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mianserin and Parkinson Disease, Secondary

mianserin has been researched along with Parkinson Disease, Secondary in 2 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Research Excerpts

ExcerptRelevanceReference
"Rats treated with haloperidol at doses of 0."1.37Reversal of haloperidol-induced motor deficits by mianserin and mesulergine in rats. ( Haleem, DJ; Shireen, E, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shireen, E1
Haleem, DJ1
Korsgaard, S1
Friis, T1

Trials

1 trial available for mianserin and Parkinson Disease, Secondary

ArticleYear
Effects of mianserin in neuroleptic-induced parkinsonism.
    Psychopharmacology, 1986, Volume: 88, Issue:1

    Topics: Adult; Aged; Antipsychotic Agents; Dibenzazepines; Humans; Male; Mianserin; Middle Aged; Parasympath

1986

Other Studies

1 other study available for mianserin and Parkinson Disease, Secondary

ArticleYear
Reversal of haloperidol-induced motor deficits by mianserin and mesulergine in rats.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:1

    Topics: Animals; Antipsychotic Agents; Catalepsy; Dopamine Agonists; Dyskinesia, Drug-Induced; Ergolines; Ha

2011