mianserin has been researched along with Electrocardiogram QT Prolonged in 4 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mirtazapine appears to be relatively benign in overdose, associated with tachycardia, mild hypertension and mild CNS depression not requiring intervention." | 3.80 | Mirtazapine overdose is unlikely to cause major toxicity. ( Berling, I; Isbister, GK, 2014) |
| "Mirtazapine is a commonly prescribed antidepressant drug, which is also metabolized through and may modulate the CYP4502D6 pathway leading to altered metabolism of propafenone and possible adverse effects." | 1.40 | Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction. ( Aryal, SR; Khan, MA; Rajpurohit, N; Stys, AT; Stys, TP, 2014) |
| "Citalopram overdose was more likely to be associated with QT higher than the nomogram compared with the other agents (difference 7." | 1.36 | Evaluation of a QT nomogram for risk assessment after antidepressant overdose. ( Bateman, DN; Graham, A; Gray, J; Howell, C; Waring, WS; Wilson, AD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berling, I | 1 |
| Isbister, GK | 1 |
| Rajpurohit, N | 1 |
| Aryal, SR | 1 |
| Khan, MA | 1 |
| Stys, AT | 1 |
| Stys, TP | 1 |
| Waring, WS | 1 |
| Graham, A | 1 |
| Gray, J | 1 |
| Wilson, AD | 1 |
| Howell, C | 1 |
| Bateman, DN | 1 |
| Hidalgo Urbano, RJ | 1 |
| Díaz Infante, E | 1 |
| Recio Mayoral, A | 1 |
| López Rincón, F | 1 |
| Gutiérrez de la Peña, J | 1 |
| Cruz Fernández, JM | 1 |
4 other studies available for mianserin and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Mirtazapine overdose is unlikely to cause major toxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Critical Care; Databases, Factual | 2014 |
Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction.
Topics: Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Atrial Fibrillation; Bradycardia; Di | 2014 |
Evaluation of a QT nomogram for risk assessment after antidepressant overdose.
Topics: Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Drug Overdose; Electrocardiography; Female; | 2010 |
[Enlargement of QT-interval in a patient with coronary disease treated with mianserin].
Topics: Aged; Antidepressive Agents, Second-Generation; Coronary Disease; Depression; Electrocardiography; F | 2003 |