mianserin has been researched along with Dementia in 12 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| " (1) The secondary analyses presented here suggest that there would be value in carrying out a placebo-controlled trial of the clinical effectiveness and cost-effectiveness of mirtazapine in the management of Behavioural and Psychological Symptoms of Dementia." | 9.17 | Study of the use of antidepressants for depression in dementia: the HTA-SADD trial--a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine. ( Baldwin, R; Ballard, C; Banerjee, S; Bentham, P; Burns, A; Dewey, M; Fox, C; Hellier, J; Holmes, C; Katona, C; Knapp, M; Lawton, C; Lindesay, J; Livingston, G; McCrae, N; Moniz-Cook, E; Murray, J; Nurock, S; O'Brien, J; Orrell, M; Poppe, M; Romeo, R; Thomas, A; Walwyn, R; Wilson, K, 2013) |
| "To evaluate the cost-effectiveness of sertraline and mirtazapine compared with placebo for depression in dementia." | 9.17 | Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial. ( Baldwin, R; Ballard, C; Banerjee, S; Bentham, P; Burns, A; Dewey, M; Fox, C; Hellier, J; Holmes, C; Katona, C; Knapp, M; Lawton, C; Lindesay, J; Livingston, G; McCrae, N; Moniz-Cook, E; Murray, J; Nurock, S; O'Brien, J; Poppe, M; Romeo, R; Thomas, A; Walwyn, R; Wilson, K, 2013) |
| " This randomised, double-blind study compared the efficacy and tolerability of citalopram and mianserin in 336 elderly, depressed patients with or without dementia." | 9.09 | A randomised, double-blind comparison of the efficacy and safety of citalopram compared to mianserin in elderly, depressed patients with or without mild to moderate dementia. ( Augusto De Mendonça Lima, C; Eglin, M; Godderis, J; Karlsson, I; Nygaard, H; Simányi, M; Taal, M, 2000) |
| " (1) The secondary analyses presented here suggest that there would be value in carrying out a placebo-controlled trial of the clinical effectiveness and cost-effectiveness of mirtazapine in the management of Behavioural and Psychological Symptoms of Dementia." | 5.17 | Study of the use of antidepressants for depression in dementia: the HTA-SADD trial--a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine. ( Baldwin, R; Ballard, C; Banerjee, S; Bentham, P; Burns, A; Dewey, M; Fox, C; Hellier, J; Holmes, C; Katona, C; Knapp, M; Lawton, C; Lindesay, J; Livingston, G; McCrae, N; Moniz-Cook, E; Murray, J; Nurock, S; O'Brien, J; Orrell, M; Poppe, M; Romeo, R; Thomas, A; Walwyn, R; Wilson, K, 2013) |
| "To evaluate the cost-effectiveness of sertraline and mirtazapine compared with placebo for depression in dementia." | 5.17 | Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial. ( Baldwin, R; Ballard, C; Banerjee, S; Bentham, P; Burns, A; Dewey, M; Fox, C; Hellier, J; Holmes, C; Katona, C; Knapp, M; Lawton, C; Lindesay, J; Livingston, G; McCrae, N; Moniz-Cook, E; Murray, J; Nurock, S; O'Brien, J; Poppe, M; Romeo, R; Thomas, A; Walwyn, R; Wilson, K, 2013) |
| " This randomised, double-blind study compared the efficacy and tolerability of citalopram and mianserin in 336 elderly, depressed patients with or without dementia." | 5.09 | A randomised, double-blind comparison of the efficacy and safety of citalopram compared to mianserin in elderly, depressed patients with or without mild to moderate dementia. ( Augusto De Mendonça Lima, C; Eglin, M; Godderis, J; Karlsson, I; Nygaard, H; Simányi, M; Taal, M, 2000) |
| "The prevalence of insomnia increases with age and affects up to 35% of community-dwelling adults with dementia." | 2.45 | Non-pharmacologic treatment of insomnia in persons with dementia. ( Darvishi, R; Kunik, ME; Shub, D, 2009) |
