outcome	1997
Mibefradil: a selective T-type calcium antagonist. The American journal of cardiology, 1997, Nov-06, Volume: 80, Issue:9A Topics: Angina Pectoris; Animals; Benzimidazoles; Calcium Channel Blockers; Heart Failure; Humans; Hypertension; Mibefradil; Structure-Activity Relationship; Tetrahydronaphthalenes	1997
Diversity of calcium antagonists. Clinical therapeutics, 1997, Volume: 19 Suppl A Topics: Angina Pectoris; Arteriosclerosis; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Kidney Failure, Chronic; Mibefradil; Nifedipine; Tetrahydronaphthalenes; Verapamil	1997
Physiologic and pathophysiologic relevance of T-type calcium-ion channels: potential indications for T-type calcium antagonists. Clinical therapeutics, 1997, Volume: 19 Suppl A Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Cardiovascular Physiological Phenomena; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1997
Reappraisal of the importance of heart rate as a risk factor for cardiovascular morbidity and mortality. Clinical therapeutics, 1997, Volume: 19 Suppl A Topics: Adrenergic beta-Antagonists; Benzimidazoles; Calcium Channel Blockers; Cardiovascular Diseases; Heart Rate; Humans; Hypertension; Mibefradil; Myocardial Infarction; Risk Factors; Tetrahydronaphthalenes	1997
Clinical relevance of optimal pharmacokinetics in the treatment of hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1997, Volume: 15, Issue:5 Topics: Antihypertensive Agents; Benzimidazoles; Dose-Response Relationship, Drug; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1997
Use of calcium channel blockers in hypertension. Advances in internal medicine, 1998, Volume: 43 Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Heart Diseases; Humans; Hypertension; Longitudinal Studies; Mibefradil; Nifedipine; Public Health; Randomized Controlled Trials as Topic; Risk Factors; Tetrahydronaphthalenes; Vasodilator Agents; Verapamil	1998
Potential cardioprotective effect of mibefradil in the long-term treatment of hypertension. Cardiology, 1998, Volume: 89 Suppl 1 Topics: Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Coronary Disease; Drug Interactions; Follow-Up Studies; Heart Rate; Humans; Hypertension; Mibefradil; Safety; Tetrahydronaphthalenes; Treatment Outcome	1998
Mibefradil, a T-channel-selective calcium antagonist: clinical trials in hypertension. American journal of hypertension, 1998, Volume: 11, Issue:4 Pt 3 Topics: Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Heart Rate; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1998
Mibefradil: a new class of calcium-channel antagonists. The Annals of pharmacotherapy, 1998, Volume: 32, Issue:6 Topics: Aged; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Mibefradil; Tetrahydronaphthalenes	1998
[Evolution of antihypertensive therapy with calcium antagonists: the new molecules]. Cardiologia (Rome, Italy), 1998, Volume: 43, Issue:4 Topics: Antihypertensive Agents; Benzimidazoles; Calcium Channel Blockers; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1998
The relevance of T-type calcium antagonists: a profile of mibefradil. Journal of clinical pharmacology, 1998, Volume: 38, Issue:8 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1998
[Mibefradil--a T-type calcium channel blocker]. Harefuah, 1999, Jan-15, Volume: 136, Issue:2 Topics: Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, T-Type; Humans; Hypertension; Mibefradil	1999

Trials

22 trial(s) available for mibefradil and Blood Pressure, High

Article	Year
Long-term calcium antagonist treatment of human hypertension with mibefradil or amlodipine increases sympathetic nerve activity. Journal of hypertension, 2007, Volume: 25, Issue:1 Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cross-Over Studies; Double-Blind Method; Female; Heart; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Norepinephrine; Sympathetic Nervous System; Time Factors; Ultrasonography	2007
Antihypertensive properties of the novel calcium antagonist mibefradil (Ro 40-5967): a new generation of calcium antagonists? Mibefradil International Study Group. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:3 Pt 1 Topics: Adolescent; Adult; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Tetrahydronaphthalenes	1996
Haemodynamics, cardiac conduction and pharmacokinetics of mibefradil (Ro 40-5967), a novel calcium antagonist. Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 2 Topics: Adolescent; Adult; Aged; Benzimidazoles; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Heart Conduction System; Hemodynamics; Humans; Hypertension; Male; Mibefradil; Middle Aged; Tetrahydronaphthalenes	1995
