Page last updated: 2024-10-31

mianserin and Daytime Sleepiness

mianserin has been researched along with Daytime Sleepiness in 6 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to conduct a naturalistic, open-label examination of the efficacy and tolerability of mirtazapine (a medication with both serotonergic and noradrenergic properties) in the treatment of associated symptoms of autism and other pervasive developmental disorders (PDDs)."5.09A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders. ( Guenin, KD; Kohn, AE; McDougle, CJ; Posey, DJ; Swiezy, NB, 2001)
"Insomnia and daytime sleepiness are often associated with depression."2.42Daytime sleepiness and insomnia as correlates of depression. ( Fava, M, 2004)
"In an animal model of central apnea the use of mirtazapine produced a significant reduction of apneas."1.32Effectiveness of mirtazapine in the treatment of sleep apnea/hypopnea syndrome (SAHS). ( Castillo, JL; Guilleminault, C; Menendez, P; Segovia, L, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brunette, MF1
Akerman, SC1
Dawson, R1
O'Keefe, CD1
Green, AI1
Davis, MP1
Kirkova, J1
Lagman, R1
Walsh, D1
Karafa, M1
Castillo, JL1
Menendez, P1
Segovia, L1
Guilleminault, C1
Fava, M1
Han, C1
Pae, CU1
Lee, BH1
Ko, YH1
Masand, PS1
Patkar, AA1
Joe, SH1
Jung, IK1
Posey, DJ1
Guenin, KD1
Kohn, AE1
Swiezy, NB1
McDougle, CJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Music to Improve Sleep Quality in Adults With Depression and Insomnia: a Randomized Controlled Trial Using Mixed Methods[NCT03676491]112 participants (Actual)Interventional2018-05-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for mianserin and Daytime Sleepiness

ArticleYear
Daytime sleepiness and insomnia as correlates of depression.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 16

    Topics: Antidepressive Agents; Benzhydryl Compounds; Bupropion; Comorbidity; Depressive Disorder; Disorders

2004

Trials

2 trials available for mianserin and Daytime Sleepiness

ArticleYear
Venlafaxine versus mirtazapine in the treatment of undifferentiated somatoform disorder: a 12-week prospective, open-label, randomized, parallel-group trial.
    Clinical drug investigation, 2008, Volume: 28, Issue:4

    Topics: Adult; Antidepressive Agents; Cyclohexanols; Diagnostic and Statistical Manual of Mental Disorders;

2008
A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders.
    Journal of child and adolescent psychopharmacology, 2001,Fall, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aggression; Antidepressive Agents, Tricyclic; Anxiety Disorders; Appetite; Autist

2001

Other Studies

3 other studies available for mianserin and Daytime Sleepiness

ArticleYear
An open-label pilot study of quetiapine plus mirtazapine for heavy drinkers with alcohol use disorder.
    Alcohol (Fayetteville, N.Y.), 2016, Volume: 53

    Topics: Adrenergic alpha-Antagonists; Adult; Alcohol Drinking; Alcohol-Related Disorders; Antipsychotic Agen

2016
Intolerance to mirtazapine in advanced cancer.
    Journal of pain and symptom management, 2011, Volume: 42, Issue:3

    Topics: Aged; Antidepressive Agents; Depressive Disorder; Disorders of Excessive Somnolence; Female; Humans;

2011
Effectiveness of mirtazapine in the treatment of sleep apnea/hypopnea syndrome (SAHS).
    Sleep medicine, 2004, Volume: 5, Issue:5

    Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Continuous Positive Airway Pressure; Disorders

2004