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mianserin and Dyskinesia, Drug-Induced

mianserin has been researched along with Dyskinesia, Drug-Induced in 13 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
"The objective of the present study was to evaluate the efficacy of mianserin and trazodone as antidepressants with serotonin 2 antagonist properties on negative symptoms and tardive dyskinesia in elderly patients with chronic schizophrenia."9.08Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study. ( Fujikawa, T; Furutani, M; Hayashi, T; Horiguchi, J; Nishikawa, T; Takahashi, T; Tawara, Y; Yamawaki, S; Yano, T; Yokota, N, 1997)
"The objective of the present study was to evaluate the efficacy of mianserin and trazodone as antidepressants with serotonin 2 antagonist properties on negative symptoms and tardive dyskinesia in elderly patients with chronic schizophrenia."5.08Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study. ( Fujikawa, T; Furutani, M; Hayashi, T; Horiguchi, J; Nishikawa, T; Takahashi, T; Tawara, Y; Yamawaki, S; Yano, T; Yokota, N, 1997)
"Aripiprazole is a novel antipsychotic medication characterized by partial agonism at the D2 and 5-HT1A receptors and by antagonism at the 5-HT2A receptor."2.74Aripiprazole in L-dopa-induced dyskinesias: a one-year open-label pilot study. ( Bernardi, S; Edito, F; Meco, G; Purcaro, C; Stirpe, P; Valente, M; Vanacore, N, 2009)
" Adding risperidone to mirtazapine probably does not necessitate a change of the dosage of either drug, but more extensive investigations are needed."2.69Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study. ( Doorschot, CH; Loonen, AJ; Oostelbos, MC; Sitsen, JM, 1999)
"Rats treated with haloperidol at doses of 0."1.37Reversal of haloperidol-induced motor deficits by mianserin and mesulergine in rats. ( Haleem, DJ; Shireen, E, 2011)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's5 (38.46)18.2507
2000's3 (23.08)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamadjida, A2
Nuara, SG2
Gourdon, JC2
Huot, P2
Veyres, N1
Frouni, I1
Kwan, C1
Sid-Otmane, L1
Harraka, MJ1
Meco, G1
Stirpe, P1
Edito, F1
Purcaro, C1
Valente, M1
Bernardi, S1
Vanacore, N1
Shireen, E1
Haleem, DJ1
Konitsiotis, S1
Pappa, S1
Mantas, C1
Mavreas, V1
Kohen, I1
Sarcevic, A1
Sparring Björkstén, K1
Wålinder, J1
Hayashi, T1
Yokota, N1
Takahashi, T1
Tawara, Y1
Nishikawa, T1
Yano, T1
Furutani, M1
Fujikawa, T1
Horiguchi, J1
Yamawaki, S1
Stevens, E1
Roman, A1
Houa, M1
Razavi, D1
Jaspar, N1
Pact, V1
Giduz, T1
Loonen, AJ1
Doorschot, CH1
Oostelbos, MC1
Sitsen, JM1
Otani, K1
Kaneko, S1
Fukushima, Y1
Kubota, S1
Korsgaard, S1
Gerlach, J1
Christensson, E1

Trials

3 trials available for mianserin and Dyskinesia, Drug-Induced

ArticleYear
Aripiprazole in L-dopa-induced dyskinesias: a one-year open-label pilot study.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Amantadine; Antiparkinson Agents; Antipsychot

2009
Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:4

    Topics: Age Factors; Aged; Antidepressive Agents, Second-Generation; Brief Psychiatric Rating Scale; Double-

1997
Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 10, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depression; Depressive Disorder

1999

Other Studies

10 other studies available for mianserin and Dyskinesia, Drug-Induced

ArticleYear
The effect of mianserin on the severity of psychosis and dyskinesia in the parkinsonian marmoset.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 02-02, Volume: 81

    Topics: Animals; Antidepressive Agents, Second-Generation; Callithrix; Disease Models, Animal; Dose-Response

2018
The effect of mirtazapine on dopaminergic psychosis and dyskinesia in the parkinsonian marmoset.
    Psychopharmacology, 2017, Volume: 234, Issue:6

    Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Behavior, Animal; Callithrix; Dyski

2017
Reversal of haloperidol-induced motor deficits by mianserin and mesulergine in rats.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:1

    Topics: Animals; Antipsychotic Agents; Catalepsy; Dopamine Agonists; Dyskinesia, Drug-Induced; Ergolines; Ha

2011
Acute reversible dyskinesia induced by mirtazapine.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Dyskinesia, Drug-Induced; Humans; Male

2005
Mirtazapine in bupropion-induced dyskinesias: a case report.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:4

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Dyskinesia, D

2006
Does mianserin induce involuntary movements in brain damaged patients?
    International clinical psychopharmacology, 1993,Fall, Volume: 8, Issue:3

    Topics: Aged; Brain Damage, Chronic; Dyskinesia, Drug-Induced; Female; Humans; Mianserin; Movement Disorders

1993
Severe hyperthermia during tetrabenazine therapy for tardive dyskinesia.
    Intensive care medicine, 1998, Volume: 24, Issue:4

    Topics: Anti-Anxiety Agents; Anti-Dyskinesia Agents; Antidepressive Agents, Second-Generation; Antidepressiv

1998
Mirtazapine treats resting tremor, essential tremor, and levodopa-induced dyskinesias.
    Neurology, 1999, Sep-22, Volume: 53, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Dyskinesia, Drug-Induced; Dyskinesias; Female; Humans; Levodopa;

1999
Involuntary movements associated with mianserin treatment. A case report.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Adult; Depressive Disorder; Dyskinesia, Drug-Induced; Female; Humans; Mianserin

1989
Behavioral aspects of serotonin-dopamine interaction in the monkey.
    European journal of pharmacology, 1985, Dec-03, Volume: 118, Issue:3

    Topics: Animals; Chlorocebus aethiops; Cyproheptadine; Dextroamphetamine; Dopamine; Dyskinesia, Drug-Induced

1985