mianserin has been researched along with Fibromyalgia in 5 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of mirtazapine in Japanese patients with fibromyalgia (FM), a parallel-group, randomized, double-blind, placebo-controlled phase IIa study was conducted at 57 sites between November 2012 and February 2014." | 9.22 | Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan. ( Miki, K; Murakami, M; Oka, H; Onozawa, K; Osada, K; Yoshida, S, 2016) |
| " Eighteen patients had at least moderate depression before mirtazapine treatment and 8 patients presented mild depressive symptoms." | 9.11 | Open trial of mirtazapine in patients with fibromyalgia. ( Lezanska-Szpera, M; Rybakowski, JK; Samborski, W, 2004) |
| "To assess the efficacy, tolerability and safety of the tetracyclic antidepressant, mirtazapine, compared with placebo or other active drug(s) in the treatment of fibromyalgia in adults." | 8.98 | Mirtazapine for fibromyalgia in adults. ( Bernardy, K; Derry, S; Häuser, W; Moore, RA; Welsch, P, 2018) |
| "To evaluate the efficacy and safety of mirtazapine in Japanese patients with fibromyalgia (FM), a parallel-group, randomized, double-blind, placebo-controlled phase IIa study was conducted at 57 sites between November 2012 and February 2014." | 5.22 | Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan. ( Miki, K; Murakami, M; Oka, H; Onozawa, K; Osada, K; Yoshida, S, 2016) |
| " Eighteen patients had at least moderate depression before mirtazapine treatment and 8 patients presented mild depressive symptoms." | 5.11 | Open trial of mirtazapine in patients with fibromyalgia. ( Lezanska-Szpera, M; Rybakowski, JK; Samborski, W, 2004) |
| "To assess the efficacy, tolerability and safety of the tetracyclic antidepressant, mirtazapine, compared with placebo or other active drug(s) in the treatment of fibromyalgia in adults." | 4.98 | Mirtazapine for fibromyalgia in adults. ( Bernardy, K; Derry, S; Häuser, W; Moore, RA; Welsch, P, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Welsch, P | 1 |
| Bernardy, K | 1 |
| Derry, S | 1 |
| Moore, RA | 1 |
| Häuser, W | 1 |
| Miki, K | 1 |
| Murakami, M | 1 |
| Oka, H | 1 |
| Onozawa, K | 1 |
| Yoshida, S | 1 |
| Osada, K | 1 |
| Samborski, W | 2 |
| Lezanska-Szpera, M | 2 |
| Rybakowski, JK | 2 |
| Tabeeva, GR | 1 |
| Levin, IaI | 1 |
| Korotkova, SB | 1 |
| Khanunov, IG | 1 |
1 review available for mianserin and Fibromyalgia
| Article | Year |
|---|---|
Mirtazapine for fibromyalgia in adults.
Topics: Adult; Antidepressive Agents, Tricyclic; Fibromyalgia; Humans; Mianserin; Mirtazapine; Randomized Co | 2018 |
3 trials available for mianserin and Fibromyalgia
| Article | Year |
|---|---|
Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan.
Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Depression; Double-Blind Method; Fema | 2016 |
Open trial of mirtazapine in patients with fibromyalgia.
Topics: Adrenergic alpha-Antagonists; Adult; Depression; Drug Administration Schedule; Female; Fibromyalgia; | 2004 |
Effects of antidepressant mirtazapine on fibromyalgia symptoms.
Topics: Adult; Antidepressive Agents, Tricyclic; Female; Fibromyalgia; Humans; Male; Mianserin; Middle Aged; | 2004 |
1 other study available for mianserin and Fibromyalgia
| Article | Year |
|---|---|
[Treatment of fibromyalgia].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Second-Generation; Anxiety Di | 1998 |