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mianserin and Cognition Disorders

mianserin has been researched along with Cognition Disorders in 9 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"We aimed to evaluate predictors and mediators of enhancing effect of adjunctive mirtazapine on cognition in schizophrenia."9.17Predictors and mediators of add-on mirtazapine-induced cognitive enhancement in schizophrenia--a path model investigation. ( Burkin, M; Chukhin, E; Joffe, G; Joffe, M; Stenberg, JH; Terevnikov, V; Tiihonen, J, 2013)
"This preliminary study aimed to determine if adding mirtazapine to risperidone might improve negative and cognitive symptoms in schizophrenia."9.15Mirtazapine augmentation enhances cognitive and reduces negative symptoms in schizophrenia patients treated with risperidone: a randomized controlled trial. ( Cho, SJ; Choi, TK; Kim, B; Kim, YW; Lee, JE; Lee, KS; Lee, SH; Suh, S; Yook, K; Yook, KH, 2011)
" In a double-blind placebo-controlled study we examined the effect of add-on mianserin (15 mg/day), an agent with marked 5-HT2A antagonism, on cognitive functioning in 30 chronic hospitalized DSM-IV schizophrenia patients stabilized on typical antipsychotics."9.10Effect of the 5-HT2 antagonist mianserin on cognitive dysfunction in chronic schizophrenia patients: an add-on, double-blind placebo-controlled study. ( Fuchs, C; Gonopolsky, I; Koren, D; Poyurovsky, M; Schneidman, M; Weizman, A; Weizman, R, 2003)
"We aimed to evaluate predictors and mediators of enhancing effect of adjunctive mirtazapine on cognition in schizophrenia."5.17Predictors and mediators of add-on mirtazapine-induced cognitive enhancement in schizophrenia--a path model investigation. ( Burkin, M; Chukhin, E; Joffe, G; Joffe, M; Stenberg, JH; Terevnikov, V; Tiihonen, J, 2013)
"This preliminary study aimed to determine if adding mirtazapine to risperidone might improve negative and cognitive symptoms in schizophrenia."5.15Mirtazapine augmentation enhances cognitive and reduces negative symptoms in schizophrenia patients treated with risperidone: a randomized controlled trial. ( Cho, SJ; Choi, TK; Kim, B; Kim, YW; Lee, JE; Lee, KS; Lee, SH; Suh, S; Yook, K; Yook, KH, 2011)
" In a double-blind placebo-controlled study we examined the effect of add-on mianserin (15 mg/day), an agent with marked 5-HT2A antagonism, on cognitive functioning in 30 chronic hospitalized DSM-IV schizophrenia patients stabilized on typical antipsychotics."5.10Effect of the 5-HT2 antagonist mianserin on cognitive dysfunction in chronic schizophrenia patients: an add-on, double-blind placebo-controlled study. ( Fuchs, C; Gonopolsky, I; Koren, D; Poyurovsky, M; Schneidman, M; Weizman, A; Weizman, R, 2003)
"Mirtazapine adjunction was well tolerated and induced a significant improvement in cognitive performance, as measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS; Randolph, 1998) total score and by the subscales for immediate and delayed memory (p<."2.73Add-on mirtazapine enhances effects on cognition in schizophrenic patients under stabilized treatment with clozapine. ( Biondi, M; Delle Chiaie, R; Fiorentini, S; Salviati, M, 2007)
"Treatment with mirtazapine 30 mg orally daily and mefloquine hydrochloride 250 mg orally for three days, then 250 mg weekly, was initiated."1.38Mirtazapine and mefloquine therapy for progressive multifocal leukoencephalopathy in a patient infected with human immunodeficiency virus. ( Jett, RA; Moenster, RP, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Loyaga-Rendon, RY1
Taylor, DO1
Koval, CE1
Messer, T1
Cho, SJ1
Yook, K1
Kim, B1
Choi, TK1
Lee, KS1
Kim, YW1
Lee, JE1
Suh, S1
Yook, KH1
Lee, SH1
Moenster, RP1
Jett, RA1
Stenberg, JH1
Terevnikov, V1
Joffe, M1
Tiihonen, J1
Chukhin, E1
Burkin, M1
Joffe, G1
Poyurovsky, M1
Koren, D1
Gonopolsky, I1
Schneidman, M1
Fuchs, C1
Weizman, A1
Weizman, R1
Schillerstrom, JE1
Seaman, JS1
Delle Chiaie, R1
Salviati, M1
Fiorentini, S1
Biondi, M1
Thompson, PJ1
Trimble, MR1

Trials

4 trials available for mianserin and Cognition Disorders

ArticleYear
Mirtazapine augmentation enhances cognitive and reduces negative symptoms in schizophrenia patients treated with risperidone: a randomized controlled trial.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cognition Disorders; Double-Blind Met

2011
Predictors and mediators of add-on mirtazapine-induced cognitive enhancement in schizophrenia--a path model investigation.
    Neuropharmacology, 2013, Volume: 64

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Antipsychotic Agents; Cognition; Cognition Disorders

2013
Effect of the 5-HT2 antagonist mianserin on cognitive dysfunction in chronic schizophrenia patients: an add-on, double-blind placebo-controlled study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2003, Volume: 13, Issue:2

    Topics: Adult; Analysis of Variance; Chi-Square Distribution; Chronic Disease; Cognition Disorders; Double-B

2003
Add-on mirtazapine enhances effects on cognition in schizophrenic patients under stabilized treatment with clozapine.
    Experimental and clinical psychopharmacology, 2007, Volume: 15, Issue:6

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antipsychotic Agents; Brief Psychiatric R

2007

Other Studies

5 other studies available for mianserin and Cognition Disorders

ArticleYear
Progressive multifocal leukoencephalopathy in a heart transplant recipient following rituximab therapy for antibody-mediated rejection.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2013, Volume: 13, Issue:4

    Topics: Antibodies, Monoclonal, Murine-Derived; Cognition Disorders; Fatal Outcome; Graft Rejection; Heart F

2013
[Cognitive dysfunction in major depression].
    MMW Fortschritte der Medizin, 2015, Sep-24, Volume: 157, Issue:16

    Topics: Attention; Cognition Disorders; Depressive Disorder, Major; Drug Therapy, Combination; Executive Fun

2015
Mirtazapine and mefloquine therapy for progressive multifocal leukoencephalopathy in a patient infected with human immunodeficiency virus.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Mar-15, Volume: 69, Issue:6

    Topics: Cognition Disorders; Histamine H1 Antagonists; HIV Infections; Humans; JC Virus; Leukoencephalopathy

2012
Modafinil augmentation of mirtazapine in a failure-to-thrive geriatric inpatient.
    International journal of psychiatry in medicine, 2002, Volume: 32, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Benzhydryl Compounds; Cachexia; Central Nervous System Stimu

2002
Non-MAOI antidepressant drugs and cognitive functions: a review.
    Psychological medicine, 1982, Volume: 12, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Cognition; Cognition Disorders; Depressive Disorder; Dose-Resp

1982