Page last updated: 2024-10-31

mianserin and Alcohol Abuse

mianserin has been researched along with Alcohol Abuse in 13 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Research Excerpts

ExcerptRelevanceReference
"Mirtazapine was tolerated better than amitriptyline treatment."6.73Effectiveness and tolerability of mirtazapine and amitriptyline in alcoholic patients with co-morbid depressive disorder: a randomized, double-blind study. ( Akdeniz, F; Altintoprak, AE; Coskunol, H; Kitapcioglu, G; Zorlu, N, 2008)
"Major depressive disorder and alcohol dependence are common and serious mental illnesses."6.72Mirtazapine for patients with alcohol dependence and comorbid depressive disorders: a multicentre, open label study. ( Cho, SN; Choi, SB; Hwang, IB; Jeong, YC; Kim, DJ; Kim, JH; Lee, CT; Lee, E; Lee, HK; Lee, YS; Namkoong, K; Oh, DY; Pae, CU; Shin, DH; Shin, YC; Yoon, SJ, 2006)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."5.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)
"The objective of the present study was to determine whether a combined psychotherapeutic-psychopharmacological (with mirtazapine) treatment of collateral anxiety and depressive symptomatology during the post-withdrawal phase of alcoholism facilitates the process of alcohol detoxification, which is a decisive stage in the treatment of alcohol-dependent individuals."5.11Mirtazapine improves alcohol detoxification. ( Christodoulou, G; Liappas, J; Malitas, P; Paparrigopoulos, T; Tzavellas, E, 2004)
" The objective of the present study was to investigate: (a) the incidence of social anxiety symptoms in inpatient alcoholics, (b) the effect of alcohol detoxification on these symptoms, and (c) whether a combined psychotherapeutic/mirtazapine treatment during the post-detoxification phase of alcoholism has a greater impact on the aforementioned symptoms than a non-pharmacological approach."5.10Alcohol detoxification and social anxiety symptoms: a preliminary study of the impact of mirtazapine administration. ( Christodoulou, G; Liappas, J; Paparrigopoulos, T; Tzavellas, E, 2003)
"Mirtazapine was tolerated better than amitriptyline treatment."2.73Effectiveness and tolerability of mirtazapine and amitriptyline in alcoholic patients with co-morbid depressive disorder: a randomized, double-blind study. ( Akdeniz, F; Altintoprak, AE; Coskunol, H; Kitapcioglu, G; Zorlu, N, 2008)
"Major depressive disorder and alcohol dependence are common and serious mental illnesses."2.72Mirtazapine for patients with alcohol dependence and comorbid depressive disorders: a multicentre, open label study. ( Cho, SN; Choi, SB; Hwang, IB; Jeong, YC; Kim, DJ; Kim, JH; Lee, CT; Lee, E; Lee, HK; Lee, YS; Namkoong, K; Oh, DY; Pae, CU; Shin, DH; Shin, YC; Yoon, SJ, 2006)
"The drug also decreased alcohol addiction, had vegetostabilising and sedative effects."2.68[The efficacy and mechanisms of action of lerivon in alcoholism]. ( Anokhina, IP; Chirko, VV; Ivanets, NN; Kogan, BM; Nebarakova, TP; Rusinov, AV, 1996)
"A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine."1.43[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's7 (53.85)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atigari, OV1
Kelly, AM1
Jabeen, Q1
Healy, D1
Gentile, S1
Arora, S1
Vohora, D1
de Witte, LD1
Dekker, D1
Veraart, J1
Kromkamp, M1
Kaasjager, K1
Vinkers, CH1
Holt, C1
Butler, S1
Agius, M1
Zaman, R1
Liappas, J2
Paparrigopoulos, T2
Tzavellas, E2
Christodoulou, G2
Malitas, P1
Crockford, DN1
White, WD1
Yoon, SJ1
Pae, CU1
Kim, DJ1
Namkoong, K1
Lee, E1
Oh, DY1
Lee, YS1
Shin, DH1
Jeong, YC1
Kim, JH1
Choi, SB1
Hwang, IB1
Shin, YC1
Cho, SN1
Lee, HK1
Lee, CT1
Kitabayashi, Y1
Shibata, K1
Nakamae, T1
Narumoto, J1
Tani, N1
Fukui, K1
Altintoprak, AE1
Zorlu, N1
Coskunol, H1
Akdeniz, F1
Kitapcioglu, G1
Ivanets, NN1
Anokhina, IP1
Kogan, BM1
Chirko, VV1
Nebarakova, TP1
Rusinov, AV1
Sommer, M1
Dieterich, A1
Krause, C1
Rüther, E1
Wiltfang, J1

