Page last updated: 2024-10-31

mianserin and Weight Reduction

mianserin has been researched along with Weight Reduction in 7 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Research Excerpts

ExcerptRelevanceReference
"In a randomized, placebo-controlled trial, mirtazapine significantly improved early satiation, quality of life, gastrointestinal-specific anxiety, nutrient tolerance, and weight loss in patients with FD."9.22Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss. ( Arts, J; Boeckxstaens, G; Caenepeel, P; Carbone, F; Holvoet, L; Ly, HG; Tack, J; Van Oudenhove, L; Vanheel, H; Vanuytsel, T, 2016)
"Mirtazapine not only alleviates symptoms associated with dyspepsia and depression linked to FD in patients with weight loss but also significantly increases body weight (mainly the visceral fat in body fat)."9.22Beneficial effects of antidepressant mirtazapine in functional dyspepsia patients with weight loss. ( Jia, L; Jiang, SM; Liu, J; Shi, MM; Xu, MZ, 2016)
"Three patients with dementia and depression complicated by weight loss, insomnia, and anxiety were treated with mirtazapine at an outpatient memory loss clinic of a university hospital."7.71Mirtazapine for treatment of depression and comorbidities in Alzheimer disease. ( Brady, SR; Raji, MA, 2001)
"In a randomized, placebo-controlled trial, mirtazapine significantly improved early satiation, quality of life, gastrointestinal-specific anxiety, nutrient tolerance, and weight loss in patients with FD."5.22Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss. ( Arts, J; Boeckxstaens, G; Caenepeel, P; Carbone, F; Holvoet, L; Ly, HG; Tack, J; Van Oudenhove, L; Vanheel, H; Vanuytsel, T, 2016)
"Mirtazapine not only alleviates symptoms associated with dyspepsia and depression linked to FD in patients with weight loss but also significantly increases body weight (mainly the visceral fat in body fat)."5.22Beneficial effects of antidepressant mirtazapine in functional dyspepsia patients with weight loss. ( Jia, L; Jiang, SM; Liu, J; Shi, MM; Xu, MZ, 2016)
"Three patients with dementia and depression complicated by weight loss, insomnia, and anxiety were treated with mirtazapine at an outpatient memory loss clinic of a university hospital."3.71Mirtazapine for treatment of depression and comorbidities in Alzheimer disease. ( Brady, SR; Raji, MA, 2001)
"Changes in body weight can affect the overall health of an older patient and should not be considered a normal part of the aging process."1.40Potential role of mirtazapine in underweight older adults. ( Avena-Woods, C; Hilas, O, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hilas, O1
Avena-Woods, C1
Tanidir, C1
Tanidir, IC1
Tuzcu, V1
Tack, J1
Ly, HG1
Carbone, F1
Vanheel, H1
Vanuytsel, T1
Holvoet, L1
Boeckxstaens, G1
Caenepeel, P1
Arts, J1
Van Oudenhove, L1
Jiang, SM1
Jia, L1
Liu, J1
Shi, MM1
Xu, MZ1
Fox, CB1
Treadway, AK1
Blaszczyk, AT1
Sleeper, RB1
Goldberg, RJ1
Raji, MA1
Brady, SR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Mirtazapine Versus Placebo on Appetite, Nutritional Status and Quality of Life in Non-small Cell Lung cáncer Patients With Anorexia; Randomized Double-blind Clinical Trial.[NCT04748523]86 participants (Actual)Interventional2018-08-29Completed
Phase 4 Study of Mirtazapine in Functional Dyspepsia Patients With Weight Loss[NCT01240096]Phase 435 participants (Anticipated)Interventional2006-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for mianserin and Weight Reduction

ArticleYear
Megestrol acetate and mirtazapine for the treatment of unplanned weight loss in the elderly.
    Pharmacotherapy, 2009, Volume: 29, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Appetite Stimulants; Cachexia; Case-Control Studies; Dose-Re

2009

Trials

2 trials available for mianserin and Weight Reduction

ArticleYear
Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2016, Volume: 14, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Anxiety; Double-Blind Method; Dyspepsia; Female; Humans;

2016
Beneficial effects of antidepressant mirtazapine in functional dyspepsia patients with weight loss.
    World journal of gastroenterology, 2016, Jun-14, Volume: 22, Issue:22

    Topics: Adiposity; Adult; Affect; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic

2016

Other Studies

4 other studies available for mianserin and Weight Reduction

ArticleYear
Potential role of mirtazapine in underweight older adults.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2014, Volume: 29, Issue:2

    Topics: Aged; Antidepressive Agents, Tricyclic; Appetite; Body Weight; Humans; Mianserin; Mirtazapine; Quali

2014
Treatment of depression in an adolescent with cardiomyopathy and arrhythmia.
    Cardiology in the young, 2015, Volume: 25, Issue:7

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Anxiety; Cardiomyopathy, Hypertrophic; Depression; Ele

2015
Weight change in depressed nursing home patients on mirtazapine.
    Journal of the American Geriatrics Society, 2002, Volume: 50, Issue:8

    Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Female; Homes for the Aged; Humans; Male; Mianse

2002
Mirtazapine for treatment of depression and comorbidities in Alzheimer disease.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents, Tricyclic; Comorbidity; Depressio

2001