Page last updated: 2024-10-31

mianserin and Chronic Illness

mianserin has been researched along with Chronic Illness in 43 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Research Excerpts

ExcerptRelevanceReference
" Mirtazapine has a prophylactic and ibuprofen an acute effect in tension-type headache."9.12Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache. ( Ashina, S; Bendtsen, L; Buchgreitz, L; Jensen, R, 2007)
" In a double-blind placebo-controlled study we examined the effect of add-on mianserin (15 mg/day), an agent with marked 5-HT2A antagonism, on cognitive functioning in 30 chronic hospitalized DSM-IV schizophrenia patients stabilized on typical antipsychotics."9.10Effect of the 5-HT2 antagonist mianserin on cognitive dysfunction in chronic schizophrenia patients: an add-on, double-blind placebo-controlled study. ( Fuchs, C; Gonopolsky, I; Koren, D; Poyurovsky, M; Schneidman, M; Weizman, A; Weizman, R, 2003)
"The reduction of pain by two antidepressants, clomipramine and mianserin, was, in this study on 253 patients with chronic idiopathic pain syndrome, found to be not better than a placebo when all patients were compared independently of the classification of pain."9.06Clomipramine and mianserin in chronic idiopathic pain syndrome. A placebo controlled study. ( Bech, P; Hansen, HJ; Langemark, M; Loldrup, D; Olesen, J, 1989)
"The effects of acute, systemic administration of amitriptyline, duloxetine and mirtazapine (antidepressant drugs that variously affect extracellular noradrenaline and serotonin levels) and the selective serotonin reuptake inhibitor (SSRI) citalopram were compared in rat models of experimental pain."7.73Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain. ( Blackburn-Munro, G; Bomholt, SF; Mikkelsen, JD, 2005)
"To evaluate the safety, tolerability and efficacy of mirtazapine in patients with the primary diagnosis of chronic pain and concomitant depression in an open post-marketing surveillance study."7.73The effect of mirtazapine in patients with chronic pain and concomitant depression. ( Freynhagen, R; Lipfert, P; Muth-Selbach, U; Stevens, MF; Tölle, TR; von Giesen, HJ; Zacharowski, K, 2006)
"We present the cases of two elderly patients with intermittent long-term tramadol intake against chronic back pain."7.73Unrecognised long-lasting tramadol-induced delirium in two elderly patients. A case report. ( Dätwyler, S; Eschen, A; Künig, G; Schreiter Gasser, U, 2006)
"The effect of mirtazapine on steady-state plasma concentrations of the newer atypical antipsychotics clozapine, risperidone and olanzapine was investigated in 24 patients with chronic schizophrenia."7.72Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia. ( Canale, A; Crucitti, D; D'Arrigo, C; Malara, G; Muscatello, MR; Spina, E; Torre, DL; Zoccali, R, 2003)
"The efficacy of mianserin as a supplement in treating chronic schizophrenia was tested in 20 inpatients with schizophrenia who were receiving fixed doses of neuroleptics."7.68Effects of mianserin on negative symptoms in schizophrenia. ( Imai, T; Kai, S; Kajimura, N; Kaneyuki, H; Mizuki, Y; Suetsugi, M; Yamada, M, 1990)
"Tritiated imipramine binding to whole platelets was measured in 16 chronic pain patients who were free from major depression, and in a control group."7.67Modifications of [3H]imipramine binding sites in platelets of chronic pain patients treated with mianserin. ( Ambrosio, F; Andreoli, F; Arduino, C; Arsie, D; Ceccherelli, F; Dodi, G; Eandi, M; Magni, G, 1987)
"Mirtazapine is a relatively new so-called noradrenergic and specific serotonergic antidepressant, which is more specific and therefore generally better tolerated."6.71Mirtazapine is effective in the prophylactic treatment of chronic tension-type headache. ( Bendtsen, L; Jensen, R, 2004)
"Mood depression was evaluated at 0, 4 and 8 weeks by using Zung's Self-Rating Depression Scale and Hamilton Rating Scale for Depression."6.67Chronic tension-type headache, mood depression and serotonin: therapeutic effects of fluvoxamine and mianserine. ( Bolino, F; Di Cicco, L; Manna, V, 1994)
