mianserin has been researched along with Diabetic Neuropathies in 3 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mianserin was given in the fixed dosage of 60 mg per day, whereas the dose of imipramine was adjusted to yield the optimal plasma concentration of imipramine plus desipramine of 400-600 nmol." | 2.67 | Lack of effect of mianserin on the symptoms of diabetic neuropathy. ( Beck-Nielsen, H; Brøsen, K; Gram, LF; Grodum, E; Sindrup, SH; Skjold, T; Tuxen, C, 1992) |
| "The effect of mianserin on hyperalgesia occurring in connection with peripheral diabetic neuropathy was examined using the Randall-Selitto (mechanical nociceptive stimulus), Hargreaves (thermal nociceptive stimulus), and cold-plate (4°C, thermal nociceptive stimulus) tests." | 1.42 | Antihyperalgesic and antiallodynic effects of mianserin on diabetic neuropathic pain: a study on mechanism of action. ( Can, ÖD; Demir Özkay, Ü; Öztürk, Y; Üçel, Uİ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Üçel, Uİ | 1 |
| Can, ÖD | 1 |
| Demir Özkay, Ü | 1 |
| Öztürk, Y | 1 |
| Sindrup, SH | 1 |
| Tuxen, C | 1 |
| Gram, LF | 1 |
| Grodum, E | 1 |
| Skjold, T | 1 |
| Brøsen, K | 1 |
| Beck-Nielsen, H | 1 |
| Young, RJ | 1 |
| Clarke, BF | 1 |
2 trials available for mianserin and Diabetic Neuropathies
| Article | Year |
|---|---|
Lack of effect of mianserin on the symptoms of diabetic neuropathy.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Desipramine; Diabetic Neuropathies; Double-Blind Meth | 1992 |
Pain relief in diabetic neuropathy: the effectiveness of imipramine and related drugs.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Clonazepam; Diabetic Neuropathies; Double-Blin | 1985 |
1 other study available for mianserin and Diabetic Neuropathies
| Article | Year |
|---|---|
Antihyperalgesic and antiallodynic effects of mianserin on diabetic neuropathic pain: a study on mechanism of action.
Topics: Analgesics; Animals; Catecholamines; Diabetic Neuropathies; Hyperalgesia; Male; Mianserin; Neuralgia | 2015 |