mianserin has been researched along with Hyperemesis Gravidarum in 6 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Hyperemesis Gravidarum: Intractable VOMITING that develops in early PREGNANCY and persists. This can lead to DEHYDRATION and WEIGHT LOSS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we present the case of a 30-year-old woman with type I diabetes mellitus, preeclampsia and treatment resistant persistent hyperemesis gravidarum in her 25th week of gestation who was successfully treated with the antidepressant mirtazapine (Remergil)." | 7.74 | Treatment resistant hyperemesis gravidarum in a patient with type 1 diabetes mellitus: neonatal withdrawal symptoms after successful antiemetic therapy with mirtazapine. ( Gembruch, U; Heep, A; Rohde, A; Schwarzer, V, 2008) |
| "Mirtazapine seems to be an effective treatment modality in patients with severe hyperemesis gravidarum who do not respond to conventional anti-emesis treatment regimens." | 7.73 | Mirtazapine use in resistant hyperemesis gravidarum: report of three cases and review of the literature. ( Dogan, E; Gol, M; Guclu, S; Saygili, U, 2005) |
| " When the patient asked for termination of the pregnancy because of the unbearable symptoms, treatment with intravenous mirtazapine (Remergil) was started." | 7.72 | Mirtazapine (Remergil) for treatment resistant hyperemesis gravidarum: rescue of a twin pregnancy. ( Dembinski, J; Dorn, C; Rohde, A, 2003) |
| "Here we present the case of a 30-year-old woman with type I diabetes mellitus, preeclampsia and treatment resistant persistent hyperemesis gravidarum in her 25th week of gestation who was successfully treated with the antidepressant mirtazapine (Remergil)." | 3.74 | Treatment resistant hyperemesis gravidarum in a patient with type 1 diabetes mellitus: neonatal withdrawal symptoms after successful antiemetic therapy with mirtazapine. ( Gembruch, U; Heep, A; Rohde, A; Schwarzer, V, 2008) |
| "Mirtazapine seems to be an effective treatment modality in patients with severe hyperemesis gravidarum who do not respond to conventional anti-emesis treatment regimens." | 3.73 | Mirtazapine use in resistant hyperemesis gravidarum: report of three cases and review of the literature. ( Dogan, E; Gol, M; Guclu, S; Saygili, U, 2005) |
| " When the patient asked for termination of the pregnancy because of the unbearable symptoms, treatment with intravenous mirtazapine (Remergil) was started." | 3.72 | Mirtazapine (Remergil) for treatment resistant hyperemesis gravidarum: rescue of a twin pregnancy. ( Dembinski, J; Dorn, C; Rohde, A, 2003) |
| "Hyperemesis gravidarum is not uncommon." | 1.46 | Intractable hyperemesis gravidarum in a patient with type 1 diabetes. ( Arshad, MF; Bekhit, M; Javed, N, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arshad, MF | 1 |
| Javed, N | 1 |
| Bekhit, M | 1 |
| Abramowitz, A | 1 |
| Miller, ES | 1 |
| Wisner, KL | 1 |
| Lieb, M | 1 |
| Palm, U | 1 |
| Jacoby, D | 1 |
| Baghai, TC | 1 |
| Severus, E | 1 |
| Rohde, A | 2 |
| Dembinski, J | 1 |
| Dorn, C | 1 |
| Guclu, S | 1 |
| Gol, M | 1 |
| Dogan, E | 1 |
| Saygili, U | 1 |
| Schwarzer, V | 1 |
| Heep, A | 1 |
| Gembruch, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP)[NCT05452174] | Phase 1/Phase 2 | 25 participants (Anticipated) | Interventional | 2022-06-13 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mianserin and Hyperemesis Gravidarum
| Article | Year |
|---|---|
Treatment options for hyperemesis gravidarum.
Topics: Adrenergic alpha-Antagonists; Adult; Antiemetics; Dopamine Agonists; Female; Humans; Hyperemesis Gra | 2017 |
5 other studies available for mianserin and Hyperemesis Gravidarum
| Article | Year |
|---|---|
Intractable hyperemesis gravidarum in a patient with type 1 diabetes.
Topics: Antiemetics; Cesarean Section; Diabetes Mellitus, Type 1; Female; Gestational Age; Humans; Hyperemes | 2017 |
[Mirtazapine and hyperemesis gravidarum].
Topics: Adult; Antidepressive Agents, Tricyclic; Female; Humans; Hyperemesis Gravidarum; Mianserin; Mirtazap | 2012 |
Mirtazapine (Remergil) for treatment resistant hyperemesis gravidarum: rescue of a twin pregnancy.
Topics: Abortion, Induced; Adult; Antidepressive Agents, Tricyclic; Cesarean Section; Female; Humans; Hypere | 2003 |
Mirtazapine use in resistant hyperemesis gravidarum: report of three cases and review of the literature.
Topics: Adult; Antiemetics; Female; Humans; Hyperemesis Gravidarum; Infant, Newborn; Mianserin; Mirtazapine; | 2005 |
Treatment resistant hyperemesis gravidarum in a patient with type 1 diabetes mellitus: neonatal withdrawal symptoms after successful antiemetic therapy with mirtazapine.
Topics: Adult; Antidepressive Agents, Tricyclic; Diabetes Mellitus, Type 1; Drug Resistance; Female; Humans; | 2008 |