Page last updated: 2024-10-31

mianserin and Rett Syndrome

mianserin has been researched along with Rett Syndrome in 1 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)

Research Excerpts

ExcerptRelevanceReference
"Mirtazapine was more effective than desipramine in restoring somatosensory cortex thickness by fully rescuing pyramidal neurons dendritic arborization and spine density."5.43Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice. ( Baj, G; Bernareggi, A; Bittolo, T; Deiana, C; Ferrazzo, S; Raminelli, CA; Tongiorgi, E; Vaghi, V, 2016)
"Mirtazapine was more effective than desipramine in restoring somatosensory cortex thickness by fully rescuing pyramidal neurons dendritic arborization and spine density."1.43Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice. ( Baj, G; Bernareggi, A; Bittolo, T; Deiana, C; Ferrazzo, S; Raminelli, CA; Tongiorgi, E; Vaghi, V, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bittolo, T1
Raminelli, CA1
Deiana, C1
Baj, G1
Vaghi, V1
Ferrazzo, S1
Bernareggi, A1
Tongiorgi, E1

Other Studies

1 other study available for mianserin and Rett Syndrome

ArticleYear
Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice.
    Scientific reports, 2016, Jan-25, Volume: 6

    Topics: Animals; Antidepressive Agents; Atrophy; Breath Tests; Cerebral Cortex; Desipramine; GABAergic Neuro

2016