mianserin has been researched along with Apoplexy in 4 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with ischemic stroke received either 30 mg mirtazapine or no antidepressant medication from day 1 after the stroke in an open, randomized study design." | 9.11 | Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke. ( Bohrer, E; Heuser, I; Niedermaier, N; Schlattmann, P; Schulte, K, 2004) |
| "We assessed the prevalence and associations of symptoms of insomnia in patients with acute ischemic stroke, and evaluated whether mianserin as a sedative antidepressant is beneficial in the treatment of poststroke insomnia." | 9.10 | Complaints of poststroke insomnia and its treatment with mianserin. ( Berg, A; Kaste, M; Lehtihalmes, M; Lönnqvist, J; Lönnqvist, R; Meririnne, E; Palomäki, H, 2003) |
| "Mirtazapine may be a probably effective treatment in stroke survivors with obstructive sleep apnea who refuse nasal CPAP treatment." | 6.73 | Success and failure of mirtazapine as alternative treatment in elderly stroke patients with sleep apnea-a preliminary open trial. ( Brunner, H, 2008) |
| "Patients with ischemic stroke received either 30 mg mirtazapine or no antidepressant medication from day 1 after the stroke in an open, randomized study design." | 5.11 | Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke. ( Bohrer, E; Heuser, I; Niedermaier, N; Schlattmann, P; Schulte, K, 2004) |
| "We assessed the prevalence and associations of symptoms of insomnia in patients with acute ischemic stroke, and evaluated whether mianserin as a sedative antidepressant is beneficial in the treatment of poststroke insomnia." | 5.10 | Complaints of poststroke insomnia and its treatment with mianserin. ( Berg, A; Kaste, M; Lehtihalmes, M; Lönnqvist, J; Lönnqvist, R; Meririnne, E; Palomäki, H, 2003) |
| "Mirtazapine may be a probably effective treatment in stroke survivors with obstructive sleep apnea who refuse nasal CPAP treatment." | 2.73 | Success and failure of mirtazapine as alternative treatment in elderly stroke patients with sleep apnea-a preliminary open trial. ( Brunner, H, 2008) |
| "Depression is associated with stroke severity and functional impairment, and with the male sex at 18 months." | 2.71 | Poststroke depression: an 18-month follow-up. ( Berg, A; Kaste, M; Lehtihalmes, M; Lönnqvist, J; Palomäki, H, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palomäki, H | 2 |
| Berg, A | 2 |
| Meririnne, E | 1 |
| Kaste, M | 2 |
| Lönnqvist, R | 1 |
| Lehtihalmes, M | 2 |
| Lönnqvist, J | 2 |
| Niedermaier, N | 1 |
| Bohrer, E | 1 |
| Schulte, K | 1 |
| Schlattmann, P | 1 |
| Heuser, I | 1 |
| Brunner, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Agomelatine in the Prevention of Poststroke Depression[NCT05426304] | Phase 4 | 420 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for mianserin and Apoplexy
| Article | Year |
|---|---|
Complaints of poststroke insomnia and its treatment with mianserin.
Topics: Age Factors; Aged; Antidepressive Agents, Second-Generation; Depression; Dose-Response Relationship, | 2003 |
Poststroke depression: an 18-month follow-up.
Topics: Antidepressive Agents, Second-Generation; Depression; Female; Follow-Up Studies; Humans; Male; Mians | 2003 |
Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke.
Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Administration Schedule; Female; F | 2004 |
Success and failure of mirtazapine as alternative treatment in elderly stroke patients with sleep apnea-a preliminary open trial.
Topics: Adrenergic alpha-Antagonists; Aged; Body Mass Index; Continuous Positive Airway Pressure; Electromyo | 2008 |