mianserin has been researched along with Anxiety in 34 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomized, placebo-controlled trial, mirtazapine significantly improved early satiation, quality of life, gastrointestinal-specific anxiety, nutrient tolerance, and weight loss in patients with FD." | 9.22 | Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss. ( Arts, J; Boeckxstaens, G; Caenepeel, P; Carbone, F; Holvoet, L; Ly, HG; Tack, J; Van Oudenhove, L; Vanheel, H; Vanuytsel, T, 2016) |
| "The VAS anxiety scale was lower in group M + D after mirtazapine administration." | 9.13 | Premedication with mirtazapine reduces preoperative anxiety and postoperative nausea and vomiting. ( Chen, CC; Hsu, YW; Hung, YC; Ko, YP; Lao, HC; Lin, CS, 2008) |
| " In a third trial, mianserin was found to be as effective as diazepam in the treatment of anxiety states in general practice." | 9.04 | Mianserin in the treatment of depressive illness and anxiety states in general practice. ( Murphy, JE, 1978) |
| "Forty psychiatric out-patients with primary anxiety entered a double-blind trial comparing 2 weeks of treatment with mianserin 30--60 mg daily or diazepam 15--30 mg daily, followed by 2 weeks of single-blind placebo administration." | 9.04 | A controlled comparative trial of mianserin and diazepam in the treatment of anxiety states in psychiatric out-patients. ( Conti, L; Pinder, RM, 1979) |
| " There were more withdrawals and dosage changes with nomifensine than with mianserin." | 6.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
| " In addition, a dose-response effect was seen with Org 3770, 15 mg seeming optimal." | 6.66 | A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery. ( Bettum, V; Dunbar, GC; Jørgensen, J; Steffensen, K; Sørensen, M; Viby-Mogensen, J, 1985) |
| "In a randomized, placebo-controlled trial, mirtazapine significantly improved early satiation, quality of life, gastrointestinal-specific anxiety, nutrient tolerance, and weight loss in patients with FD." | 5.22 | Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss. ( Arts, J; Boeckxstaens, G; Caenepeel, P; Carbone, F; Holvoet, L; Ly, HG; Tack, J; Van Oudenhove, L; Vanheel, H; Vanuytsel, T, 2016) |
| "The VAS anxiety scale was lower in group M + D after mirtazapine administration." | 5.13 | Premedication with mirtazapine reduces preoperative anxiety and postoperative nausea and vomiting. ( Chen, CC; Hsu, YW; Hung, YC; Ko, YP; Lao, HC; Lin, CS, 2008) |
| " In a third trial, mianserin was found to be as effective as diazepam in the treatment of anxiety states in general practice." | 5.04 | Mianserin in the treatment of depressive illness and anxiety states in general practice. ( Murphy, JE, 1978) |
| " In the present study, female rats were treated long term with clinically used antidepressants (fluoxetine, nortriptyline or mirtazapine) and subjected to the plus-maze discriminative avoidance task to evaluate learning, memory, extinction and anxiety-related behaviors as well as behavioral despair in the forced swimming test." | 3.78 | Antidepressants differentially modify the extinction of an aversive memory task in female rats. ( Cabral, A; Ferreira, LS; Izídio, GS; Macedo, PT; Melo, TG; Ribeiro, AM; Silva, RH; Sousa, DS, 2012) |
| " Single doses of 5-HT2 antagonists, mianserin (5mg/kg) and ritanserin (1mg/kg), effectively ameliorated withdrawal anxiety in the rat, returning behavioural function in the social interaction test and elevated plus maze to levels comparable to vehicle-treated animals." | 3.73 | Attenuation of benzodiazepine withdrawal anxiety in the rat by serotonin antagonists. ( Begg, DP; Hallam, KT; Norman, TR, 2005) |
| "Mianserin (or placebo) was added to the routine medication protocol, during the 3-week in-patient phase of detoxification in a prospective, randomized, double blind, placebo controlled study." | 2.71 | The effect of mianserin add-on, on the intensity of opioid withdrawal symptoms during detoxification program--a randomized, double blind, placebo controlled, prospective study. ( Bar-Hamburger, R; Herman, I; Pick, CG; Schreiber, S; Shamir, D, 2005) |