"1."5.29Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. ( Inanaga, K; Kuniyoshi, M; Miura, C; Nakamura, J, 1994)
" Mirtazapine has a prophylactic and ibuprofen an acute effect in tension-type headache."5.12Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache. ( Ashina, S; Bendtsen, L; Buchgreitz, L; Jensen, R, 2007)
" In a double-blind placebo-controlled study we examined the effect of add-on mianserin (15 mg/day), an agent with marked 5-HT2A antagonism, on cognitive functioning in 30 chronic hospitalized DSM-IV schizophrenia patients stabilized on typical antipsychotics."5.10Effect of the 5-HT2 antagonist mianserin on cognitive dysfunction in chronic schizophrenia patients: an add-on, double-blind placebo-controlled study. ( Fuchs, C; Gonopolsky, I; Koren, D; Poyurovsky, M; Schneidman, M; Weizman, A; Weizman, R, 2003)
"The reduction of pain by two antidepressants, clomipramine and mianserin, was, in this study on 253 patients with chronic idiopathic pain syndrome, found to be not better than a placebo when all patients were compared independently of the classification of pain."5.06Clomipramine and mianserin in chronic idiopathic pain syndrome. A placebo controlled study. ( Bech, P; Hansen, HJ; Langemark, M; Loldrup, D; Olesen, J, 1989)
"The effects of acute, systemic administration of amitriptyline, duloxetine and mirtazapine (antidepressant drugs that variously affect extracellular noradrenaline and serotonin levels) and the selective serotonin reuptake inhibitor (SSRI) citalopram were compared in rat models of experimental pain."3.73Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain. ( Blackburn-Munro, G; Bomholt, SF; Mikkelsen, JD, 2005)
"To evaluate the safety, tolerability and efficacy of mirtazapine in patients with the primary diagnosis of chronic pain and concomitant depression in an open post-marketing surveillance study."3.73The effect of mirtazapine in patients with chronic pain and concomitant depression. ( Freynhagen, R; Lipfert, P; Muth-Selbach, U; Stevens, MF; Tölle, TR; von Giesen, HJ; Zacharowski, K, 2006)
"We present the cases of two elderly patients with intermittent long-term tramadol intake against chronic back pain."3.73Unrecognised long-lasting tramadol-induced delirium in two elderly patients. A case report. ( Dätwyler, S; Eschen, A; Künig, G; Schreiter Gasser, U, 2006)
"The effect of mirtazapine on steady-state plasma concentrations of the newer atypical antipsychotics clozapine, risperidone and olanzapine was investigated in 24 patients with chronic schizophrenia."3.72Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia. ( Canale, A; Crucitti, D; D'Arrigo, C; Malara, G; Muscatello, MR; Spina, E; Torre, DL; Zoccali, R, 2003)
"The efficacy of mianserin as a supplement in treating chronic schizophrenia was tested in 20 inpatients with schizophrenia who were receiving fixed doses of neuroleptics."3.68Effects of mianserin on negative symptoms in schizophrenia. ( Imai, T; Kai, S; Kajimura, N; Kaneyuki, H; Mizuki, Y; Suetsugi, M; Yamada, M, 1990)
"Tritiated imipramine binding to whole platelets was measured in 16 chronic pain patients who were free from major depression, and in a control group."3.67Modifications of [3H]imipramine binding sites in platelets of chronic pain patients treated with mianserin. ( Ambrosio, F; Andreoli, F; Arduino, C; Arsie, D; Ceccherelli, F; Dodi, G; Eandi, M; Magni, G, 1987)
"The co-occurrence of substance use disorder (SUD) and major depressive disorder (MDD) is common and is often thought to impair response to antidepressant therapy."2.77Effect of concurrent substance use disorder on the effectiveness of single and combination antidepressant medications for the treatment of major depression: an exploratory analysis of a single-blind randomized trial. ( Balasubramani, GK; Davis, LL; Fava, M; Gaynes, BN; Howland, RH; Pilkinton, P; Rush, AJ; Trivedi, MH; Wisniewski, SR; Zisook, S, 2012)
