mianserin has been researched along with Drug Overdose in 24 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine." | 5.43 | [Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016) |
| "Mirtazapine appears to be relatively benign in overdose, associated with tachycardia, mild hypertension and mild CNS depression not requiring intervention." | 3.80 | Mirtazapine overdose is unlikely to cause major toxicity. ( Berling, I; Isbister, GK, 2014) |
| "We report the case of intoxication of a 41-year-old female patient suffering from major depression with mirtazapine complicated by severe hypothermia." | 3.70 | Non-fatal mirtazapine overdose. ( Maier, S; Maris, F; Retz, W; Rösler, M, 1998) |
| "In 6 patients, the mirtazapine doses ranged from 10 to 30 times the maximum recommended dose, and there were no serious adverse effects of overdose." | 2.40 | Safety of mirtazapine in overdose. ( Bremner, JD; Walshe, TA; Wingard, P, 1998) |
| "A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine." | 1.43 | [Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016) |
| "Citalopram overdose was more likely to be associated with QT higher than the nomogram compared with the other agents (difference 7." | 1.36 | Evaluation of a QT nomogram for risk assessment after antidepressant overdose. ( Bateman, DN; Graham, A; Gray, J; Howell, C; Waring, WS; Wilson, AD, 2010) |
| "Mirtazapine (Remeron) is a newly approved medication for the treatment of depression." | 1.35 | Outcomes after isolated mirtazapine (Remeron) supratherapeutic ingestions. ( Brown, M; LoVecchio, F; Pizon, A; Riley, B, 2008) |
| "Mirtazapine is a comparatively new antidepressant that selectively blocks central alpha2-adrenergic autoreceptors and postsynaptic 5-HT2 and 5-HT3 receptors, causing reduced neuronal norepinephrine and serotonin reuptake." | 1.34 | Lack of significant toxicity after mirtazapine overdose: a five-year review of cases admitted to a regional toxicology unit. ( Bateman, DN; Good, AM; Waring, WS, 2007) |
| "Citalopram was associated with a significantly longer QT interval on ECG recording (p < 0." | 1.32 | Comparative toxicity of citalopram and the newer antidepressants after overdose. ( Bateman, DN; Dhaun, N; Good, AM; Kelly, CA; Laing, WJ; Strachan, FE, 2004) |
| "Amitriptyline was studied in greater detail and caused a dose-related (0." | 1.30 | Acute lung failure induced by tricyclic antidepressants. ( Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A, 1997) |
| "Mirtazapine seems to be a safe compound in overdose." | 1.30 | Suicide attempts with mirtazapine overdose without complications. ( Holzbach, R; Jahn, H; Mähne, C; Pajonk, FG, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nedahl, M | 1 |
| Johansen, SS | 1 |
| Linnet, K | 1 |
| Berling, I | 1 |
| Isbister, GK | 1 |
| Matsumoto, H | 1 |
| Ohnishi, M | 1 |
| Takegawa, R | 1 |
| Hirose, T | 1 |
| Hattori, Y | 1 |
| Shimazu, T | 1 |
| de Witte, LD | 1 |
| Dekker, D | 1 |
| Veraart, J | 1 |
| Kromkamp, M | 1 |
| Kaasjager, K | 1 |
| Vinkers, CH | 1 |
| Garg, U | 1 |
| Frazee, C | 1 |
| Johnson, L | 1 |
| Turner, JW | 1 |
| Waring, WS | 2 |
| Graham, A | 1 |
| Gray, J | 1 |
| Wilson, AD | 1 |
| Howell, C | 1 |
| Bateman, DN | 4 |
| Garlipp, P | 1 |
| Brüggemann, BR | 1 |
| Machleidt, W | 1 |
| Langford, NJ | 1 |
| Ferner, RE | 1 |
| Patel, H | 1 |
| Munyame, C | 1 |
| Hamlyn, AN | 1 |
| Chick, J | 1 |
| Good, AM | 3 |
| Kelly, CA | 2 |
| Masterton, G | 1 |
| Dhaun, N | 1 |
| Laing, WJ | 1 |
| Strachan, FE | 1 |
| Kuliwaba, A | 1 |
| Altun, G | 1 |
| LoVecchio, F | 1 |
| Riley, B | 1 |
| Pizon, A | 1 |
| Brown, M | 1 |
| Hoes, MJ | 1 |
| Zeijpveld, JH | 1 |
| Montgomery, SA | 1 |
| Gerritsen, AW | 1 |
| Dahlin, KL | 1 |
| Lâstbom, L | 1 |
| Blomgren, B | 1 |
| Ryrfeldt, A | 1 |
| Bremner, JD | 1 |
| Wingard, P | 1 |
| Walshe, TA | 1 |
| Holzbach, R | 1 |
| Jahn, H | 1 |
| Pajonk, FG | 1 |
| Mähne, C | 1 |
| Retz, W | 1 |
| Maier, S | 1 |
| Maris, F | 1 |
| Rösler, M | 1 |
| Velazquez, C | 1 |
| Carlson, A | 1 |
| Stokes, KA | 1 |
| Leikin, JB | 1 |
| Raja, M | 1 |
| Azzoni, A | 1 |
| Namera, A | 1 |
3 reviews available for mianserin and Drug Overdose
| Article | Year |
|---|---|
Safety of mirtazapine: a review.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Rel | 1995 |
Safety of mirtazapine in overdose.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Biopharmaceutics; Charcoal; Child, Preschool; Clinica | 1998 |
[Practical analysis of toxic substances useful of clinical toxicology -2- tricyclic and tetracyclic antidepressants].
