Page last updated: 2024-10-31

mianserin and Delirium of Mixed Origin

mianserin has been researched along with Delirium of Mixed Origin in 13 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Research Excerpts

ExcerptRelevanceReference
" The authors administered the tetracyclic antidepressant mianserin to aged patients with delirium to examine its efficacy in delirium."9.08Efficacy of mianserin on symptoms of delirium in the aged: an open trial study. ( Isse, K; Tanaka, K; Toru, M; Uchiyama, M, 1996)
"Sixty-six patients (47 men, 19 women, mean age 65 years) with delirium were treated with mianserin (10-60 mg/day) or haloperidol (2-6 mg/day) at Kurume University Hospital."9.08Does plasma free-3-methoxy-4-hydroxyphenyl(ethylene)glycol increase in the delirious state? A comparison of the effects of mianserin and haloperidol on delirium. ( Nakamura, J; Nakazawa, Y; Uchimura, N; Yamada, S, 1997)
"Mianserin (10-60 mg), haloperidol (2-6 mg) and oxypertine (20-60 mg) were administered once before bedtime in patients with delirium in Kurume University Hospital."9.07[Effects of mianserin hydrochloride on delirium: comparison with the effects of oxypertine and haloperidol]. ( Nakamura, J; Nakazawa, Y; Uchimura, N; Yamada, S, 1994)
"We present the cases of two elderly patients with intermittent long-term tramadol intake against chronic back pain."7.73Unrecognised long-lasting tramadol-induced delirium in two elderly patients. A case report. ( Dätwyler, S; Eschen, A; Künig, G; Schreiter Gasser, U, 2006)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."5.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"Mirtazapine has demonstrated superior tolerability to the tricyclic antidepressants, primarily on account of its relative absence of anticholinergic, adrenergic and serotonin-related adverse effects."5.31Occurrence of mirtazapine-induced delirium in organic brain disorder. ( Bailer, U; Fischer, P; Kasper, S; Küfferle, B; Stastny, J, 2000)
" The authors administered the tetracyclic antidepressant mianserin to aged patients with delirium to examine its efficacy in delirium."5.08Efficacy of mianserin on symptoms of delirium in the aged: an open trial study. ( Isse, K; Tanaka, K; Toru, M; Uchiyama, M, 1996)
"Sixty-six patients (47 men, 19 women, mean age 65 years) with delirium were treated with mianserin (10-60 mg/day) or haloperidol (2-6 mg/day) at Kurume University Hospital."5.08Does plasma free-3-methoxy-4-hydroxyphenyl(ethylene)glycol increase in the delirious state? A comparison of the effects of mianserin and haloperidol on delirium. ( Nakamura, J; Nakazawa, Y; Uchimura, N; Yamada, S, 1997)
"Mianserin (10-60 mg), haloperidol (2-6 mg) and oxypertine (20-60 mg) were administered once before bedtime in patients with delirium in Kurume University Hospital."5.07[Effects of mianserin hydrochloride on delirium: comparison with the effects of oxypertine and haloperidol]. ( Nakamura, J; Nakazawa, Y; Uchimura, N; Yamada, S, 1994)
"We present the cases of two elderly patients with intermittent long-term tramadol intake against chronic back pain."3.73Unrecognised long-lasting tramadol-induced delirium in two elderly patients. A case report. ( Dätwyler, S; Eschen, A; Künig, G; Schreiter Gasser, U, 2006)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."1.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"Mirtazapine has demonstrated superior tolerability to the tricyclic antidepressants, primarily on account of its relative absence of anticholinergic, adrenergic and serotonin-related adverse effects."1.31Occurrence of mirtazapine-induced delirium in organic brain disorder. ( Bailer, U; Fischer, P; Kasper, S; Küfferle, B; Stastny, J, 2000)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's5 (38.46)18.2507
2000's3 (23.08)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uenishi, S1
Takahashi, S1
Nakayama, Y1
Hiwatani, Y1
Nakane, S1
Tsuji, T1
Ukai, S1
Sockalingam, S1
Sheehan, K1
Feld, JJ1
Shah, H1
de Witte, LD1
Dekker, D1
Veraart, J1
Kromkamp, M1
Kaasjager, K1
Vinkers, CH1
Berilgen, MS1
Künig, G1
Dätwyler, S1
Eschen, A1
Schreiter Gasser, U1
Ito, H1
Harada, D1
Hayashida, K1
Ishino, H1
Nakayama, K1
Bonne, O1
Shalev, AY1
Bloch, M1
Nakamura, J2
Uchimura, N2
Yamada, S2
Nakazawa, Y2
Uchiyama, M1
Tanaka, K1
Isse, K1
Toru, M1
Bailer, U1
Fischer, P1
Küfferle, B1
Stastny, J1
Kasper, S1
Koponen, H1
Honkonen, S1
Partanen, J1
Riekkinen, PJ1
Fisch, RZ1
Alexandrowitz, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Frequency of Anxiety and Depression in Chronic Hepatitis C Patients Recieving Direct-Acting Antiviral Agents.[NCT03894696]200 participants (Anticipated)Observational2019-08-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for mianserin and Delirium of Mixed Origin

