mianserin has been researched along with Neutropenia in 15 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two cases of mianserin induced neutropenia associated with prolonged elimination of the drug were studied." | 7.67 | Possible mechanism for mianserin induced neutropenia associated with saturable elimination kinetics. ( Begg, EJ; Colls, BM; Moller, PW; O'Donnell, JL; Sharman, JR, 1985) |
| "Four episodes of neutropenia or agranulocytosis possibly caused by the tetracyclic antidepressant drug, mianserin hydrochloride, were reported to the Australian Adverse Drug Reactions Advisory Committee during the first year of the drug's general availability in Australia." | 7.66 | Mianserin: a possible cause of neutropenia and agranulocytosis. Adverse Drug Reactions Advisory Committee. ( , 1980) |
| "A 40-year old woman with a history of acute psychotic symptoms developed agranulocytosis and neutropenia after starting therapy that included lamotrigine, mirtazapine, quetiapine, and venlafaxine." | 3.78 | Fatal agranulocytosis associated with psychotropic medication use. ( Al-Najjar, T; Ali, BA; Nazer, LH; Shankar, G, 2012) |
| "Two cases of mianserin induced neutropenia associated with prolonged elimination of the drug were studied." | 3.67 | Possible mechanism for mianserin induced neutropenia associated with saturable elimination kinetics. ( Begg, EJ; Colls, BM; Moller, PW; O'Donnell, JL; Sharman, JR, 1985) |
| "Four episodes of neutropenia or agranulocytosis possibly caused by the tetracyclic antidepressant drug, mianserin hydrochloride, were reported to the Australian Adverse Drug Reactions Advisory Committee during the first year of the drug's general availability in Australia." | 3.66 | Mianserin: a possible cause of neutropenia and agranulocytosis. Adverse Drug Reactions Advisory Committee. ( , 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, AY | 1 |
| Golewale, MH | 1 |
| Kahn, DA | 1 |
| Nazer, LH | 1 |
| Shankar, G | 1 |
| Ali, BA | 1 |
| Al-Najjar, T | 1 |
| Estabrook, KR | 1 |
| Pheister, M | 1 |
| Ahmed, A | 1 |
| Anghelescu, I | 1 |
| Klawe, C | 1 |
| Dahmen, N | 1 |
| Ozcanli, T | 1 |
| Unsalver, B | 1 |
| Ozdemir, S | 1 |
| Ozmen, M | 1 |
| Braye, SG | 1 |
| Copplestone, JA | 1 |
| Gartell, PC | 1 |
| Adams, PC | 1 |
| Robinson, A | 1 |
| Reid, MM | 1 |
| Vishu, MC | 1 |
| Livingston, M | 1 |
| Wilcox, JB | 1 |
| Edwards, IR | 1 |
| O'Donnell, JL | 1 |
| Sharman, JR | 1 |
| Begg, EJ | 1 |
| Colls, BM | 1 |
| Moller, PW | 1 |
| Forgan-Smith, J | 1 |
| Leslie, P | 1 |
15 other studies available for mianserin and Neutropenia
| Article | Year |
|---|---|
A case of chronic drug-induced neutropenia.
Topics: Anti-Anxiety Agents; Anti-Infective Agents; Anxiety Disorders; Chronic Disease; Female; Humans; Metr | 2008 |
Fatal agranulocytosis associated with psychotropic medication use.
Topics: Adult; Agranulocytosis; Antidepressive Agents, Second-Generation; Antimanic Agents; Antipsychotic Ag | 2012 |
A case of quetiapine XR and divalproex-associated neutropenia followed by successful use of ziprasidone.
Topics: Adult; Anti-Anxiety Agents; Antimanic Agents; Antipsychotic Agents; Anxiety Disorders; Bipolar Disor | 2012 |
Neutropenia associated with mirtazapine use: is a drop in the neutrophil count in a symptomatic older adults a cause for concern?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents, Tricyclic; Depression; Female; Hu | 2002 |
Venlafaxine in a patient with idiopathic leukopenia and mirtazapine-induced severe neutropenia.
Topics: Agranulocytosis; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Comorbi | 2002 |
Mirtazapine: seizures and neutropenia.
Topics: Antidepressive Agents; Australia; Humans; Mianserin; Neutropenia; Seizures | 2004 |
Sertraline- and mirtazapine-induced severe neutropenia.
Topics: Adult; Agranulocytosis; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Female; Humans | 2005 |
Adverse Drug Reactions Advisory Committee: ADRAC report for 1980.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Australia; Bronchial Spasm; Chemical and Drug Induced Live | 1982 |
Neutropenic enterocolitis during mianserin-induced agranulocytosis.
Topics: Aged; Agranulocytosis; Dibenzazepines; Enterocolitis, Pseudomembranous; Female; Humans; Mianserin; N | 1982 |
Blood dyscrasias and mianserin.
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Dibenzazepines; Female; Humans; Mianserin; Middle Ag | 1983 |
Neutropenia following mianserin.
Topics: Adult; Agranulocytosis; Dibenzazepines; Female; Humans; Mianserin; Neutropenia | 1982 |
Mianserin: a possible cause of neutropenia and agranulocytosis. Adverse Drug Reactions Advisory Committee.
Topics: Adult; Aged; Agranulocytosis; Depressive Disorder; Dibenzazepines; Female; Humans; Male; Mianserin; | 1980 |
Agranulocytosis and mianserin.
Topics: Adult; Aged; Agranulocytosis; Dibenzazepines; Female; Humans; Male; Mianserin; Middle Aged; Neutrope | 1985 |
Possible mechanism for mianserin induced neutropenia associated with saturable elimination kinetics.
Topics: Aged; Agranulocytosis; Bone Marrow; Dibenzazepines; Female; Humans; Kinetics; Leukocyte Count; Metab | 1985 |
Neutropenia and mianserin.
Topics: Aged; Agranulocytosis; Dibenzazepines; Humans; Male; Mianserin; Neutropenia | 1985 |