mianserin has been researched along with Colonic Diseases, Functional in 5 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alda Díez, M | 1 |
| Espuelas Monge, M | 1 |
| García-Campayo, J | 1 |
| Tanum, L | 3 |
| Malt, UF | 3 |
| Bråtveit-Johansen, K | 1 |
| Thomas, SG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia[NCT00547703] | 5 participants (Actual) | Interventional | 2008-02-29 | Terminated (stopped due to Not enough participants - only 5 since the study started) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient would answer yes or no to a simple question asking whether they had adequate relief of abdominal pain or discomfort. This was measured at weeks 2,4 and 8 of the study but only week 8 was reported. What is being reported is the number of participants who answered yes. (NCT00547703)
Timeframe: 8 weeks
| Intervention | participants (Number) |
|---|---|
| Nortriptyline | 2 |
| Placebo | 1 |
3 trials available for mianserin and Colonic Diseases, Functional
| Article | Year |
|---|---|
A new pharmacologic treatment of functional gastrointestinal disorder. A double-blind placebo-controlled study with mianserin.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Colonic Diseases, Functional; Dou | 1996 |
Fenfluramine challenge test predicts outcome in pharmacological treatment of patients with functional gastrointestinal disorder.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Colonic Diseases, Functional; Double-Blind Me | 1999 |
Personality traits predict treatment outcome with an antidepressant in patients with functional gastrointestinal disorder.
Topics: Adult; Aged; Aggression; Antidepressive Agents, Second-Generation; Colonic Diseases, Functional; Dys | 2000 |
2 other studies available for mianserin and Colonic Diseases, Functional
| Article | Year |
|---|---|
[Dolichocolon as unwanted effect of treatment with the anti-depressant mirtazapine].
Topics: Adult; Antidepressive Agents, Tricyclic; Colon; Colonic Diseases, Functional; Female; Humans; Mianse | 2004 |
Irritable bowel syndrome and mirtazapine.
Topics: Adult; Antidepressive Agents, Tricyclic; Colonic Diseases, Functional; Drug Administration Schedule; | 2000 |