ArticleYear
Delirium associated with mianserin.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:2

    Topics: Aged; Aging; Delirium; Depressive Disorder; Female; Humans; Male; Mianserin; Middle Aged; Prevalence

1995
[Effects of mianserin hydrochloride on delirium: comparison with the effects of oxypertine and haloperidol].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1994, Volume: 14, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Female; Haloperidol; Humans; Male; M

1994
Efficacy of mianserin on symptoms of delirium in the aged: an open trial study.
    Progress in neuro-psychopharmacology & biological psychiatry, 1996, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Delirium; Female; Humans; Male; M

1996
Does plasma free-3-methoxy-4-hydroxyphenyl(ethylene)glycol increase in the delirious state? A comparison of the effects of mianserin and haloperidol on delirium.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:3

    Topics: Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Delirium; Female; Haloperidol;

1997

Other Studies

9 other studies available for mianserin and Delirium of Mixed Origin

ArticleYear
A case of autoimmune autonomic ganglionopathy with prolonged delirium.
    Asian journal of psychiatry, 2019, Volume: 39

    Topics: Adrenergic alpha-Antagonists; Aged; Antipsychotic Agents; Autoimmune Diseases; Autonomic Nervous Sys

2019
Psychiatric care during hepatitis C treatment: the changing role of psychiatrists in the era of direct-acting antivirals.
    The American journal of psychiatry, 2015, Volume: 172, Issue:6

    Topics: Antidepressive Agents; Antiviral Agents; Citalopram; Comorbidity; Cooperative Behavior; Delirium; De

2015
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
    Nederlands tijdschrift voor geneeskunde, 2016, Volume: 160

    Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans;

2016
Delirium associated with mianserin in demented patients.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Del

2010
Unrecognised long-lasting tramadol-induced delirium in two elderly patients. A case report.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Delirium; Drug I

2006
[Psychiatry and sleep disorders--delirium].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2006, Volume: 108, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Female; Haloperidol; Humans; I

2006
Occurrence of mirtazapine-induced delirium in organic brain disorder.
    International clinical psychopharmacology, 2000, Volume: 15, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Delirium; Depressive Disorder, Major; Fem

2000
Epileptic attack, delirium, and periodic complexes in the EEG during mianserin treatment.
    Journal of neurology, neurosurgery, and psychiatry, 1991, Volume: 54, Issue:4

    Topics: Aged; Creutzfeldt-Jakob Syndrome; Delirium; Depressive Disorder; Diagnosis, Differential; Electroenc

1991
Delirium in a patient treated with mianserin.
    British medical journal (Clinical research ed.), 1988, Jan-09, Volume: 296, Issue:6615

    Topics: Aged; Delirium; Female; Humans; Mianserin

1988