Page last updated: 2024-10-31

mianserin and Heart Failure

mianserin has been researched along with Heart Failure in 5 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
" Notably, noradrenergic and specific serotonergic antidepressant (mirtazapine) use was significantly associated with higher prevalence of heart failure (OR 3."3.79Association of antidepressant and atypical antipsychotic use with cardiovascular events and mortality in a veteran population. ( Acharya, S; Acharya, T; Huang, J; Tringali, S, 2013)
"Two patients, who were receiving therapy with mianserin for depressive disorders, developed signs of disturbed cardiac function which resolved after mianserin therapy was discontinued."3.67Disturbed cardiac function possibly associated with mianserin therapy. ( Evans, L; Klug, P; Whiteford, H, 1984)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Loyaga-Rendon, RY1
Taylor, DO1
Koval, CE1
Acharya, T1
Acharya, S1
Tringali, S1
Huang, J1
Whiteford, H1
Klug, P1
Evans, L1
Tulloch, AE1
Shaw, WL1

Other Studies

5 other studies available for mianserin and Heart Failure

ArticleYear
Progressive multifocal leukoencephalopathy in a heart transplant recipient following rituximab therapy for antibody-mediated rejection.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2013, Volume: 13, Issue:4

    Topics: Antibodies, Monoclonal, Murine-Derived; Cognition Disorders; Fatal Outcome; Graft Rejection; Heart F

2013
Association of antidepressant and atypical antipsychotic use with cardiovascular events and mortality in a veteran population.
    Pharmacotherapy, 2013, Volume: 33, Issue:10

    Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Cardiovascular Diseases; Cross-Sectional S

2013
Disturbed cardiac function possibly associated with mianserin therapy.
    The Medical journal of Australia, 1984, Feb-04, Volume: 140, Issue:3

    Topics: Aged; Atrial Fibrillation; Depressive Disorder; Dibenzazepines; Female; Heart Failure; Humans; Hypok

1984
Two clinical syndromes and mianserin.
    Lancet (London, England), 1978, May-20, Volume: 1, Issue:8073

    Topics: Adult; Antidepressive Agents, Tricyclic; Dibenzazepines; Dothiepin; Drug Synergism; Female; Heart Fa

1978
Mianserin.
    Lancet (London, England), 1978, Jul-01, Volume: 2, Issue:8079

    Topics: Dibenzazepines; Heart Failure; Humans; Mianserin; Unconsciousness

1978