The antihypertensive efficacy of the novel calcium antagonist mibefradil in comparison with nifedipine GITS in moderate to severe hypertensives with ambulatory hypertension. American journal of hypertension, 1997, Volume: 10, Issue:2 Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Body Weight; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Lisinopril; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1997
Antihypertensive effects of mibefradil: a double-blind comparison with diltiazem CD. Clinical cardiology, 1997, Volume: 20, Issue:6 Topics: Adult; Aged; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Linear Models; Male; Mibefradil; Middle Aged; Multivariate Analysis; Tetrahydronaphthalenes	1997
Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertension. American journal of hypertension, 1997, Volume: 10, Issue:7 Pt 1 Topics: Adolescent; Adult; Aged; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Tetrahydronaphthalenes	1997
A randomised, double-blind trial comparing mibefradil and amlodipine: two long-acting calcium antagonists with similar efficacy but different tolerability profiles. Mibefradil International Study Group. Journal of human hypertension, 1997, Volume: 11, Issue:6 Topics: Adult; Aged; Amlodipine; Benzimidazoles; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Mibefradil; Middle Aged; Tetrahydronaphthalenes	1997
The addition of mibefradil to chronic hydrochlorothiazide therapy in hypertensive patients is associated with a significant antihypertensive effect. Journal of human hypertension, 1997, Volume: 11, Issue:7 Topics: Adult; Aged; Benzimidazoles; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Mibefradil; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrahydronaphthalenes	1997
Antihypertensive effects of mibefradil in the treatment of mild-to-moderate systemic hypertension. The American journal of cardiology, 1997, Aug-21, Volume: 80, Issue:4B Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Tetrahydronaphthalenes	1997
Mibefradil in the treatment of systemic hypertension: comparative studies with other calcium antagonists. The American journal of cardiology, 1997, Aug-21, Volume: 80, Issue:4B Topics: Adult; Aged; Amlodipine; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Edema; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Leg; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1997
Safety of mibefradil, a new once-a-day, selective T-type calcium channel antagonist. The American journal of cardiology, 1997, Aug-21, Volume: 80, Issue:4B Topics: Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Chronic Disease; Drug Administration Schedule; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1997
Mibefradil, a novel calcium antagonist, in elderly patients with hypertension: favorable hemodynamics and pharmacokinetics. American heart journal, 1997, Volume: 134, Issue:2 Pt 1 Topics: Aged; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Mibefradil; Tetrahydronaphthalenes	1997
Differential properties of mibefradil in hypertension and angina. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1997, Volume: 15, Issue:5 Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Heart Rate; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes	1997
A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension. Clinical nephrology, 1998, Volume: 49, Issue:3 Topics: Adult; Aged; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1998
A comparison of the effects of mibefradil and atenolol on regression of left ventricular hypertrophy in hypertensive patients. Cardiology, 1998, Volume: 89, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Antihypertensive Agents; Atenolol; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Mibefradil; Tetrahydronaphthalenes	1998
Pharmacokinetics and pharmacodynamics of mibefradil in hypertensive patients with varying degrees of renal insufficiency. Pharmacology, 1998, Volume: 56, Issue:6 Topics: Adolescent; Adult; Aged; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Renal Dialysis; Renal Insufficiency; Tetrahydronaphthalenes	1998
Single- and multiple-dose mibefradil pharmacokinetics in normal and hypertensive subjects. The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:9 Topics: Administration, Oral; Adult; Area Under Curve; Benzimidazoles; Biological Availability; Calcium Channel Blockers; Cross-Over Studies; Drug Administration Schedule; Half-Life; Humans; Hypertension; Infusions, Intravenous; Male; Metabolic Clearance Rate; Mibefradil; Reference Values; Tetrahydronaphthalenes; Therapeutic Equivalency	1998