| "Mirtazapine safety was assessed by interview during each follow-up period on days 3 and 14 after treatment." | 2.71 | Mirtazapine in amphetamine detoxification: a placebo-controlled pilot study. ( Kongsakon, R; Papadopoulos, KI; Saguansiritham, R, 2005) |
| "Imipramine was more effective against the clusters related to core symptoms of depression: "depression and guilt", "retardation", and "melancholia", respectively." | 2.69 | Depressed in-patients respond differently to imipramine and mirtazapine. ( Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW, 1999) |
| " There were more withdrawals and dosage changes with nomifensine than with mianserin." | 2.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
| " In addition, a dose-response effect was seen with Org 3770, 15 mg seeming optimal." | 2.66 | A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery. ( Bettum, V; Dunbar, GC; Jørgensen, J; Steffensen, K; Sørensen, M; Viby-Mogensen, J, 1985) |
| "Buspirone has an indication for generalized anxiety disorder though studies show only a minimal benefit." | 2.53 | Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD. ( Bielefeldt, K; Szigethy, E; Thorkelson, G, 2016) |
| " The sexual symptoms resolved gradually after a few days and reappeared upon every dosage increase." | 1.35 | A case of mirtazapine-induced spontaneous orgasms in a female patient. ( Ben-Zion, I; Shalev, H; Shiber, A, 2009) |
| " Long-term administration with imipramine or mirtazapine (10 mg/kg, i." | 1.31 | Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats. ( Biggio, G; Dazzi, L; Ladu, S; Pira, L; Rivano, A; Spiga, F; Vacca, G, 2002) |
| "Diazepam was used as a positive control." | 1.30 | A comparative study of the effects of selective and non-selective 5-HT2 receptor subtype antagonists in rat and mouse models of anxiety. ( Griebel, G; Perrault, G; Sanger, DJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.65) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 12 (35.29) | 29.6817 |
| 2010's | 8 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanidir, C | 1 |
| Tanidir, IC | 1 |
| Tuzcu, V | 1 |
| An, Y | 1 |
| Inoue, T | 1 |
| Kitaichi, Y | 1 |
| Nakagawa, S | 1 |
| Wang, C | 1 |
| Chen, C | 1 |
| Song, N | 1 |
| Kusumi, I | 1 |
| Tack, J | 1 |
| Ly, HG | 1 |
| Carbone, F | 1 |
| Vanheel, H | 1 |
| Vanuytsel, T | 1 |
| Holvoet, L | 1 |
| Boeckxstaens, G | 1 |
| Caenepeel, P | 1 |
| Arts, J | 1 |
| Van Oudenhove, L | 1 |
| Arora, S | 1 |
| Vohora, D | 1 |
| Huang, WL | 1 |
| Liao, SC | 1 |
| Kuo, TB | 1 |
| Chang, LR | 1 |
| Chen, TT | 1 |
| Chen, IM | 1 |
| Yang, CC | 1 |
| Thorkelson, G | 1 |
| Bielefeldt, K | 1 |
| Szigethy, E | 1 |
| Melo, TG | 1 |
| Izídio, GS | 1 |
| Ferreira, LS | 1 |
| Sousa, DS | 1 |
| Macedo, PT | 1 |
| Cabral, A | 1 |
| Ribeiro, AM | 1 |
| Silva, RH | 1 |
| Udo, I | 1 |
| Gash, A | 1 |
| Kesim, M | 1 |
| Yaris, F | 1 |
| Kadioglu, M | 1 |
| Yaris, E | 1 |
| Kalyoncu, NI | 1 |
| Ulku, C | 1 |
| Liappas, J | 1 |
| Paparrigopoulos, T | 1 |
| Tzavellas, E | 1 |
| Rabavilas, A | 1 |
| Begg, DP | 1 |
| Hallam, KT | 1 |
| Norman, TR | 1 |
| Herman, I | 1 |
| Shamir, D | 1 |
| Bar-Hamburger, R | 1 |
| Pick, CG | 1 |
| Schreiber, S | 1 |
| Kongsakon, R | 1 |
| Papadopoulos, KI | 1 |
| Saguansiritham, R | 1 |
| Chen, CC | 1 |
| Lin, CS | 1 |
| Ko, YP | 1 |
| Hung, YC | 1 |
| Lao, HC | 1 |
| Hsu, YW | 1 |
| Shalev, H | 1 |
| Ben-Zion, I | 1 |
| Shiber, A | 1 |
| Shchukina, EP | 1 |
| Kinkul'kina, MA | 1 |
| Grove, A | 1 |
| Lipworth, BJ | 1 |
| Ingram, CG | 1 |
| Clark, RA | 1 |
| Dhillon, DP | 1 |
| Rocha, B | 1 |
| Rigo, M | 1 |
| Di Scala, G | 1 |
| Sandner, G | 1 |
| Hoyer, D | 1 |
| Lal, H | 2 |
| Prather, PL | 2 |
| Rezazadeh, SM | 2 |
| Griebel, G | 1 |
| Perrault, G | 1 |
| Sanger, DJ | 1 |
