mianserin has been researched along with Nerve Pain in 8 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was designed to explore the effects and most appropriate dosage of mirtazapine in treating neuropathic pain and its possible neuroimmune mechanisms." | 5.35 | Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain. ( Feng, X; Hu, Y; Song, J; Wei, X; Xu, J; Zhu, J, 2008) |
| "Mirtazapine (MTZ) is a new and well-tolerated tricyclic antidepressants with both monoaminergic and opioid properties that might favorably influence pain." | 2.73 | Mirtazapine decreases the pain feeling in healthy participants. ( Arnold, P; Deriaz, O; Gobelet, C; Kuntzer, T; Vuadens, P, 2008) |
| "The effect of mianserin on hyperalgesia occurring in connection with peripheral diabetic neuropathy was examined using the Randall-Selitto (mechanical nociceptive stimulus), Hargreaves (thermal nociceptive stimulus), and cold-plate (4°C, thermal nociceptive stimulus) tests." | 1.42 | Antihyperalgesic and antiallodynic effects of mianserin on diabetic neuropathic pain: a study on mechanism of action. ( Can, ÖD; Demir Özkay, Ü; Öztürk, Y; Üçel, Uİ, 2015) |
| " Time-course data for the dose-response effects were analyzed using two-way analysis of variance and the posthoc Tukey-Kramer multiple-comparison test." | 1.40 | Antinociceptive effects of mirtazapine, pregabalin, and gabapentin after chronic constriction injury of the infraorbital nerve in rats. ( Hashimoto, R; Hosokawa, K; Mashimo, T; Nakae, A; Nakai, K, 2014) |
| "Mirtazapine (MTZ) is an antidepressant, which is considered to enhance noradrenergic and serotonergic neurotransmission via antagonistic action at central α2-adrenergic autoreceptors and heteroreceptors." | 1.38 | Effects of mirtazapine on sleep disturbance under neuropathic pain-like state. ( Enomoto, T; Hirayama, S; Horiuchi, H; Ikegami, D; Inada, E; Iseki, M; Nagase, H; Nakahara, K; Narita, M; Sakai, H; Suzuki, T; Torigoe, K; Yamashita, A; Yanase, M, 2012) |
| " All substances were dosed between 0." | 1.35 | Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats. ( Driehsen, C; Freynhagen, R; Hermanns, H; Lipfert, P; Muth-Selbach, U, 2009) |
| " The present study was designed to explore the effects and most appropriate dosage of mirtazapine in treating neuropathic pain and its possible neuroimmune mechanisms." | 1.35 | Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain. ( Feng, X; Hu, Y; Song, J; Wei, X; Xu, J; Zhu, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakai, K | 1 |
| Nakae, A | 1 |
| Hashimoto, R | 1 |
| Mashimo, T | 1 |
| Hosokawa, K | 1 |
| Iwanowski, P | 1 |
| Kozubski, W | 1 |
| Losy, J | 1 |
| Üçel, Uİ | 1 |
| Can, ÖD | 1 |
| Demir Özkay, Ü | 1 |
| Öztürk, Y | 1 |
| Muth-Selbach, U | 1 |
| Hermanns, H | 1 |
| Driehsen, C | 1 |
| Lipfert, P | 1 |
| Freynhagen, R | 1 |
| Enomoto, T | 1 |
| Yamashita, A | 1 |
| Torigoe, K | 1 |
| Horiuchi, H | 1 |
| Hirayama, S | 1 |
| Nakahara, K | 1 |
| Yanase, M | 1 |
| Sakai, H | 1 |
| Ikegami, D | 1 |
| Nagase, H | 1 |
| Suzuki, T | 1 |
| Iseki, M | 1 |
| Inada, E | 1 |
| Narita, M | 1 |
| Masuzawa, M | 1 |
| Taguchi, H | 1 |
| Sugimoto, T | 1 |
| Kojima, H | 1 |
| Matsumoto, S | 1 |
| Kojima, K | 1 |
| Shingu, K | 1 |
| Arnold, P | 1 |
| Vuadens, P | 1 |
| Kuntzer, T | 1 |
| Gobelet, C | 1 |
| Deriaz, O | 1 |
| Zhu, J | 1 |
| Wei, X | 1 |
| Feng, X | 1 |
| Song, J | 1 |
| Hu, Y | 1 |
| Xu, J | 1 |
1 trial available for mianserin and Nerve Pain
| Article | Year |
|---|---|
Mirtazapine decreases the pain feeling in healthy participants.
Topics: Adult; Analgesics; Antidepressive Agents, Tricyclic; Cross-Over Studies; Double-Blind Method; Drug A | 2008 |
7 other studies available for mianserin and Nerve Pain
| Article | Year |
|---|---|
Antinociceptive effects of mirtazapine, pregabalin, and gabapentin after chronic constriction injury of the infraorbital nerve in rats.
Topics: Adrenergic alpha-Antagonists; Amines; Analgesics; Animals; Cranial Nerve Injuries; Cyclohexanecarbox | 2014 |
Nummular headache in a patient with ipsilateral occipital neuralgia--a case report.
Topics: Amines; Analgesics; Anesthetics, Local; Bupivacaine; Comorbidity; Cyclohexanecarboxylic Acids; Femal | 2014 |
Antihyperalgesic and antiallodynic effects of mianserin on diabetic neuropathic pain: a study on mechanism of action.
Topics: Analgesics; Animals; Catecholamines; Diabetic Neuropathies; Hyperalgesia; Male; Mianserin; Neuralgia | 2015 |
Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats.
Topics: Analgesics; Animals; Antidepressive Agents; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; | 2009 |
Effects of mirtazapine on sleep disturbance under neuropathic pain-like state.
Topics: Animals; Disease Models, Animal; Histamine H1 Antagonists; Hyperalgesia; Male; Mianserin; Mice; Mice | 2012 |
[Case of successful management with mirtazapine for prolonged pain after esophagectomy].
Topics: Adrenergic alpha-Antagonists; Antidepressive Agents, Tricyclic; Esophageal Neoplasms; Esophagectomy; | 2012 |
Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cytokines; Denervation; Disease Models, Animal; Do | 2008 |