Reviews

1 review available for mianserin and Alcohol Abuse

ArticleYear
[Diagnosis, assessment, and treatment of alcohol withdrawal syndrome].
    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 2006, Volume: 41, Issue:6

    Topics: Alcohol-Related Disorders; Alcoholism; Antipsychotic Agents; Benzodiazepines; Diagnostic and Statist

2006

Trials

5 trials available for mianserin and Alcohol Abuse

ArticleYear
Alcohol detoxification and social anxiety symptoms: a preliminary study of the impact of mirtazapine administration.
    Journal of affective disorders, 2003, Volume: 76, Issue:1-3

    Topics: Adrenergic alpha-Antagonists; Adult; Alcoholism; Combined Modality Therapy; Female; Humans; Inactiva

2003
Mirtazapine improves alcohol detoxification.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Alcoholism; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Female;

2004
Mirtazapine for patients with alcohol dependence and comorbid depressive disorders: a multicentre, open label study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Sep-30, Volume: 30, Issue:7

    Topics: Adult; Alcoholism; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Female; Human

2006
Effectiveness and tolerability of mirtazapine and amitriptyline in alcoholic patients with co-morbid depressive disorder: a randomized, double-blind study.
    Human psychopharmacology, 2008, Volume: 23, Issue:4

    Topics: Adult; Alcoholism; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blin

2008
[The efficacy and mechanisms of action of lerivon in alcoholism].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1996, Volume: 96, Issue:5

    Topics: Adolescent; Adult; Alcohol Deterrents; Alcoholism; Amitriptyline; Anti-Anxiety Agents; Antidepressiv

1996

Other Studies

7 other studies available for mianserin and Alcohol Abuse

ArticleYear
New onset alcohol dependence linked to treatment with selective serotonin reuptake inhibitors.
    The International journal of risk & safety in medicine, 2013, Volume: 25, Issue:2

    Topics: Alcoholism; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Substitution; Female; Humans

2013
Pharmacological management of borderline personality disorder in a pregnant woman with a previous history of alcohol addiction: a case report.
    Clinical drug investigation, 2015, Volume: 35, Issue:11

    Topics: Adult; Alcoholism; Borderline Personality Disorder; Diagnosis, Dual (Psychiatry); Female; Humans; Mi

2015
Comparative Evaluation of Partial α2 -Adrenoceptor Agonist and Pure α2 -Adrenoceptor Antagonist on the Behavioural Symptoms of Withdrawal after Chronic Alcohol Administration in Mice.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Alcoholism; Animals; Anxiety; Be

2016
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
    Nederlands tijdschrift voor geneeskunde, 2016, Volume: 160

    Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans;

2016
An audit to compare patient factors (age, sex, social background & associated physical diagnoses) in people with refractory depression in a Bedfordshire Community Mental Health Team (BCMHT) being augmented with (A) mirtazepine, (B) atypical antipsychotics
    Psychiatria Danubina, 2011, Volume: 23 Suppl 1

    Topics: Adult; Age Distribution; Alcoholism; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Combine

2011
Mirtazapine for alcohol dependence: a case report.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:4

    Topics: Alcoholism; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Humans; Male; Mianse

2005
Subclinical pancreatitis related to mirtazapine - a case report.
    Pharmacopsychiatry, 2001, Volume: 34, Issue:4

    Topics: Alcoholism; Amylases; Antidepressive Agents, Tricyclic; Enzymes; Humans; Male; Mianserin; Middle Age

2001