Steady-state trough plasma mibefradil concentrations and correlation to blood pressure response in hypertensive patients with chronic renal disease. International journal of clinical pharmacology research, 1998, Volume: 18, Issue:3 Topics: Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Kidney Failure, Chronic; Linear Models; Mibefradil; Nifedipine; Tetrahydronaphthalenes	1998
Capillary blood cell velocity in finger nailfold: effect of enalapril and mibefradil in patients with mild to moderate hypertension. Microvascular research, 1999, Volume: 57, Issue:2 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Capillaries; Enalapril; Female; Humans; Hypertension; Male; Mibefradil; Middle Aged; Nails; Tetrahydronaphthalenes	1999
The effects of mibefradil and enalapril on 24-hour blood pressure control and left ventricular mass in patients with mild to moderate hypertension: double-blind, randomized trial. Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:4 Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Mibefradil; Middle Aged; Prospective Studies; Tetrahydronaphthalenes; Vasodilator Agents; Ventricular Function, Left	1999
Comparative effects of mibefradil and nifedipine gastrointestinal transport system on autonomic function in patients with mild to moderate essential hypertension. Journal of hypertension, 2001, Volume: 19, Issue:2 Topics: Autonomic Nervous System; Calcium Channel Blockers; Double-Blind Method; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Male; Mibefradil; Middle Aged; Nifedipine; Norepinephrine; Pressoreceptors; Prospective Studies	2001
Hemodynamic and humoral effects of the novel calcium antagonist Ro 40-5967 in patients with hypertension. Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:3 Topics: Aldosterone; Benzimidazoles; Calcium Channel Blockers; Catecholamines; Drug Administration Schedule; Drug Tolerance; Female; Hemodynamics; Humans; Hypertension; Male; Mibefradil; Middle Aged; Placebos; Renin; Tetrahydronaphthalenes	1992

Other Studies

32 other study(ies) available for mibefradil and Blood Pressure, High

Article	Year
Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:4 Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Humans; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Organophosphorus Compounds; Potassium Chloride; Rats; Rats, Sprague-Dawley; Subcutaneous Fat; Vasoconstriction; Verapamil	2009
Is combined L- and T-channel blockade better than L-channel blockade in therapy? Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1 Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Drug Synergism; Humans; Hypertension; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Rats; Vasoconstriction; Verapamil	2009
Blood pressure response to antihypertensive agents related to baseline blood pressure. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, Volume: 85, Issue:10 Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Mibefradil; Middle Aged; Retrospective Studies; Severity of Illness Index; Treatment Outcome	2002
Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats--studies in the isolated perfused hydronephrotic kidney. The Keio journal of medicine, 2005, Volume: 54, Issue:2 Topics: Angiotensin II; Animals; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydronephrosis; Hypertension; Kidney; Male; Mibefradil; Microcirculation; Nifedipine; Perfusion; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Staurosporine; Thapsigargin; Vasodilator Agents	2005
The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3 Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Edema; Femoral Artery; Hindlimb; Hypertension; Magnetic Resonance Imaging; Mibefradil; Muscle, Skeletal; Nifedipine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; RNA, Messenger	2008
Chronic treatment with the CA2+ channel inhibitor RO 40-5967 potentiates endothelium-dependent relaxations in the aorta of the hypertensive salt sensitive Dahl rat. Blood pressure, 1994, Volume: 3, Issue:3 Topics: Animals; Aorta; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Hypertension; Male; Mibefradil; Rats; Rats, Mutant Strains; Reference Values; Sodium Chloride; Tetrahydronaphthalenes; Time Factors; Vasodilation; Vasodilator Agents	1994
Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats. Cardiovascular research, 1996, Volume: 31, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Bosentan; Calcium Channel Blockers; Cardiomegaly; Collagen; Coronary Circulation; Desoxycorticosterone; Enalapril; Endothelin Receptor Antagonists; Fibrosis; Hypertension; Male; Mibefradil; Myocardium; Perfusion; Rats; Rats, Wistar; Sulfonamides; Tetrahydronaphthalenes	1996