"Mirtazapine adjunction was well tolerated and induced a significant improvement in cognitive performance, as measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS; Randolph, 1998) total score and by the subscales for immediate and delayed memory (p<."2.73Add-on mirtazapine enhances effects on cognition in schizophrenic patients under stabilized treatment with clozapine. ( Biondi, M; Delle Chiaie, R; Fiorentini, S; Salviati, M, 2007)
"Mirtazapine is a relatively new so-called noradrenergic and specific serotonergic antidepressant, which is more specific and therefore generally better tolerated."2.71Mirtazapine is effective in the prophylactic treatment of chronic tension-type headache. ( Bendtsen, L; Jensen, R, 2004)
"Mood depression was evaluated at 0, 4 and 8 weeks by using Zung's Self-Rating Depression Scale and Hamilton Rating Scale for Depression."2.67Chronic tension-type headache, mood depression and serotonin: therapeutic effects of fluvoxamine and mianserine. ( Bolino, F; Di Cicco, L; Manna, V, 1994)
"Steroids were restarted and his ataxia stabilized."1.46JC virus granule cell neuronopathy in the setting of chronic lymphopenia treated with recombinant interleukin-7. ( Angeles, MR; Bucelli, RC; Clifford, DB; Dang, X; Koralnik, IJ; Kuhlmann, FM; Major, EO; Ryschkewitsch, CF; Schmidt, RE; Schwetye, KE; Soleimani-Meigooni, DN, 2017)
"Treatment with mianserin resulted in a significant lowering of TNFα and IL-6 levels both in LPS-treated and LPS-untreated animals."1.40The influence of mianserin on TNF-α, IL-6 and IL-10 serum levels in rats under chronic mild stress. ( Bobkiewicz-Kozłowska, T; Manikowska, K; Mikołajczak, PŁ; Mikołajczyk, M, 2014)
"1."1.29Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. ( Inanaga, K; Kuniyoshi, M; Miura, C; Nakamura, J, 1994)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.98)18.7374
1990's10 (23.26)18.2507
2000's22 (51.16)29.6817
2010's8 (18.60)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, HG1
Grossman, SK1
Valdes-Rodriguez, R1
Berenato, F1
Korbutov, J1
Chan, YH1
Lavery, MJ1
Yosipovitch, G2
Bernhard, JD1
Warden, D2
Trivedi, MH4
Carmody, T1
Toups, M1
Zisook, S2
Lesser, I1
Myers, A1
Kurian, KR1
Morris, D1
Rush, AJ3
Manikowska, K1
Mikołajczyk, M1
Mikołajczak, PŁ1
Bobkiewicz-Kozłowska, T1
Smith, JH1
Soleimani-Meigooni, DN1
Schwetye, KE1
Angeles, MR1
Ryschkewitsch, CF1
Major, EO1
Dang, X1
Koralnik, IJ1
Schmidt, RE1
Clifford, DB1
Kuhlmann, FM1
Bucelli, RC1
Khan, AY1
Golewale, MH1
Kahn, DA1
Klein, DN1
Arnow, BA1
Barkin, JL1
Dowling, F1
Kocsis, JH1
Leon, AC1
Manber, R1
Rothbaum, BO1
Wisniewski, SR3
Davis, LL1
Pilkinton, P1
Gaynes, BN1
Howland, RH1
Balasubramani, GK1
Fava, M2
Sung, SC1
Haley, CL1
Nierenberg, AA3
Morris, DW1
Kurian, BT1
Poyurovsky, M1
Koren, D1
Gonopolsky, I1
Schneidman, M1
Fuchs, C1
Weizman, A2
Weizman, R1
Zoccali, R1
Muscatello, MR1
Torre, DL1
Malara, G1
Canale, A1
Crucitti, D1
D'Arrigo, C1
Spina, E1
Quitkin, FM1
Kremer, C1
Keller, MB3
Thase, ME2
Bendtsen, L2
Jensen, R2
Bomholt, SF1
Mikkelsen, JD1
Blackburn-Munro, G1
Thormann, H1
Bindslev-Jensen, C1
Bigatà, X1
Sais, G1
Soler, F1
Freynhagen, R1
Muth-Selbach, U1
Lipfert, P1
Stevens, MF1
Zacharowski, K1
Tölle, TR1
von Giesen, HJ1
Gerrits, M1
Bakker, PL1
Koch, T1
Ter Horst, GJ1
Künig, G1
Dätwyler, S1
Eschen, A1
Schreiter Gasser, U1
Tajti, J1
Almási, J1
Buchgreitz, L1
Ashina, S1
Nagata, T1
Ono, K1
Nakayama, K1
Silver, N1
Delle Chiaie, R1
Salviati, M1
Fiorentini, S1
Biondi, M1
Kuniyoshi, M1
Nakamura, J1
Miura, C1
Inanaga, K1
Manna, V1
Bolino, F1
Di Cicco, L1
Onghena, P2
De Cuyper, H2
Van Houdenhove, B2
Verstraeten, D2
Hoes, MJ1
Zeijpveld, JH1
Brannon, GE1
Stone, KD1
Riabus, MV1
Kolosova, OA1
Grinshpoon, A1
Valevski, A1
Moskowitz, M1
Panagides, J1
Spierings, EL1
McHarg, AM1
McHarg, JF1
Nakamura, S1
Mizuki, Y1
Kajimura, N1
Imai, T1
Suetsugi, M1
Kai, S1
Kaneyuki, H1
Yamada, M1
Loldrup, D1
Langemark, M1
Hansen, HJ1
Olesen, J1
Bech, P1
Magni, G1
Andreoli, F1
Arduino, C1
Arsie, D1
Ceccherelli, F1
Ambrosio, F1
Dodi, G1
Eandi, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Combining Medications to Enhance Depression Outcomes[NCT00590863]Phase 4665 participants (Actual)Interventional2008-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Quality of Life Inventory

