Page last updated: 2024-10-31

mianserin and Panic Disorder

mianserin has been researched along with Panic Disorder in 11 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.

Research Excerpts

ExcerptRelevanceReference
"The aim of this open label trial was to evaluate mirtazapine tolerability and effectiveness in controlling symptomatology of patients with panic disorder."9.10Mirtazapine in the treatment of panic disorder: an open-label trial. ( Amore, M; Balista, C; Camardese, G; Carli, V; De Risio, S; Faia, V; Ferrari, G; Poterzio, F; Sarchiapone, M, 2003)
"Mirtazapine is an antidepressant whose side effect profile differs from that of first-line agents (selective serotonin reuptake inhibitors) used in the treatment of panic disorder."9.09Mirtazapine versus fluoxetine in the treatment of panic disorder. ( Busnello, EA; Busnello, JV; Kapczinski, F; Kauer-Sant'Anna, M; Madruga, M; Quevedo, J; Ribeiro, L, 2001)
"In this open label pilot study, we studied the efficacy of mirtazapine (Remeron) in panic disorder."9.09The effect of mirtazapine in panic disorder: an open label pilot study with a single-blind placebo run-in period. ( Boshuisen, ML; den Boer, JA; Slaap, BR; Vester-Blokland, ED, 2001)
" This report presents the beneficial effect of low-dose mirtazapine added onto selective serotonin reuptake inhibitors in the treatment of the symptoms of severe nausea, insomnia and loss of appetite accompanying psychiatric disorders during pregnancy, which is an important problem in clinical practice."7.79Low-dose mirtazapine added to selective serotonin reuptake inhibitors in pregnant women with major depression or panic disorder including symptoms of severe nausea, insomnia and decreased appetite: three cases. ( Uguz, F, 2013)
"The aim of this open label trial was to evaluate mirtazapine tolerability and effectiveness in controlling symptomatology of patients with panic disorder."5.10Mirtazapine in the treatment of panic disorder: an open-label trial. ( Amore, M; Balista, C; Camardese, G; Carli, V; De Risio, S; Faia, V; Ferrari, G; Poterzio, F; Sarchiapone, M, 2003)
"Mirtazapine is an antidepressant whose side effect profile differs from that of first-line agents (selective serotonin reuptake inhibitors) used in the treatment of panic disorder."5.09Mirtazapine versus fluoxetine in the treatment of panic disorder. ( Busnello, EA; Busnello, JV; Kapczinski, F; Kauer-Sant'Anna, M; Madruga, M; Quevedo, J; Ribeiro, L, 2001)
"In this open label pilot study, we studied the efficacy of mirtazapine (Remeron) in panic disorder."5.09The effect of mirtazapine in panic disorder: an open label pilot study with a single-blind placebo run-in period. ( Boshuisen, ML; den Boer, JA; Slaap, BR; Vester-Blokland, ED, 2001)
"Current studies do not yet provide convincing evidence supporting the efficacy of mirtazapine, reboxetine, milnacipran and duloxetine for the treatment of panic disorder patients."4.87Novel antidepressants and panic disorder: evidence beyond current guidelines. ( Bellodi, L; Calati, R; Chiesa, A; De Ronchi, D; Perna, G; Serretti, A, 2011)
" This report presents the beneficial effect of low-dose mirtazapine added onto selective serotonin reuptake inhibitors in the treatment of the symptoms of severe nausea, insomnia and loss of appetite accompanying psychiatric disorders during pregnancy, which is an important problem in clinical practice."3.79Low-dose mirtazapine added to selective serotonin reuptake inhibitors in pregnant women with major depression or panic disorder including symptoms of severe nausea, insomnia and decreased appetite: three cases. ( Uguz, F, 2013)
"Mirtazapine is an antidepressant with mode of action different from other currently available antidepressants."2.40Mirtazapine: other indications. ( Falkai, P, 1999)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Serretti, A1
Chiesa, A1
Calati, R1
Perna, G1
Bellodi, L1
De Ronchi, D1
Udo, I1
Gash, A1
Uguz, F1
Sarchiapone, M2
Amore, M1
De Risio, S1
Carli, V2
Faia, V1
Poterzio, F1
Balista, C1
Camardese, G2
Ferrari, G1
Carpenter, LL1
Leon, Z1
Yasmin, S1
Price, LH1
Falkai, P1
Klesmer, J1
Sarcevic, A1
Fomari, V1
Ribeiro, L1
Busnello, JV1
Kauer-Sant'Anna, M1
Madruga, M1
Quevedo, J1
Busnello, EA1
Kapczinski, F1
Boshuisen, ML2
Slaap, BR2
Vester-Blokland, ED1
den Boer, JA2
van Roon, AM1
Romano, L1
DeRisio, S1

Reviews

2 reviews available for mianserin and Panic Disorder

ArticleYear
Novel antidepressants and panic disorder: evidence beyond current guidelines.
    Neuropsychobiology, 2011, Volume: 63, Issue:1

    Topics: Antidepressive Agents; Clinical Trials as Topic; Cyclopropanes; Duloxetine Hydrochloride; Humans; Mi

2011
Mirtazapine: other indications.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety Disorders; Clinical Trials as Topic; Depressive Dis

1999

Trials

6 trials available for mianserin and Panic Disorder

ArticleYear
Mirtazapine in the treatment of panic disorder: an open-label trial.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:1

    Topics: Adult; Comorbidity; Depressive Disorder; Female; Histamine H1 Antagonists; Humans; Male; Mianserin;

2003
Clinical experience with mirtazapine in the treatment of panic disorder.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1999, Volume: 11, Issue:2

    Topics: Adult; Ambulatory Care; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Drug Administration

1999
Mirtazapine versus fluoxetine in the treatment of panic disorder.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2001, Volume: 34, Issue:10

    Topics: Adolescent; Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Double-Blind Method; Fema

2001
The effect of mirtazapine in panic disorder: an open label pilot study with a single-blind placebo run-in period.
    International clinical psychopharmacology, 2001, Volume: 16, Issue:6

    Topics: Adult; Antidepressive Agents, Tricyclic; Female; Humans; Male; Mianserin; Mirtazapine; Panic Disorde

2001
Heart rate variability as predictor of nonresponse to mirtazapine in panic disorder: a preliminary study.
    International clinical psychopharmacology, 2002, Volume: 17, Issue:2

    Topics: Adult; Agoraphobia; Antidepressive Agents, Tricyclic; Electrocardiography; Female; Heart Rate; Human

2002
Mirtazapine in the treatment of panic disorder.
    Archives of general psychiatry, 2002, Volume: 59, Issue:7

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Female; Gyrus Cinguli; Hippocampus; Humans; Mal

2002

Other Studies

3 other studies available for mianserin and Panic Disorder

ArticleYear
Challenges in management of complex panic disorder in a palliative care setting.
    BMJ case reports, 2012, Oct-09, Volume: 2012

    Topics: Anti-Anxiety Agents; Anxiety; Breathing Exercises; Comorbidity; Death; Dibenzothiazepines; Eye Movem

2012
Low-dose mirtazapine added to selective serotonin reuptake inhibitors in pregnant women with major depression or panic disorder including symptoms of severe nausea, insomnia and decreased appetite: three cases.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:11

    Topics: Adult; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Feeding and E

2013
Panic attacks during discontinuation of mirtazepine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2000, Volume: 45, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Appendectomy; Dysthymic Disorder; Hernia, Umbilical; Humans; Male;

2000