mianserin has been researched along with Arrhythmia in 5 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of mianserin, a tetracyclic antidepressant, and adinazolam, a new triazolobenzodiazepine which has antidepressant activity, on intraventricular conduction and the incidence of arrhythmias induced by programmed ventricular stimulation were studied in the dog heart after myocardial infarction and compared to the effects of amitriptyline, a standard tricyclic antidepressant." | 3.68 | Effects of antidepressants on the intraventricular conduction and the incidence of arrhythmias induced by programmed ventricular stimulation in the dog heart after myocardial infarction. ( Hashimoto, H; Nagashima, S; Nakashima, M; Nishimoto, M; Ozaki, T, 1990) |
| "The presence or absence of cardiac arrhythmias was recorded." | 2.65 | Mianserin, maprotiline and intracardiac conduction. ( Edwards, JG; Goldie, A, 1983) |
| "Amineptine, however, was ineffective in preventing reperfusion arrhythmias even in a high concentration, this agent did not decrease heart rate." | 1.27 | Comparison of the effect of antidepressant drugs on arrhythmias in the isolated rat heart subjected to myocardial ischaemia and reperfusion. ( Bril, A; Rochette, L, 1987) |
| " It is concluded that all four drugs show the toxic effects classically associated with tricyclic antidepressants but the relative toxicity amongst these agents varies considerably and is in the order amitriptyline greater than imipramine greater than maprotiline greater than mianserin." | 1.26 | The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo. ( Hughes, IE; Radwan, S, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, JG | 1 |
| Goldie, A | 1 |
| Hughes, IE | 2 |
| Radwan, S | 1 |
| Harper, B | 1 |
| Nishimoto, M | 1 |
| Hashimoto, H | 1 |
| Ozaki, T | 1 |
| Nagashima, S | 1 |
| Nakashima, M | 1 |
| Bril, A | 1 |
| Rochette, L | 1 |
1 trial available for mianserin and Arrhythmia
| Article | Year |
|---|---|
Mianserin, maprotiline and intracardiac conduction.
Topics: Adolescent; Adult; Anthracenes; Arrhythmias, Cardiac; Depressive Disorder; Dibenzazepines; Double-Bl | 1983 |
4 other studies available for mianserin and Arrhythmia
| Article | Year |
|---|---|
The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo.
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Behavior | 1979 |
A comparison in rabbit isolated hearts of the dysrhythmogenic potential of amitriptyline, maprotiline and mianserin in relation to their ability to block noradrenaline uptake.
Topics: Amitriptyline; Animals; Anthracenes; Arrhythmias, Cardiac; Dibenzazepines; Drug Interactions; Female | 1977 |
Effects of antidepressants on the intraventricular conduction and the incidence of arrhythmias induced by programmed ventricular stimulation in the dog heart after myocardial infarction.
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents; Arrhythmias, Cardiac; Benzodiaze | 1990 |
Comparison of the effect of antidepressant drugs on arrhythmias in the isolated rat heart subjected to myocardial ischaemia and reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Antidepressive Agents; Arrhythmias, Cardiac; Coronary Disease; Dibe | 1987 |