mianserin has been researched along with Aggression in 14 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine." | 5.43 | [Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016) |
| "The aim of this study was to conduct a naturalistic, open-label examination of the efficacy and tolerability of mirtazapine (a medication with both serotonergic and noradrenergic properties) in the treatment of associated symptoms of autism and other pervasive developmental disorders (PDDs)." | 5.09 | A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders. ( Guenin, KD; Kohn, AE; McDougle, CJ; Posey, DJ; Swiezy, NB, 2001) |
| "A 23-year-old man with a history of alcohol dependence was admitted to our hospital after self-intoxication with 2700 mg baclofen and 330 mg mirtazapine." | 1.43 | [Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms]. ( de Witte, LD; Dekker, D; Kaasjager, K; Kromkamp, M; Veraart, J; Vinkers, CH, 2016) |
| "Mirtazapine (MIR) is an antidepressant which enhances noradrenergic and serotonergic 5-HT1A neurotransmission via antagomism of central alpha2-adrenergic autoreceptors and heteroreceptors." | 1.31 | Effect of repeated treatment with mirtazapine on the central alpha1-adrenergic receptors. ( Dlaboga, D; Dziedzicka-Wasylewska, M; Maj, J; Rogoz, Z; Wrobel, A, 2002) |
| "Phenelzine was the only antidepressant to increase aggression during encounters in the neutral cage after chronic administration." | 1.29 | Effects of acute and chronic administration of the antidepressants, imipramine, phenelzine and mianserin, on the social behaviour of mice. ( Cutler, MG; Gao, B, 1994) |
| " The effects observed indicate that the chronic administration of AD leads to the development of the increased responsiveness (or activation) of the noradrenergic system." | 1.26 | Atypical antidepressant drugs - psychopharmacological profile and mechanism of action. ( Maj, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Witte, LD | 1 |
| Dekker, D | 1 |
| Veraart, J | 1 |
| Kromkamp, M | 1 |
| Kaasjager, K | 1 |
| Vinkers, CH | 1 |
| Schoemaker, H | 1 |
| Berendsen, HH | 1 |
| Stevens, HJ | 1 |
| Nickolson, VJ | 2 |
| Mann, E | 1 |
| Enna, SJ | 1 |
| Wieringa, JH | 1 |
| van Delft, AM | 1 |
| Mogilnicka, E | 1 |
| Przewłocka, B | 1 |
| Maj, J | 2 |
| Gao, B | 1 |
| Cutler, MG | 1 |
| Cai, B | 1 |
| Matsumoto, K | 1 |
| Ohta, H | 1 |
| Watanabe, H | 1 |
| Tanum, L | 1 |
| Malt, UF | 1 |
| Posey, DJ | 1 |
| Guenin, KD | 1 |
| Kohn, AE | 1 |
| Swiezy, NB | 1 |
| McDougle, CJ | 1 |
| Rogoz, Z | 1 |
| Wrobel, A | 1 |
| Dlaboga, D | 1 |
| Dziedzicka-Wasylewska, M | 1 |
| Malick, JB | 1 |
| Barnett, A | 1 |
| Al-Khatib, IM | 1 |
| Fujiwara, M | 1 |
| Iwasaki, K | 1 |
| Kataoka, Y | 1 |
| Ueki, S | 1 |
| Niho, T | 1 |
| Ito, C | 1 |
| Shibutani, Y | 1 |
| Hashizume, H | 1 |
| Yamaguchi, K | 1 |
2 trials available for mianserin and Aggression
| Article | Year |
|---|---|
Personality traits predict treatment outcome with an antidepressant in patients with functional gastrointestinal disorder.
Topics: Adult; Aged; Aggression; Antidepressive Agents, Second-Generation; Colonic Diseases, Functional; Dys | 2000 |
A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders.
Topics: Adolescent; Adult; Aggression; Antidepressive Agents, Tricyclic; Anxiety Disorders; Appetite; Autist | 2001 |
12 other studies available for mianserin and Aggression
| Article | Year |
|---|---|
[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].
Topics: Adult; Aggression; Alcoholism; Baclofen; Delirium; Drug Overdose; GABA-B Receptor Agonists; Humans; | 2016 |
Differences in presynaptic alpha-blockade, noradrenaline uptake inhibition, and potential antidepressant activity between (+)- and (-)mianserin.
Topics: Adrenergic alpha-Antagonists; Aggression; Animals; Antidepressive Agents; Cerebral Cortex; Dibenzaze | 1981 |
Neurochemical and behavioral correlates of antidepressant drug action.
Topics: Aggression; Animals; Antidepressive Agents, Tricyclic; Atropine; Cerebral Cortex; Humans; Imipramine | 1982 |
Comparative pharmacology of mianserin, its main metabolites and 6-azamianserin.
Topics: Absorption; Aggression; Animals; Behavior, Animal; Brain; Cell Membrane; Clonidine; Dibenzazepines; | 1982 |
Facilitated shock-induced aggression after chronic treatment with antidepressant drugs in the rat.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Electroshock; Humans; Imiprami | 1981 |
Atypical antidepressant drugs - psychopharmacological profile and mechanism of action.
Topics: Aggression; Animals; Antidepressive Agents; Behavior, Animal; Drug Interactions; Humans; Iprindole; | 1982 |
Effects of acute and chronic administration of the antidepressants, imipramine, phenelzine and mianserin, on the social behaviour of mice.
Topics: Aggression; Animals; Antidepressive Agents; Drinking; Imipramine; Male; Mianserin; Mice; Motor Activ | 1994 |
Biphasic effects of typical antidepressants and mianserin, an atypical antidepressant, on aggressive behavior in socially isolated mice.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Clomipramine; Male; Mapr | 1993 |
Effect of repeated treatment with mirtazapine on the central alpha1-adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aggression; Animals; Antidepressive Agents, | 2002 |
The role of serotonergic pathways in isolation-induced aggression in mice.
Topics: 5-Hydroxytryptophan; Aggression; Amidines; Animals; Cinanserin; Cyproheptadine; Depression, Chemical | 1976 |
The role of brain catecholamines in the exhibition of muricide induced by nucleus accumbens lesions and the effect of antidepressants in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Antidepressive Agents; Brain; Dopamine; Imipram | 1987 |
[Pharmacological properties of MO-8282, a novel antidepressant].
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Amines; Brain; | 1986 |