mianserin has been researched along with Parkinsonian Disorders in 7 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Shortly after initiation of mirtazapine (a noradrenergic and serotonergic antidepressant) treatment in four patients with parkinsonism, the authors observed the appearance of REM sleep behavior disorder (RBD)." | 7.72 | Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. ( D'Andreamatteo, G; Iacono, D; Luciano, AL; Onofrj, M; Thomas, A, 2003) |
| "Shortly after initiation of mirtazapine (a noradrenergic and serotonergic antidepressant) treatment in four patients with parkinsonism, the authors observed the appearance of REM sleep behavior disorder (RBD)." | 3.72 | Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. ( D'Andreamatteo, G; Iacono, D; Luciano, AL; Onofrj, M; Thomas, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Godschalx-Dekker, JA | 1 |
| Siegers, HP | 1 |
| Holtz, NA | 1 |
| Tedford, SE | 1 |
| Persons, AL | 1 |
| Grasso, SA | 1 |
| Napier, TC | 1 |
| Hamadjida, A | 1 |
| Nuara, SG | 1 |
| Veyres, N | 1 |
| Frouni, I | 1 |
| Kwan, C | 1 |
| Sid-Otmane, L | 1 |
| Harraka, MJ | 1 |
| Gourdon, JC | 1 |
| Huot, P | 1 |
| Neumane, S | 1 |
| Mounayar, S | 1 |
| Jan, C | 1 |
| Epinat, J | 1 |
| Ballanger, B | 1 |
| Costes, N | 1 |
| Féger, J | 1 |
| Thobois, S | 1 |
| François, C | 1 |
| Sgambato-Faure, V | 1 |
| Tremblay, L | 1 |
| Carlson, BB | 1 |
| Wisniecki, A | 1 |
| Salamone, JD | 1 |
| Onofrj, M | 1 |
| Luciano, AL | 1 |
| Thomas, A | 1 |
| Iacono, D | 1 |
| D'Andreamatteo, G | 1 |
| Nash, JR | 1 |
| Wilson, SJ | 1 |
| Potokar, JP | 1 |
| Nutt, DJ | 1 |
7 other studies available for mianserin and Parkinsonian Disorders
| Article | Year |
|---|---|
Reduction of parkinsonism and psychosis with mirtazapine: a case report.
Topics: Aged; Histamine H1 Antagonists; Humans; Male; Mianserin; Mirtazapine; Parkinsonian Disorders; Psycho | 2014 |
Pharmacologically distinct pramipexole-mediated akinesia vs. risk-taking in a rat model of Parkinson's disease.
Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Corpus Striatum; De | 2016 |
The effect of mirtazapine on dopaminergic psychosis and dyskinesia in the parkinsonian marmoset.
Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Behavior, Animal; Callithrix; Dyski | 2017 |
Effects of dopamine and serotonin antagonist injections into the striatopallidal complex of asymptomatic MPTP-treated monkeys.
Topics: Animals; Chlorocebus aethiops; Corpus Striatum; Dopamine Antagonists; Flupenthixol; Macaca fascicula | 2012 |
Local injections of the 5-hydroxytryptamine antagonist mianserin into substantia nigra pars reticulata block tremulous jaw movements in rats: studies with a putative model of Parkinsonian tremor.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections; | 2003 |
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Electroencephalography; Humans; Levodopa; Male; | 2003 |
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Drug Administration Schedule; Hu | 2003 |