| "Of these disorders, depression is the most accessible of these to pharmacological treatment; agitation, however, raises the institutional problem." | 1.28 | Psychiatrists and Alzheimer's disease. ( Cazas, A; Flame, E; Ginestet, D, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bucki, A | 1 |
| Marcinkowska, M | 1 |
| Śniecikowska, J | 1 |
| Zagórska, A | 1 |
| Jamrozik, M | 1 |
| Pawłowski, M | 1 |
| Głuch-Lutwin, M | 1 |
| Siwek, A | 1 |
| Jakubczyk, M | 1 |
| Pytka, K | 1 |
| Jastrzębska-Więsek, M | 1 |
| Partyka, A | 1 |
| Wesołowska, A | 1 |
| Mierzejewski, P | 1 |
| Kołaczkowski, M | 1 |
| Lanctôt, KL | 1 |
| Herrmann, N | 1 |
| Banerjee, S | 3 |
| Hellier, J | 3 |
| Romeo, R | 3 |
| Dewey, M | 3 |
| Knapp, M | 3 |
| Ballard, C | 3 |
| Baldwin, R | 3 |
| Bentham, P | 3 |
| Fox, C | 3 |
| Holmes, C | 3 |
| Katona, C | 3 |
| Lawton, C | 3 |
| Lindesay, J | 3 |
| Livingston, G | 3 |
| McCrae, N | 3 |
| Moniz-Cook, E | 3 |
| Murray, J | 3 |
| Nurock, S | 3 |
| Orrell, M | 2 |
| O'Brien, J | 3 |
| Poppe, M | 3 |
| Thomas, A | 3 |
| Walwyn, R | 3 |
| Wilson, K | 3 |
| Burns, A | 3 |
| Shub, D | 1 |
| Darvishi, R | 1 |
| Kunik, ME | 1 |
| Berilgen, MS | 1 |
| Brodaty, H | 1 |
| Sepehry, AA | 1 |
| Lee, PE | 1 |
| Hsiung, GY | 1 |
| Jacova, C | 1 |
| Camargos, EF | 1 |
| Oliveira, LF | 1 |
| Boaventura, TD | 1 |
| Quintas, JL | 1 |
| Karlsson, I | 1 |
| Godderis, J | 1 |
| Augusto De Mendonça Lima, C | 1 |
| Nygaard, H | 1 |
| Simányi, M | 1 |
| Taal, M | 1 |
| Eglin, M | 1 |
| Cazas, A | 1 |
| Flame, E | 1 |
| Ginestet, D | 1 |
2 reviews available for mianserin and Dementia
| Article | Year |
|---|---|
Non-pharmacologic treatment of insomnia in persons with dementia.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Antidepressive Agents, Tricyclic; Circadian Rhyth | 2009 |
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Do | 2011 |
4 trials available for mianserin and Dementia
| Article | Year |
|---|---|
Study of the use of antidepressants for depression in dementia: the HTA-SADD trial--a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine.
Topics: Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Dementia; Depr | 2013 |
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Do | 2011 |
Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial.
Topics: Antidepressive Agents; Caregivers; Cost-Benefit Analysis; Dementia; Depression; Health Care Costs; H | 2013 |
A randomised, double-blind comparison of the efficacy and safety of citalopram compared to mianserin in elderly, depressed patients with or without mild to moderate dementia.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Citalopram; Dementia; Depressive | 2000 |
7 other studies available for mianserin and Dementia
| Article | Year |
|---|---|
Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD).
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzoxazoles; Dementia; Dizocilpine Maleate; Dose-R | 2020 |
Mirtazapine for agitation in dementia: moving forward.
Topics: Antidepressive Agents; Dementia; Humans; Mianserin; Mirtazapine | 2021 |
Delirium associated with mianserin in demented patients.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Del | 2010 |
Antidepressant treatment in Alzheimer's disease.
Topics: Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Double-B | 2011 |
Stay the course--is it justified?
Topics: Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Female; Humans; Male; Menta | 2012 |
Mianserin for the treatment of sleep disorders in patients with dementia: a retrospective open-label study.
Topics: Aged; Aged, 80 and over; Dementia; Humans; Hypnotics and Sedatives; Mianserin; Retrospective Studies | 2012 |
Psychiatrists and Alzheimer's disease.
Topics: Alzheimer Disease; Circadian Rhythm; Cognition; Dementia; Depression; Diagnosis, Differential; Human | 1989 |