mianserin has been researched along with Affective Disorders, Psychotic in 3 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Affective Disorders, Psychotic: Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general." | 7.66 | Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979) |
| "The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general." | 3.66 | Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perry, GF | 1 |
| Fitzsimmons, B | 1 |
| Shapiro, L | 1 |
| Irwin, P | 1 |
| Pichot, P | 1 |
| Dreyfus, JF | 1 |
| Pull, C | 1 |
| Zis, AP | 1 |
| Goodwin, FK | 1 |
2 trials available for mianserin and Affective Disorders, Psychotic
| Article | Year |
|---|---|
Clinical study of mianserin, imipramine and placebo in depression: blood level and MHPG correlations.
Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clinical Trials as To | 1978 |
A double-blind multicentre trial comparing mianserin with imipramine.
Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clinical Trials as To | 1978 |
1 other study available for mianserin and Affective Disorders, Psychotic
| Article | Year |
|---|---|
Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin.
Topics: Adjustment Disorders; Affective Disorders, Psychotic; Amitriptyline; Biogenic Amines; Brain; Depress | 1979 |