mianserin has been researched along with Adjustment Disorders in 12 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Adjustment Disorders: Maladaptive reactions to identifiable psychosocial stressors occurring within a short time after onset of the stressor. They are manifested by either impairment in social or occupational functioning or by symptoms (depression, anxiety, etc.) that are in excess of a normal and expected reaction to the stressor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of the present paper was to evaluate the effectiveness of mirtazapine orally disintegrating tablets for nausea and sleep disturbance, which are common and distressing symptoms of cancer." | 9.13 | Effectiveness of mirtazapine for nausea and insomnia in cancer patients with depression. ( Kim, JM; Kim, KM; Kim, KS; Kim, SW; Kim, YC; Shin, IS; Yang, SJ; Yoon, JS, 2008) |
| "The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general." | 7.66 | Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979) |
| " There were more withdrawals and dosage changes with nomifensine than with mianserin." | 6.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
| "The purpose of the present paper was to evaluate the effectiveness of mirtazapine orally disintegrating tablets for nausea and sleep disturbance, which are common and distressing symptoms of cancer." | 5.13 | Effectiveness of mirtazapine for nausea and insomnia in cancer patients with depression. ( Kim, JM; Kim, KM; Kim, KS; Kim, SW; Kim, YC; Shin, IS; Yang, SJ; Yoon, JS, 2008) |
| "This study aimed to compare the effectiveness of mirtazapine and imipramine on not only the distressing symptoms of cancer patients such as pain, nausea, vomiting, appetite loss, and sleep disturbances but also depressive and anxiety symptoms." | 5.13 | Mirtazapine improves sleep and lowers anxiety and depression in cancer patients: superiority over imipramine. ( Akbiyik, DI; Alkis, N; Cankurtaran, ES; Ozalp, E; Soygur, H; Turhan, L, 2008) |
| " Forty-six patients with moderate to severe degrees of depression were treated at random with mianserin or diazepam." | 5.04 | Comparative double-blind trial of mianserin hydrochloride (Organon GB94) and diazepam in patients with depressive illness. ( Niaz, U; Russell, GF; Slade, PD; Wakeling, A, 1978) |
| "The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general." | 3.66 | Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979) |
| " There were more withdrawals and dosage changes with nomifensine than with mianserin." | 2.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
| " Our quantitative pharmaco-EEG and clinical trials clearly demonstrated the significant value of quantitative EEG in early screening of psychoactive drugs in order to predict their clinical values and effective dosage ranges." | 1.25 | New drug developments in the Netherlands. "Tetracyclic" psychotropic drugs. ( Dincmen, K; Egilmez, S; Itil, TM; Polvan, N; Sungerbey, K, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Itil, TM | 1 |
| Polvan, N | 1 |
| Dincmen, K | 1 |
| Egilmez, S | 1 |
| Sungerbey, K | 1 |
| Kim, SW | 1 |
| Shin, IS | 1 |
| Kim, JM | 1 |
| Kim, YC | 1 |
| Kim, KS | 1 |
| Kim, KM | 1 |
| Yang, SJ | 1 |
| Yoon, JS | 1 |
| Cankurtaran, ES | 1 |
| Ozalp, E | 1 |
| Soygur, H | 1 |
| Akbiyik, DI | 1 |
| Turhan, L | 1 |
| Alkis, N | 1 |
| Tarrier, N | 1 |
| Maguire, P | 1 |
| Kincey, J | 1 |
| Launay, D | 1 |
| Queyrel, V | 1 |
| Hatron, PY | 1 |
| Michon-Pasturel, U | 1 |
| Caron, J | 1 |
| Hachulla, E | 1 |
| Devulder, B | 1 |
| Perry, GF | 1 |
| Fitzsimmons, B | 1 |
| Shapiro, L | 1 |
| Irwin, P | 1 |
| Russell, GF | 1 |
| Niaz, U | 1 |
| Wakeling, A | 1 |
| Slade, PD | 1 |
| Pichot, P | 1 |
| Dreyfus, JF | 1 |
| Pull, C | 1 |
| Zis, AP | 1 |
| Goodwin, FK | 1 |
| Coppen, A | 1 |
| Gupta, R | 1 |
| Montgomery, S | 1 |
| Ghose, K | 1 |
| Bailey, J | 1 |
| Burns, B | 1 |
| de Ridder, JJ | 1 |
| Granier, F | 1 |
| Girard, M | 1 |
| Schmitt, L | 1 |
| Boscredon, J | 1 |
| Oules, J | 1 |
| Escande, M | 1 |
| De Sousa, MP | 1 |
| Tropa, JR | 1 |
8 trials available for mianserin and Adjustment Disorders
| Article | Year |
|---|---|
Effectiveness of mirtazapine for nausea and insomnia in cancer patients with depression.
Topics: Adjustment Disorders; Administration, Oral; Adult; Aged; Antidepressive Agents, Tricyclic; Depressiv | 2008 |
Mirtazapine improves sleep and lowers anxiety and depression in cancer patients: superiority over imipramine.
Topics: Adaptation, Psychological; Adjustment Disorders; Adrenergic alpha-Antagonists; Adult; Antidepressive | 2008 |
Locus of control and cognitive behaviour therapy with mastectomy patients: a pilot study.
Topics: Adjustment Disorders; Behavior Therapy; Cognition; Combined Modality Therapy; Depressive Disorder; F | 1983 |
Clinical study of mianserin, imipramine and placebo in depression: blood level and MHPG correlations.
Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clinical Trials as To | 1978 |
Comparative double-blind trial of mianserin hydrochloride (Organon GB94) and diazepam in patients with depressive illness.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Diazepam; Diben | 1978 |
A double-blind multicentre trial comparing mianserin with imipramine.
Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clinical Trials as To | 1978 |
Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Bipolar Disorder; Depre | 1985 |
Comparative study of the therapeutic and adverse effects of two antidepressants--dothiepin and mianserin.
Topics: Adjustment Disorders; Adult; Aged; Circadian Rhythm; Depressive Disorder; Dibenzazepines; Dibenzothi | 1986 |
4 other studies available for mianserin and Adjustment Disorders
| Article | Year |
|---|---|
New drug developments in the Netherlands. "Tetracyclic" psychotropic drugs.
Topics: Adjustment Disorders; Anxiety Disorders; Bipolar Disorder; Brain; Clinical Trials as Topic; Dibenzox | 1974 |
[Agranulocytosis connected with the taking of mianserin: a complication to be feared in the aged].
Topics: Adjustment Disorders; Aged; Aged, 80 and over; Agranulocytosis; Antidepressive Agents, Second-Genera | 2000 |
Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin.
Topics: Adjustment Disorders; Affective Disorders, Psychotic; Amitriptyline; Biogenic Amines; Brain; Depress | 1979 |
Mianserin hydrochloride: a novel antidepressant.
Topics: Adjustment Disorders; Amitriptyline; Depression; Dibenzazepines; Drug Evaluation; Female; Humans; Ma | 1976 |