mianserin has been researched along with Dyspepsia in 6 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Dyspepsia: Impaired digestion, especially after eating.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomized, placebo-controlled trial, mirtazapine significantly improved early satiation, quality of life, gastrointestinal-specific anxiety, nutrient tolerance, and weight loss in patients with FD." | 9.22 | Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss. ( Arts, J; Boeckxstaens, G; Caenepeel, P; Carbone, F; Holvoet, L; Ly, HG; Tack, J; Van Oudenhove, L; Vanheel, H; Vanuytsel, T, 2016) |
| "Mirtazapine not only alleviates symptoms associated with dyspepsia and depression linked to FD in patients with weight loss but also significantly increases body weight (mainly the visceral fat in body fat)." | 9.22 | Beneficial effects of antidepressant mirtazapine in functional dyspepsia patients with weight loss. ( Jia, L; Jiang, SM; Liu, J; Shi, MM; Xu, MZ, 2016) |
| "In a randomized, placebo-controlled trial, mirtazapine significantly improved early satiation, quality of life, gastrointestinal-specific anxiety, nutrient tolerance, and weight loss in patients with FD." | 5.22 | Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss. ( Arts, J; Boeckxstaens, G; Caenepeel, P; Carbone, F; Holvoet, L; Ly, HG; Tack, J; Van Oudenhove, L; Vanheel, H; Vanuytsel, T, 2016) |
| "Mirtazapine not only alleviates symptoms associated with dyspepsia and depression linked to FD in patients with weight loss but also significantly increases body weight (mainly the visceral fat in body fat)." | 5.22 | Beneficial effects of antidepressant mirtazapine in functional dyspepsia patients with weight loss. ( Jia, L; Jiang, SM; Liu, J; Shi, MM; Xu, MZ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tack, J | 1 |
| Ly, HG | 1 |
| Carbone, F | 1 |
| Vanheel, H | 1 |
| Vanuytsel, T | 1 |
| Holvoet, L | 1 |
| Boeckxstaens, G | 1 |
| Caenepeel, P | 1 |
| Arts, J | 1 |
| Van Oudenhove, L | 1 |
| Jiang, SM | 1 |
| Jia, L | 1 |
| Liu, J | 1 |
| Shi, MM | 1 |
| Xu, MZ | 1 |
| Zimmermann-Viehoff, F | 1 |
| Bergander, B | 1 |
| Meissner, K | 1 |
| Deter, HC | 1 |
| Lee, SY | 1 |
| Rho, SH | 1 |
| Choi, SC | 1 |
| Tanum, L | 2 |
| Malt, UF | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 4 Study of Mirtazapine in Functional Dyspepsia Patients With Weight Loss[NCT01240096] | Phase 4 | 35 participants (Anticipated) | Interventional | 2006-09-30 | Recruiting | ||
| Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia[NCT00547703] | 5 participants (Actual) | Interventional | 2008-02-29 | Terminated (stopped due to Not enough participants - only 5 since the study started) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient would answer yes or no to a simple question asking whether they had adequate relief of abdominal pain or discomfort. This was measured at weeks 2,4 and 8 of the study but only week 8 was reported. What is being reported is the number of participants who answered yes. (NCT00547703)
Timeframe: 8 weeks
| Intervention | participants (Number) |
|---|---|
| Nortriptyline | 2 |
| Placebo | 1 |
4 trials available for mianserin and Dyspepsia
| Article | Year |
|---|---|
Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Anxiety; Double-Blind Method; Dyspepsia; Female; Humans; | 2016 |
Beneficial effects of antidepressant mirtazapine in functional dyspepsia patients with weight loss.
Topics: Adiposity; Adult; Affect; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic | 2016 |
A new pharmacologic treatment of functional gastrointestinal disorder. A double-blind placebo-controlled study with mianserin.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Colonic Diseases, Functional; Dou | 1996 |
Personality traits predict treatment outcome with an antidepressant in patients with functional gastrointestinal disorder.
Topics: Adult; Aged; Aggression; Antidepressive Agents, Second-Generation; Colonic Diseases, Functional; Dys | 2000 |
2 other studies available for mianserin and Dyspepsia
| Article | Year |
|---|---|
[Integrative therapy of a patient with complex psychosomatic complaints].
Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Dyspepsia; Female; Humans; Integrative Medicine; | 2008 |
Functional dyspepsia and mirtazapine.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Dyspepsia; Female; Humans; Limbic Syst | 2002 |