mianserin has been researched along with Apnea, Obstructive Sleep in 5 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mirtazapine is an a2A antagonist and mixed 5-HT2/5-HT3 antagonist that has been proposed as a potential treatment for obstructive sleep apnea (OSA)." | 2.73 | Two randomized placebo-controlled trials to evaluate the efficacy and tolerability of mirtazapine for the treatment of obstructive sleep apnea. ( Buchanan, PR; Crompton, R; Desai, AV; Gendreau, RM; Grunstein, RR; Kranzler, J; Marshall, NS; Melehan, KL; Rao, SG; Wong, KK; Yee, BJ; Zack, N, 2008) |
| "In an animal model of central apnea the use of mirtazapine produced a significant reduction of apneas." | 1.32 | Effectiveness of mirtazapine in the treatment of sleep apnea/hypopnea syndrome (SAHS). ( Castillo, JL; Guilleminault, C; Menendez, P; Segovia, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marshall, NS | 1 |
| Yee, BJ | 1 |
| Desai, AV | 1 |
| Buchanan, PR | 1 |
| Wong, KK | 1 |
| Crompton, R | 1 |
| Melehan, KL | 1 |
| Zack, N | 2 |
| Rao, SG | 1 |
| Gendreau, RM | 1 |
| Kranzler, J | 2 |
| Grunstein, RR | 1 |
| Levendowski, DJ | 1 |
| Rao, S | 1 |
| Wong, K | 1 |
| Gendreau, M | 1 |
| Zavora, T | 1 |
| Westbrook, PR | 1 |
| Kohler, M | 1 |
| Bloch, KE | 1 |
| Stradling, JR | 1 |
| Castillo, JL | 1 |
| Menendez, P | 1 |
| Segovia, L | 1 |
| Guilleminault, C | 1 |
| Carley, DW | 1 |
| Olopade, C | 1 |
| Ruigt, GS | 1 |
| Radulovacki, M | 1 |
1 review available for mianserin and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Pharmacological approaches to the treatment of obstructive sleep apnoea.
Topics: Animals; Cholinesterase Inhibitors; Humans; Mianserin; Mirtazapine; Protriptyline; Pulmonary Ventila | 2009 |
3 trials available for mianserin and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Two randomized placebo-controlled trials to evaluate the efficacy and tolerability of mirtazapine for the treatment of obstructive sleep apnea.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Drug Tolerance; Female; Histamine H1 Antagonists; Hu | 2008 |
Assessment of the test-retest reliability of laboratory polysomnography.
Topics: Adrenergic alpha-Antagonists; Adult; Body Mass Index; Continuous Positive Airway Pressure; Female; H | 2009 |
Efficacy of mirtazapine in obstructive sleep apnea syndrome.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cross-Over Studies; Dose-Response Relationship, Drug; | 2007 |
1 other study available for mianserin and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Effectiveness of mirtazapine in the treatment of sleep apnea/hypopnea syndrome (SAHS).
Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Continuous Positive Airway Pressure; Disorders | 2004 |