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chromatography, Ion Exchange; Drug O | 2002 |
21 other studies available for mianserin and Drug Overdose
| Article | Year |
|---|---|
Reference Brain/Blood Concentrations of Citalopram, Duloxetine, Mirtazapine and Sertraline.
Topics: Antidepressive Agents; Brain; Calibration; Cause of Death; Chromatography, Liquid; Citalopram; Drug | 2018 |
Mirtazapine overdose is unlikely to cause major toxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Critical Care; Databases, Factual | 2014 |
Effect of lipid emulsion during resuscitation of a patient with cardiac arrest after overdose of chlorpromazine and mirtazapine.
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cardiopulmonary Resuscitation; Chlorpromazin | 2015 |
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans; | 2016 |
A fatal case involving extremely high levels of ethylene glycol without elevation of its metabolites or crystalluria.
Topics: Antidepressive Agents; Bupropion; Drug Overdose; Ethylene Glycol; Forensic Toxicology; Glycolates; G | 2009 |
Evaluation of a QT nomogram for risk assessment after antidepressant overdose.
Topics: Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Drug Overdose; Electrocardiography; Female; | 2010 |
A non-fatal mirtazapine overdose in a suicide attempt.
Topics: Adult; Antidepressive Agents, Tricyclic; Drug Overdose; Female; Humans; Mianserin; Mirtazapine; Suic | 2003 |
Mirtazepine overdose and miosis.
Topics: Adult; Antidepressive Agents, Tricyclic; Drug Overdose; Female; Humans; Mianserin; Miosis; Mirtazapi | 2003 |
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Ove | 2004 |
Comparative toxicity of citalopram and the newer antidepressants after overdose.
Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Dr | 2004 |
Non-lethal mirtazapine overdose with rhabdomyolysis.
Topics: Adult; Antidepressive Agents, Tricyclic; Depression; Drug Overdose; Humans; Male; Mianserin; Mirtaza | 2005 |
Planned complex suicide: report of three cases.
Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Drug Ov | 2006 |
Lack of significant toxicity after mirtazapine overdose: a five-year review of cases admitted to a regional toxicology unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Drug Overdose; Female; | 2007 |
Outcomes after isolated mirtazapine (Remeron) supratherapeutic ingestions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Child; Drug Overdose; | 2008 |
First report of mirtazapine overdose.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Coma; Depressive Dis | 1996 |
Safety in overdose of mirtazapine: a case report.
Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety; Confusion; Depressive Disorder; Dothiepin; Drug Ov | 1997 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose- | 1997 |
Suicide attempts with mirtazapine overdose without complications.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Overdose; Female; Humans; Mianser | 1998 |
Non-fatal mirtazapine overdose.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Overdose; Female; Humans; Hypothe | 1998 |
Relative safety of mirtazapine overdose.
Topics: Adult; Antidepressive Agents, Tricyclic; Cathartics; Charcoal; Drug Overdose; Electrocardiography; H | 2001 |
Mirtazapine overdose with benign outcome.
Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Drug Overdose; Female; Humans; Mianserin; Middle | 2002 |