The Quality of Life Inventory (QOLI) is a 32-item comprehensive self-report of satisfaction in 16 areas of life, such as love, work, and health. Each area is rated in terms of satisfaction and the relationship of that area to overall quality of life. It yields an overall raw score and satisfaction ratings for the 16 individual areas of life. The QOLI raw score is an average of weighted satisfaction ratings computed only over areas of life judged to be Important or Extremely Important to the respondent. Higher scores indicate higher reported quality of life. (NCT00590863)
Timeframe: Measured at Month 7

Interventionunits on a scale (Mean)
Escitalopram + Bupropion SR0.6
Venlafaxine XR + Mirtazapine0.4
Escitalopram + Placebo0.4

Quick Inventory of Depressive Symptoms

Percentage of patients that achieve remission, as defined as QIDS total score below 6 for last 2 study visits. QIDS depression scores range from 0 (normal) to 27 (very severe). (NCT00590863)
Timeframe: Measured at Month 7

Interventionpercentage of participants (Number)
Escitalopram + Bupropion SR46.6
Venlafaxine XR + Mirtazapine41.8
Escitalopram + Placebo46.0

Reviews

5 reviews available for mianserin and Chronic Illness

ArticleYear
Clinical practice. Chronic pruritus.
    The New England journal of medicine, 2013, Apr-25, Volume: 368, Issue:17

    Topics: Amines; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cyclohexanecarboxylic A

2013
[Effects of mirtazapine in patients with chronic tension-type headache. Literature review].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2006, Volume: 8, Issue:2

    Topics: Age Factors; Analgesics; Chronic Disease; Female; Humans; Male; Mianserin; Mirtazapine; Prevalence;

2006
Headache (chronic tension-type).
    American family physician, 2007, Jul-01, Volume: 76, Issue:1

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents; Biofeedback, Psychology; Chronic Dis

2007
The long-term treatment of depression.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Chronic Disease; Combined Modality Therapy;

1999
Axonal sprouting of noradrenergic locus coeruleus neurons following repeated stress and antidepressant treatment.
    Progress in brain research, 1991, Volume: 88

    Topics: Animals; Antidepressive Agents; Axons; Chronic Disease; Desipramine; Electroconvulsive Therapy; Elec

1991

Trials

13 trials available for mianserin and Chronic Illness

ArticleYear
Adherence to antidepressant combinations and monotherapy for major depressive disorder: a CO-MED report of measurement-based care.
    Journal of psychiatric practice, 2014, Volume: 20, Issue:2