Endothelin antagonism in end-organ damage of spontaneously hypertensive rats. Comparison with angiotensin-converting enzyme inhibition and calcium antagonism. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Benzimidazoles; Body Weight; Bosentan; Calcium Channel Blockers; Cardiomegaly; Coronary Circulation; Enalapril; Endothelins; Fibrosis; Heart Ventricles; Hemodynamics; Hormones; Hypertension; Kidney; Mibefradil; Myocardium; Rats; Rats, Inbred SHR; Sulfonamides; Tetrahydronaphthalenes	1996
Effect of calcium channel blockade or angiotensin-converting enzyme inhibition on structure of coronary, renal, and other small arteries in spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Cilazapril; Coronary Vessels; Femoral Artery; Heart; Hypertension; Mesenteric Arteries; Mibefradil; Microcirculation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Renin; Tetrahydronaphthalenes	1996
Prevention of neointima formation by mibefradil after vascular injury in rats: comparison with ACE inhibition. Cardiovascular drugs and therapy, 1996, Volume: 10, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Calcium Channel Blockers; Carotid Arteries; Carotid Artery Injuries; Carotid Stenosis; Cell Division; Cell Movement; Cilazapril; Hypertension; In Vitro Techniques; Male; Mibefradil; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrahydronaphthalenes; Time Factors; Tunica Intima	1996
Mibefradil, a selective calcium T-channel blocker, in stroke-prone spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:5 Topics: Animals; Benzimidazoles; Blood Pressure; Body Weight; Calcium Channel Blockers; Cerebral Arteries; Cerebrovascular Disorders; Heart Rate; Hypertension; In Vitro Techniques; Male; Mibefradil; Rats; Rats, Inbred SHR; Tetrahydronaphthalenes	1996
Effect of short-term treatment of SHR with the novel calcium channel antagonist mibefradil on function of small arteries. American journal of hypertension, 1997, Volume: 10, Issue:1 Topics: Animals; Arteries; Benzimidazoles; Calcium Channel Blockers; Hypertension; Mibefradil; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrahydronaphthalenes; Vascular Resistance; Vasodilator Agents	1997
[Mibefradil opens up a new class of calcium antagonists. Glasgow, 23 June 1996]. Deutsche medizinische Wochenschrift (1946), 1996, Sep-27, Volume: 121, Issue:39 Suppl Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1996
Chronic T-type Ca2+ channel blockade with mibefradil in hyperinsulinemic, insulin-resistant and hypertensive rats. Cardiovascular research, 1997, Volume: 34, Issue:1 Topics: Animals; Benzimidazoles; Blood Glucose; Calcium Channel Blockers; Fructose; Hyperinsulinism; Hypertension; Insulin Resistance; Male; Mibefradil; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Triglycerides	1997
Mibefradil--a new calcium-channel blocker. The Medical letter on drugs and therapeutics, 1997, Nov-07, Volume: 39, Issue:1013 Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Clinical Trials as Topic; Contraindications; Drug Administration Schedule; Drug Interactions; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1997
[Mibefradil: a new class calcium inhibitor]. Der Internist, 1996, Volume: 37, Issue:10 Suppl M Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1996
[Introducing mibefradil--a new T-calcium channel blocker]. Der Internist, 1997, Volume: 38, Issue:12 Suppl M Topics: Antihypertensive Agents; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes	1997
Different effects of calcium antagonists on fluid filtration of large arteries and albumin permeability in spontaneously hypertensive rats. Journal of hypertension, 1998, Volume: 16, Issue:3 Topics: Amlodipine; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Capillary Permeability; Carotid Arteries; Edema; Heart Rate; Hemodynamics; Hypertension; Male; Mibefradil; Nifedipine; Rats; Rats, Inbred SHR; Serum Albumin; Tetrahydronaphthalenes	1998
[Induction of bradycardia by mibefradil in antihypertensive combination therapy]. Deutsche medizinische Wochenschrift (1946), 1998, Apr-24, Volume: 123, Issue:17 Topics: Adult; Antihypertensive Agents; Benzimidazoles; Bradycardia; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Hypertension; Male; Mibefradil; Tetrahydronaphthalenes	1998
Mibefradil: a new twist to the calcium channel antagonist. The Nurse practitioner, 1998, Volume: 23, Issue:5 Topics: Benzimidazoles; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Mibefradil; Tetrahydronaphthalenes	1998