| Gerritsen, AW | 1 |
| Bruijn, JA | 1 |
| Moleman, P | 1 |
| Mulder, PG | 1 |
| van den Broek, WW | 1 |
| Davis, J | 1 |
| Barkin, RL | 1 |
| Dazzi, L | 2 |
| Spiga, F | 2 |
| Pira, L | 2 |
| Ladu, S | 2 |
| Vacca, G | 2 |
| Rivano, A | 2 |
| Jentsch, JD | 1 |
| Biggio, G | 2 |
| Belzung, C | 1 |
| Le Guisquet, AM | 1 |
| Barreau, S | 1 |
| Calatayud, F | 1 |
| Spierings, EL | 1 |
| Murphy, JE | 1 |
| Conti, L | 1 |
| Pinder, RM | 1 |
| Ulrich, G | 1 |
| Harms, K | 1 |
| Fleischhauer, J | 1 |
| Dunbar, GC | 2 |
| Naarala, M | 1 |
| Hiltunen, H | 1 |
| Granier, F | 1 |
| Girard, M | 1 |
| Schmitt, L | 1 |
| Boscredon, J | 1 |
| Oules, J | 1 |
| Escande, M | 1 |
| Sørensen, M | 1 |
| Jørgensen, J | 1 |
| Viby-Mogensen, J | 1 |
| Bettum, V | 1 |
| Steffensen, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 4 Study of Mirtazapine in Functional Dyspepsia Patients With Weight Loss[NCT01240096] | Phase 4 | 35 participants (Anticipated) | Interventional | 2006-09-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mianserin and Anxiety
| Article | Year |
|---|---|
Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD.
Topics: Adolescent; Adult; Affect; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Bupropion | 2016 |
13 trials available for mianserin and Anxiety
| Article | Year |
|---|---|
Efficacy of Mirtazapine in Patients With Functional Dyspepsia and Weight Loss.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Anxiety; Double-Blind Method; Dyspepsia; Female; Humans; | 2016 |
Mirtazapine and venlafaxine in the management of collateral psychopathology during alcohol detoxification.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Central Nervous System Depressants; | 2005 |
The effect of mianserin add-on, on the intensity of opioid withdrawal symptoms during detoxification program--a randomized, double blind, placebo controlled, prospective study.
Topics: Analysis of Variance; Antidepressive Agents, Second-Generation; Anxiety; Depressive Disorder; Double | 2005 |
Mirtazapine in amphetamine detoxification: a placebo-controlled pilot study.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Antidepressive Agents, Tricyclic; Anxiety; Arousal | 2005 |
Premedication with mirtazapine reduces preoperative anxiety and postoperative nausea and vomiting.
Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antiemetics; Anxiety; Double-Blind Method; Female; G | 2008 |
A comparison of the effects of prednisolone and mianserin on ventilatory, exercise and psychometric parameters in patients with chronic obstructive pulmonary disease.
Topics: Aged; Anxiety; Double-Blind Method; Exercise; Female; Heart Rate; Humans; Lung Diseases, Obstructive | 1995 |
Depressed in-patients respond differently to imipramine and mirtazapine.
Topics: Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Anxiety | 1999 |
Mianserin in the treatment of depressive illness and anxiety states in general practice.
Topics: Adolescent; Adult; Anxiety; Clinical Trials as Topic; Depression; Diazepam; Dibenzazepines; Double-B | 1978 |
A controlled comparative trial of mianserin and diazepam in the treatment of anxiety states in psychiatric out-patients.
Topics: Adolescent; Adult; Ambulatory Care; Anxiety; Clinical Trials as Topic; Diazepam; Dibenzazepines; Dou | 1979 |
[Studies with a behavior-oriented evaluation scale for depressive inhibition and agitation. Results of a video-documented amitriptyline-mianserine study].
Topics: Amitriptyline; Anxiety; Depression; Female; Humans; Inhibition, Psychological; Mianserin; Psychologi | 1976 |
A double-blind group comparison of mianserin and clomipramine in the treatment of mildly depressed psychiatric out-patients.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Clomipramine; Depression; Dibenzazepines; Female; Humans; Male; | 1985 |
Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Bipolar Disorder; Depre | 1985 |
A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery.
