mianserin has been researched along with Torsade de Pointes in 2 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Citalopram is a selective serotonin reuptake inhibitor with a favorable cardiac-safety profile." | 1.38 | Prolonged QTc interval and torsades de pointes induced by citalopram. ( Abuissa, H; Airey, K; Alla, V; Deshmukh, A; Ulveling, K, 2012) |
| "Citalopram overdose was more likely to be associated with QT higher than the nomogram compared with the other agents (difference 7." | 1.36 | Evaluation of a QT nomogram for risk assessment after antidepressant overdose. ( Bateman, DN; Graham, A; Gray, J; Howell, C; Waring, WS; Wilson, AD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Waring, WS | 1 |
| Graham, A | 1 |
| Gray, J | 1 |
| Wilson, AD | 1 |
| Howell, C | 1 |
| Bateman, DN | 1 |
| Deshmukh, A | 1 |
| Ulveling, K | 1 |
| Alla, V | 1 |
| Abuissa, H | 1 |
| Airey, K | 1 |
2 other studies available for mianserin and Torsade de Pointes
| Article | Year |
|---|---|
Evaluation of a QT nomogram for risk assessment after antidepressant overdose.
Topics: Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Drug Overdose; Electrocardiography; Female; | 2010 |
Prolonged QTc interval and torsades de pointes induced by citalopram.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Depre | 2012 |