mianserin has been researched along with Allodynia in 7 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was designed to explore the effects and most appropriate dosage of mirtazapine in treating neuropathic pain and its possible neuroimmune mechanisms." | 5.35 | Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain. ( Feng, X; Hu, Y; Song, J; Wei, X; Xu, J; Zhu, J, 2008) |
| "The effect of mianserin on hyperalgesia occurring in connection with peripheral diabetic neuropathy was examined using the Randall-Selitto (mechanical nociceptive stimulus), Hargreaves (thermal nociceptive stimulus), and cold-plate (4°C, thermal nociceptive stimulus) tests." | 1.42 | Antihyperalgesic and antiallodynic effects of mianserin on diabetic neuropathic pain: a study on mechanism of action. ( Can, ÖD; Demir Özkay, Ü; Öztürk, Y; Üçel, Uİ, 2015) |
| "Mirtazapine (MTZ) is an antidepressant, which is considered to enhance noradrenergic and serotonergic neurotransmission via antagonistic action at central α2-adrenergic autoreceptors and heteroreceptors." | 1.38 | Effects of mirtazapine on sleep disturbance under neuropathic pain-like state. ( Enomoto, T; Hirayama, S; Horiuchi, H; Ikegami, D; Inada, E; Iseki, M; Nagase, H; Nakahara, K; Narita, M; Sakai, H; Suzuki, T; Torigoe, K; Yamashita, A; Yanase, M, 2012) |
| " All substances were dosed between 0." | 1.35 | Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats. ( Driehsen, C; Freynhagen, R; Hermanns, H; Lipfert, P; Muth-Selbach, U, 2009) |
| "Mirtazapine was orally administered to rats that had been operated on daily for 14 days." | 1.35 | Interaction of glia activation and neurotransmission in hippocampus of neuropathic rats treated with mirtazapine. ( Hu, Y; Liu, J; Wei, X; Xu, J; Zhu, J, 2009) |
| " The present study was designed to explore the effects and most appropriate dosage of mirtazapine in treating neuropathic pain and its possible neuroimmune mechanisms." | 1.35 | Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain. ( Feng, X; Hu, Y; Song, J; Wei, X; Xu, J; Zhu, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X | 1 |
| Zhang, G | 1 |
| Dong, L | 1 |
| Wang, X | 1 |
| Sun, H | 1 |
| Shen, J | 1 |
| Li, W | 1 |
| Xu, J | 3 |
| Üçel, Uİ | 1 |
| Can, ÖD | 1 |
| Demir Özkay, Ü | 1 |
| Öztürk, Y | 1 |
| Muth-Selbach, U | 1 |
| Hermanns, H | 1 |
| Driehsen, C | 1 |
| Lipfert, P | 1 |
| Freynhagen, R | 1 |
| Zhu, J | 2 |
| Wei, X | 2 |
| Liu, J | 1 |
| Hu, Y | 2 |
| Enomoto, T | 1 |
| Yamashita, A | 1 |
| Torigoe, K | 1 |
| Horiuchi, H | 1 |
| Hirayama, S | 1 |
| Nakahara, K | 1 |
| Yanase, M | 1 |
| Sakai, H | 1 |
| Ikegami, D | 1 |
| Nagase, H | 1 |
| Suzuki, T | 1 |
| Iseki, M | 1 |
| Inada, E | 1 |
| Narita, M | 1 |
| Feng, X | 1 |
| Song, J | 1 |
| Kudriashova, MF | 1 |
| Andreev, BV | 1 |
7 other studies available for mianserin and Allodynia
| Article | Year |
|---|---|
Repeated administration of mirtazapine attenuates oxaliplatin-induced mechanical allodynia and spinal NR2B up-regulation in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Hyperalgesia; Mianserin; Mirtazapine; Organoplatinum Comp | 2013 |
Antihyperalgesic and antiallodynic effects of mianserin on diabetic neuropathic pain: a study on mechanism of action.
Topics: Analgesics; Animals; Catecholamines; Diabetic Neuropathies; Hyperalgesia; Male; Mianserin; Neuralgia | 2015 |
Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats.
Topics: Analgesics; Animals; Antidepressive Agents; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; | 2009 |
Interaction of glia activation and neurotransmission in hippocampus of neuropathic rats treated with mirtazapine.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Astrocytes; Glial Fibrillary Acidic Protein; | 2009 |
Effects of mirtazapine on sleep disturbance under neuropathic pain-like state.
Topics: Animals; Disease Models, Animal; Histamine H1 Antagonists; Hyperalgesia; Male; Mianserin; Mice; Mice | 2012 |
Repeated administration of mirtazapine inhibits development of hyperalgesia/allodynia and activation of NF-kappaB in a rat model of neuropathic pain.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cytokines; Denervation; Disease Models, Animal; Do | 2008 |
[Neuropharmacological analysis of participation of the serotoninergic system in hyperalgesia in neurotized rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Buspirone; Fluoxetine; Hyperalgesia; Male; Mian | 2000 |