Topics: Adult; Anxiety; Blood Pressure; Diazepam; Dibenzazepines; Dose-Response Relationship, Drug; Double-B | 1985 |
20 other studies available for mianserin and Anxiety
| Article | Year |
|---|---|
Treatment of depression in an adolescent with cardiomyopathy and arrhythmia.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Anxiety; Cardiomyopathy, Hypertrophic; Depression; Ele | 2015 |
Subchronic lithium treatment increases the anxiolytic-like effect of mirtazapine on the expression of contextual conditioned fear.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Conditioning, Psychological; Dose-Response | 2015 |
Comparative Evaluation of Partial α2 -Adrenoceptor Agonist and Pure α2 -Adrenoceptor Antagonist on the Behavioural Symptoms of Withdrawal after Chronic Alcohol Administration in Mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Alcoholism; Animals; Anxiety; Be | 2016 |
The Effects of Antidepressants and Quetiapine on Heart Rate Variability.
Topics: Adult; Aged; Antidepressive Agents; Anxiety; Depression; Female; Heart Rate; Humans; Linear Models; | 2016 |
Antidepressants differentially modify the extinction of an aversive memory task in female rats.
Topics: Animals; Antidepressive Agents; Anxiety; Avoidance Learning; Extinction, Psychological; Female; Fluo | 2012 |
Challenges in management of complex panic disorder in a palliative care setting.
Topics: Anti-Anxiety Agents; Anxiety; Breathing Exercises; Comorbidity; Death; Dibenzothiazepines; Eye Movem | 2012 |
Mirtazapine use in two pregnant women: is it safe?
Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety; Depression; Drug Therapy, Combination; Female; Fol | 2002 |
Attenuation of benzodiazepine withdrawal anxiety in the rat by serotonin antagonists.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Interpers | 2005 |
A case of mirtazapine-induced spontaneous orgasms in a female patient.
Topics: Antidepressive Agents, Tricyclic; Anxiety; Depressive Disorder; Female; Hospitals, Psychiatric; Huma | 2009 |
[Differentiated approach to the therapy of endogenous anxious depression].
Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety; Carbon Radioisotopes; Depression; Female; Follow-U | 2007 |
Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels.
Topics: Acetylcholinesterase; Amygdala; Animals; Anxiety; Autoradiography; Behavior, Animal; Binding Sites; | 1994 |
Potential role of 5HT1C and/or 5HT2 receptors in the mianserin-induced prevention of anxiogenic behaviors occurring during ethanol withdrawal.
Topics: Alcohol Withdrawal Delirium; Animals; Anxiety; Arousal; Brain; Discrimination Learning; Dose-Respons | 1993 |
A comparative study of the effects of selective and non-selective 5-HT2 receptor subtype antagonists in rat and mouse models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Drinking; Fluorobenzenes; Indoles | 1997 |
Safety in overdose of mirtazapine: a case report.
Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety; Confusion; Depressive Disorder; Dothiepin; Drug Ov | 1997 |
Clinical pharmacology of mirtazapine: revisited.
Topics: Agranulocytosis; Antidepressive Agents, Tricyclic; Anxiety; Depression; Humans; Mianserin; Mirtazapi | 1999 |
Inhibition of stress- or anxiogenic-drug-induced increases in dopamine release in the rat prefrontal cortex by long-term treatment with antidepressant drugs.
Topics: Animals; Antidepressive Agents; Anxiety; Carbolines; Dopamine; Dose-Response Relationship, Drug; Dru | 2001 |
An investigation of the mechanisms responsible for acute fluoxetine-induced anxiogenic-like effects in mice.
Topics: Animals; Anxiety; Arousal; Buspirone; Diazepam; Exploratory Behavior; Fluoxetine; Humans; Male; Mian | 2001 |
Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Carbolines; Cerebral Cortex | 2002 |
Acute and chronic hypertensive headache and hypertensive encephalopathy.
Topics: Acute Disease; Antidepressive Agents; Antihypertensive Agents; Anxiety; Arterioles; Cerebral Arterie | 2002 |
Mianserin in the treatment of ethanol withdrawal in the rat: prevention of behaviors indicative of anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Ethanol; Male; Mianserin; Rats; Substance Withdrawal Syndrome | 1991 |