Page last updated: 2024-10-31

mianserin and Restless Legs Syndrome

mianserin has been researched along with Restless Legs Syndrome in 11 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Restless Legs Syndrome: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.

Research Excerpts

ExcerptRelevanceReference
"Mirtazapine is known to often provoke restless legs syndrome (RLS)."7.74Factors potentiating the risk of mirtazapine-associated restless legs syndrome. ( Kim, JM; Kim, SW; Park, KH; Shin, IS; Yoon, JS; Youn, T, 2008)
"Restless legs syndrome was observed in three patients receiving mianserin."7.67Mianserin-induced restless legs syndrome. ( Chae, YL; Choi, BM; Kim, CE; Lee, C; Paik, IH, 1989)
"Mirtazapine is known to often provoke restless legs syndrome (RLS)."3.74Factors potentiating the risk of mirtazapine-associated restless legs syndrome. ( Kim, JM; Kim, SW; Park, KH; Shin, IS; Yoon, JS; Youn, T, 2008)
"Six cases of restless legs syndrome in association to mianserin are presented."3.69Mianserin and restless legs. ( Lauerma, H; Markkula, J, 1997)
"Restless legs syndrome was observed in three patients receiving mianserin."3.67Mianserin-induced restless legs syndrome. ( Chae, YL; Choi, BM; Kim, CE; Lee, C; Paik, IH, 1989)
" In 9% of patients, RLS was recorded as a side effect related to the administration of AD."1.35Restless legs syndrome as side effect of second generation antidepressants. ( Gallwitz, T; Kirch, MH; Messer, T; Rottach, KG; Schaner, BM; Teufel, LM; Zivotofsky, AZ, 2008)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's1 (9.09)18.2507
2000's8 (72.73)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Makiguchi, A1
Nishida, M1
Shioda, K1
Suda, S1
Nisijima, K1
Kato, S1
Kim, SW1
Shin, IS1
Kim, JM1
Park, KH1
Youn, T1
Yoon, JS1
Ağargün, MY1
Kara, H1
Ozbek, H1
Tombul, T1
Ozer, OA1
Teive, HA1
de Quadros, A1
Barros, FC1
Werneck, LC1
Pae, CU2
Kim, TS1
Kim, JJ1
Chae, JH2
Lee, CU1
Lee, SJ1
Paik, IH2
Lee, C2
Chang, CC1
Shiah, IS1
Chang, HA1
Mao, WC1
Prospero-Garcia, KA1
Torres-Ruiz, A1
Ramirez-Bermudez, J1
Velazquez-Moctezuma, J1
Arana-Lechuga, Y1
Teran-Perez, G1
Rottach, KG1
Schaner, BM1
Kirch, MH1
Zivotofsky, AZ1
Teufel, LM1
Gallwitz, T1
Messer, T1
Markkula, J1
Lauerma, H1
Bahk, WM1
Jun, TY1
Kim, KS1
Choi, BM1
Chae, YL1
Kim, CE1

Trials

1 trial available for mianserin and Restless Legs Syndrome

ArticleYear
Fluoxetine-mirtazapine interaction may induce restless legs syndrome: report of 3 cases from a clinical trial.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:11

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Drug Interactions; Drug Therapy, Combinati

2006

Other Studies

10 other studies available for mianserin and Restless Legs Syndrome

ArticleYear
Mirtazapine-induced restless legs syndrome treated with pramipexole.
    The Journal of neuropsychiatry and clinical neurosciences, 2015,Winter, Volume: 27, Issue:1

    Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Female; H

2015
Factors potentiating the risk of mirtazapine-associated restless legs syndrome.
    Human psychopharmacology, 2008, Volume: 23, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Antidepressive Agents, Tricycl

2008
Restless legs syndrome induced by mirtazapine.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder, Major; Humans; Male; Mianserin; Middle Aged; Mirtazapine

2002
[Worsening of autosomal dominant restless legs syndrome after use of mirtazapine: case report].
    Arquivos de neuro-psiquiatria, 2002, Volume: 60, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Female; Genes, Dominant; Humans; Mianserin; Mirt

2002
Re-administration of mirtazapine could overcome previous mirtazapine- associated restless legs syndrome?
    Psychiatry and clinical neurosciences, 2004, Volume: 58, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Female; Humans; Mianserin; Middle Aged

2004
Does domperidone potentiate mirtazapine-associated restless legs syndrome?
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Domperidone; Dopamine Antagonis

2006
Restless legs syndrome as side effect of second generation antidepressants.
    Journal of psychiatric research, 2008, Volume: 43, Issue:1

    Topics: Acute Disease; Adult; Antidepressive Agents; Citalopram; Depressive Disorder; Depressive Disorder, M

2008
Mianserin and restless legs.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Arm; Female; Humans; Leg; Male; Mianserin; Mi

1997
Mirtazapine may have the propensity for developing a restless legs syndrome? A case report.
    Psychiatry and clinical neurosciences, 2002, Volume: 56, Issue:2

    Topics: Depressive Disorder; Electroencephalography; Female; Histamine H1 Antagonists; Humans; Mianserin; Mi

2002
Mianserin-induced restless legs syndrome.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 155

    Topics: Adult; Depressive Disorder; Female; Humans; Mianserin; Middle Aged; Restless Legs Syndrome

1989