Pharmacokinetic interaction between oral cyclosporin and mibefradil in stabilized post-renal-transplant patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:7 Topics: Administration, Oral; Adult; Aged; Benzimidazoles; Calcium Channel Blockers; Cyclosporine; Drug Interactions; Female; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Mibefradil; Middle Aged; Tetrahydronaphthalenes	1998
Withdrawal of Posicor from market. Circulation, 1998, Sep-01, Volume: 98, Issue:9 Topics: Benzimidazoles; Calcium Channel Blockers; Drug Approval; Humans; Hypertension; Mibefradil; Product Surveillance, Postmarketing; Tetrahydronaphthalenes	1998
Clearing up confusion about hypertension drugs. Harvard health letter, 1998, Volume: 23, Issue:12 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzimidazoles; Benzothiadiazines; Calcium Channel Blockers; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Mibefradil; Sodium Chloride Symporter Inhibitors; Tetrahydronaphthalenes	1998
Serious interaction between mibefradil and tacrolimus. Transplantation, 1998, Oct-27, Volume: 66, Issue:8 Topics: Benzimidazoles; Calcium Channel Blockers; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Female; Humans; Hypertension; Immunosuppressive Agents; Liver Transplantation; Mibefradil; Middle Aged; Tacrolimus; Tetrahydronaphthalenes	1998
Differential effects of T- and L-type calcium antagonists on glomerular dynamics in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:2 Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Creatinine; Data Interpretation, Statistical; Enzyme Inhibitors; Glomerular Filtration Rate; Heart; Hemodynamics; Hypertension; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Mibefradil; Nephrocalcinosis; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Inbred SHR; Tetrahydronaphthalenes; Uric Acid; Vasodilator Agents	1999
Changes of cardiac calcium homeostasis in spontaneously hypertensive rats. Journal of autonomic pharmacology, 1999, Volume: 19, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Heart Ventricles; Homeostasis; Hypertension; In Vitro Techniques; Isoproterenol; Male; Mibefradil; Myocardial Contraction; Myocardium; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine	1999
Contrasting effects of selective T- and L-type calcium channel blockade on glomerular damage in DOCA hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:4 Pt 1 Topics: Amlodipine; Analysis of Variance; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels; Coronary Circulation; Desoxycorticosterone; Hemodynamics; Hypertension; Kidney Glomerulus; Male; Mibefradil; Organ Size; Rats; Rats, Wistar; Renin	1999
Mibefradil prevents L-NAME-exacerbated nephrosclerosis in spontaneously hypertensive rats. Journal of hypertension, 1999, Volume: 17, Issue:10 Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Antagonism; Enzyme Inhibitors; Hypertension; Mibefradil; Nephrosclerosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR	1999
Torsades de pointes caused by Mibefradil. European journal of heart failure, 2001, Volume: 3, Issue:5 Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Female; Humans; Hypertension; Long QT Syndrome; Mibefradil; Tachycardia, Ventricular; Torsades de Pointes	2001
Effect of nitric oxide synthase inhibitor N(omega) nitro-L-arginine methyl ester on relaxant responses to calcium channel antagonists in isolated aortic rings from Dahl normotensive and hypertensive rats. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:3 Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Female; Hypertension; Imidazoles; In Vitro Techniques; Mibefradil; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Vasoconstrictor Agents; Vasodilation	2002
A post-marketing observational study to assess the safety of mibefradil in the community in England. International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angina Pectoris; Calcium Channel Blockers; Dizziness; Drug and Narcotic Control; Drug Interactions; Edema; England; Fatigue; Female; Headache; Humans; Hypertension; Male; Mibefradil; Middle Aged; Product Surveillance, Postmarketing	2002
Antihypertensive properties of the novel calcium antagonist (1S,2S)-2-[2-[[3-(2-benzimidazolyl)propyl]methylamino] ethyl]-6- fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride in rat models of hypertension. Comparison with ver Arzneimittel-Forschung, 1990, Volume: 40, Issue:4 Topics: Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Heart Rate; Hypertension; Male; Mibefradil; Naphthalenes; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Tetrahydronaphthalenes; Verapamil	1990