    Topics: Adult; Antidepressive Agents; Bupropion; Chronic Disease; Citalopram; Cyclohexanols; Depressive Diso

2014
Effect of concurrent substance use disorder on the effectiveness of single and combination antidepressant medications for the treatment of major depression: an exploratory analysis of a single-blind randomized trial.
    Depression and anxiety, 2012, Volume: 29, Issue:2

    Topics: Adolescent; Antidepressive Agents; Bupropion; Chronic Disease; Citalopram; Cyclohexanols; Depressive

2012
The impact of chronic depression on acute and long-term outcomes in a randomized trial comparing selective serotonin reuptake inhibitor monotherapy versus each of 2 different antidepressant medication combinations.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:7

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Bupropion; Chronic Disease; Citalopram; Comorbidity;

2012
Effect of the 5-HT2 antagonist mianserin on cognitive dysfunction in chronic schizophrenia patients: an add-on, double-blind placebo-controlled study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2003, Volume: 13, Issue:2

    Topics: Adult; Analysis of Variance; Chi-Square Distribution; Chronic Disease; Cognition Disorders; Double-B

2003
Placebo-controlled continuation treatment with mirtazapine: acute pattern of response predicts relapse.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:5

    Topics: Adult; Aged; Antidepressive Agents; Chronic Disease; Depressive Disorder; Female; Humans; Long-Term

2004
Mirtazapine is effective in the prophylactic treatment of chronic tension-type headache.
    Neurology, 2004, May-25, Volume: 62, Issue:10

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Area Under Curve; Chro

2004
Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache.
    European journal of neurology, 2007, Volume: 14, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dose-

2007
Add-on mirtazapine enhances effects on cognition in schizophrenic patients under stabilized treatment with clozapine.
    Experimental and clinical psychopharmacology, 2007, Volume: 15, Issue:6

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antipsychotic Agents; Brief Psychiatric R

2007
Chronic tension-type headache, mood depression and serotonin: therapeutic effects of fluvoxamine and mianserine.
    Headache, 1994, Volume: 34, Issue:1

    Topics: Adult; Chronic Disease; Depression; Double-Blind Method; Female; Fluvoxamine; Headache; Humans; Male

1994
Mianserin and chronic pain: a double-blind placebo-controlled process and outcome study.
    Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:3

    Topics: Adult; Chronic Disease; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Mianserin; M

1993
Efficacy of mirtazapine for prevention of depressive relapse: a placebo-controlled double-blind trial of recently remitted high-risk patients.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:10

    Topics: Adult; Chronic Disease; Depressive Disorder, Major; Double-Blind Method; Female; Follow-Up Studies;

2001
Chronic idiopathic pain, mianserin and 'masked' depression.
    Psychotherapy and psychosomatics, 1992, Volume: 58, Issue:1

    Topics: Adult; Chronic Disease; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Mianserin; M

1992
Clomipramine and mianserin in chronic idiopathic pain syndrome. A placebo controlled study.
    Psychopharmacology, 1989, Volume: 99, Issue:1

    Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Clomipramine; Female; Humans; Ma

1989

Other Studies

25 other studies available for mianserin and Chronic Illness

ArticleYear
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4

    Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy,

2017
The influence of mianserin on TNF-α, IL-6 and IL-10 serum levels in rats under chronic mild stress.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:1

    Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Interleukin-10; Interleukin-6; L

2014
Mirtazapine for new daily persistent headache-associated chronic nausea.
    Headache, 2015, Volume: 55, Issue:1

    Topics: Chronic Disease; Female; Headache; Histamine H1 Antagonists; Humans; Mianserin; Middle Aged; Mirtaza

2015
JC virus granule cell neuronopathy in the setting of chronic lymphopenia treated with recombinant interleukin-7.
    Journal of neurovirology, 2017, Volume: 23, Issue:1

    Topics: Aged; Ataxia; Chronic Disease; Hamartoma Syndrome, Multiple; Humans; Immunocompromised Host; Immunog

2017
A case of chronic drug-induced neutropenia.
    Journal of psychiatric practice, 2008, Volume: 14, Issue:4

    Topics: Anti-Anxiety Agents; Anti-Infective Agents; Anxiety Disorders; Chronic Disease; Female; Humans; Metr

