mianserin has been researched along with MPTP Neurotoxicity Syndrome in 3 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mirtazapine was also reported to increase dopamine release in the cortical neurons with 5-HT dependent manner." | 1.40 | Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease. ( Fukano, T; Kadoguchi, N; Kasahara, J; Okabe, S; Shono, M; Tanabe, A; Yamamura, Y; Yokoyama, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamadjida, A | 2 |
| Nuara, SG | 2 |
| Gourdon, JC | 2 |
| Huot, P | 2 |
| Kadoguchi, N | 1 |
| Okabe, S | 1 |
| Yamamura, Y | 1 |
| Shono, M | 1 |
| Fukano, T | 1 |
| Tanabe, A | 1 |
| Yokoyama, H | 1 |
| Kasahara, J | 1 |
| Veyres, N | 1 |
| Frouni, I | 1 |
| Kwan, C | 1 |
| Sid-Otmane, L | 1 |
| Harraka, MJ | 1 |
3 other studies available for mianserin and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
The effect of mianserin on the severity of psychosis and dyskinesia in the parkinsonian marmoset.
Topics: Animals; Antidepressive Agents, Second-Generation; Callithrix; Disease Models, Animal; Dose-Response | 2018 |
Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Disease Models, Animal; Feasibility Studies; Male; | 2014 |
The effect of mirtazapine on dopaminergic psychosis and dyskinesia in the parkinsonian marmoset.
Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Behavior, Animal; Callithrix; Dyski | 2017 |