2008
Early adversity in chronic depression: clinical correlates and response to pharmacotherapy.
    Depression and anxiety, 2009, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Age of Onset; Aged; Algorithms; Antidepressive Agents; Anxiety Disorders; Bupropi

2009
Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia.
    Pharmacological research, 2003, Volume: 48, Issue:4

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clinical Trials

2003
[Unclear chronic aches. Often depression plays a part therein].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Age

2003
Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain.
    Neuropharmacology, 2005, Volume: 48, Issue:2

    Topics: Acute Disease; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Chronic Disease; Citalopra

2005
Mirtazapine for chronic urticaria.
    Acta dermato-venereologica, 2004, Volume: 84, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Carbon Radioisotopes; Chronic Disease; Female; Humans; Male; Mi

2004
Severe chronic urticaria: response to mirtazapine.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Chronic Disease; Female; Humans; Mianserin; Mirtazapine; Remissi

2005
The effect of mirtazapine in patients with chronic pain and concomitant depression.
    Current medical research and opinion, 2006, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Chronic Disease; Depre

2006
Stress-induced sensitization of the limbic system in ovariectomized rats is partly restored by cyclic 17beta-estradiol administration.
    The European journal of neuroscience, 2006, Volume: 23, Issue:7

    Topics: Amygdala; Animals; Antidepressive Agents; Chronic Disease; Dentate Gyrus; Drug Interactions; Estradi

2006
Unrecognised long-lasting tramadol-induced delirium in two elderly patients. A case report.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Delirium; Drug I

2006
Anorexia nervosa with chronic episodes for more than 30 years in a patient with a comorbid schizotypal personality disorder.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:4

    Topics: Anorexia Nervosa; Antidepressive Agents, Second-Generation; Benzodiazepines; Body Weight; Bulimia; C

2007
Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:2

    Topics: Adult; Biogenic Monoamines; Chronic Disease; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic

1994
Mirtazapine as treatment for serotonin syndrome.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:2

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Female; Humans;

1996
The use of mirtazapine in a patient with chronic pain.
    Journal of pain and symptom management, 1999, Volume: 18, Issue:5

    Topics: Accidental Falls; Antidepressive Agents, Tricyclic; Back Pain; Chronic Disease; Humans; Male; Mianse

1999
[Treatment of various forms of tense headaches by biofeedback].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1999, Volume: 99, Issue:12

    Topics: Adult; Biofeedback, Psychology; Chronic Disease; Combined Modality Therapy; Electromyography; Female

1999
Beneficial effect of the addition of the 5-HT 2A/2C and alpha2 antagonist mianserin to ongoing haloperidol treatment in drug-resistant chronically hospitalized schizophrenic patients.
    European psychiatry : the journal of the Association of European Psychiatrists, 2000, Volume: 15, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Brief Psychia

2000
[Depressive disorders. A third have a chronic course].
    MMW Fortschritte der Medizin, 2001, May-28, Volume: 143 Suppl 2

    Topics: Antidepressive Agents, Tricyclic; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Dr

2001
Acute and chronic hypertensive headache and hypertensive encephalopathy.
    Cephalalgia : an international journal of headache, 2002, Volume: 22, Issue:4

    Topics: Acute Disease; Antidepressive Agents; Antihypertensive Agents; Anxiety; Arterioles; Cerebral Arterie

2002
Leucopenia in association with mianserin treatment.
    British medical journal, 1979, Mar-03, Volume: 1, Issue:6163

    Topics: Aged; Chronic Disease; Depression; Dibenzazepines; Female; Humans; Leukopenia; Mianserin

1979
Effects of mianserin on negative symptoms in schizophrenia.
    International clinical psychopharmacology, 1990, Volume: 5, Issue:2

    Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Brain; Chronic Disease; Drug Therapy, Combination

1990
Modifications of [3H]imipramine binding sites in platelets of chronic pain patients treated with mianserin.
    Pain, 1987, Volume: 30, Issue:3

    Topics: Binding Sites; Blood Platelets; Chronic Disease; Depressive Disorder; Female; Humans; Imipramine; Ma

1987