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mianserin and Acute Confusional Senile Dementia

mianserin has been researched along with Acute Confusional Senile Dementia in 13 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Research Excerpts

ExcerptRelevanceReference
"A 79-year old female patient with Alzheimer's disease developed acute dystonia twelve hours after taking a single dose of mirtazapine 30 mg."7.73[Mirtazapine-induced dystonia in a patient with Alzheimer's disease]. ( Bouckaert, F; Peuskens, J; van den Bosch, S, 2006)
"Three patients with dementia and depression complicated by weight loss, insomnia, and anxiety were treated with mirtazapine at an outpatient memory loss clinic of a university hospital."7.71Mirtazapine for treatment of depression and comorbidities in Alzheimer disease. ( Brady, SR; Raji, MA, 2001)
"A 79-year old female patient with Alzheimer's disease developed acute dystonia twelve hours after taking a single dose of mirtazapine 30 mg."3.73[Mirtazapine-induced dystonia in a patient with Alzheimer's disease]. ( Bouckaert, F; Peuskens, J; van den Bosch, S, 2006)
"Three patients with dementia and depression complicated by weight loss, insomnia, and anxiety were treated with mirtazapine at an outpatient memory loss clinic of a university hospital."3.71Mirtazapine for treatment of depression and comorbidities in Alzheimer disease. ( Brady, SR; Raji, MA, 2001)
"Treatment with mirtazapine or placebo had no effect on cognitive and functional status as assessed by the Mini-Mental State Examination and the Katz scale, respectively."2.84Mirtazapine does not improve sleep disorders in Alzheimer's disease: results from a double-blind, placebo-controlled pilot study. ( Camargos, EF; Louzada, LL; Naves, JO; Nóbrega, OT; Quintas, JL; Scoralick, FM, 2017)
"The prevalence of insomnia increases with age and affects up to 35% of community-dwelling adults with dementia."2.45Non-pharmacologic treatment of insomnia in persons with dementia. ( Darvishi, R; Kunik, ME; Shub, D, 2009)
"A 75-years-old man with Alzheimer's disease, treated with the cholinesterase inhibitor donepezil for 14 months, was scheduled for left colectomy under general anesthesia."1.32[Interaction of donepezil and muscular blockers in Alzheimer's disease]. ( Demartini Ferrari, A; Roca de Togores López, A; Sánchez Morillo, J, 2003)
"Of these disorders, depression is the most accessible of these to pharmacological treatment; agitation, however, raises the institutional problem."1.28Psychiatrists and Alzheimer's disease. ( Cazas, A; Flame, E; Ginestet, D, 1989)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's7 (53.85)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scoralick, FM1
Louzada, LL1
Quintas, JL1
Naves, JO1
Camargos, EF1
Nóbrega, OT1
Kálmán, J2
Shub, D1
Darvishi, R1
Kunik, ME1
Brodaty, H1
Banerjee, S1
Hellier, J1
Dewey, M1
Romeo, R1
Ballard, C1
Baldwin, R1
Bentham, P1
Fox, C1
Holmes, C1
Katona, C1
Knapp, M1
Lawton, C1
Lindesay, J1
Livingston, G1
McCrae, N1
Moniz-Cook, E1
Murray, J1
Nurock, S1
Orrell, M1
O'Brien, J1
Poppe, M1
Thomas, A1
Walwyn, R1
Wilson, K1
Burns, A1
Sepehry, AA1
Lee, PE1
Hsiung, GY1
Jacova, C1
Ahmed, A1
Sánchez Morillo, J1
Demartini Ferrari, A1
Roca de Togores López, A1
Palotás, A1
Puskás, LG1
Kitajka, K1
Palotás, M1
Molnár, J1
Pákáski, M1
Janka, Z1
Penke, B1
van den Bosch, S1
Bouckaert, F1
Peuskens, J1
Raji, MA1
Brady, SR1
Haupt, M1
Cazas, A1
Flame, E1
Ginestet, D1

Reviews

3 reviews available for mianserin and Acute Confusional Senile Dementia

ArticleYear
[Genomical and metabolomical abnormalities in Alzheimer disease and in experimental models].
    Ideggyogyaszati szemle, 2008, Jul-30, Volume: 61, Issue:7-8

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antidepressive Agents; Apolipoprotein E4

2008
Non-pharmacologic treatment of insomnia in persons with dementia.
    Geriatrics, 2009, Volume: 64, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Antidepressive Agents, Tricyclic; Circadian Rhyth

2009
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial.
    Lancet (London, England), 2011, Jul-30, Volume: 378, Issue:9789

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Do

2011

Trials

2 trials available for mianserin and Acute Confusional Senile Dementia

ArticleYear
Mirtazapine does not improve sleep disorders in Alzheimer's disease: results from a double-blind, placebo-controlled pilot study.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2017, Volume: 17, Issue:2

    Topics: Actigraphy; Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents, Tricyclic; Brazil; Do

2017
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial.
    Lancet (London, England), 2011, Jul-30, Volume: 378, Issue:9789

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Do

2011

Other Studies

9 other studies available for mianserin and Acute Confusional Senile Dementia

ArticleYear
Antidepressant treatment in Alzheimer's disease.
    Lancet (London, England), 2011, Jul-30, Volume: 378, Issue:9789

    Topics: Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Double-B

2011
Stay the course--is it justified?
    Lancet (London, England), 2012, Jan-21, Volume: 379, Issue:9812

    Topics: Alzheimer Disease; Antidepressive Agents; Dementia; Depressive Disorder; Female; Humans; Male; Menta

2012
Neutropenia associated with mirtazapine use: is a drop in the neutrophil count in a symptomatic older adults a cause for concern?
    Journal of the American Geriatrics Society, 2002, Volume: 50, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents, Tricyclic; Depression; Female; Hu

2002
[Interaction of donepezil and muscular blockers in Alzheimer's disease].
    Revista espanola de anestesiologia y reanimacion, 2003, Volume: 50, Issue:2

    Topics: Acetylcholine; Aged; Alzheimer Disease; Anesthesia, General; Atracurium; Cholinesterase Inhibitors;

2003
Altered response to mirtazapine on gene expression profile of lymphocytes from Alzheimer's patients.
    European journal of pharmacology, 2004, Aug-30, Volume: 497, Issue:3

    Topics: Aged; Alzheimer Disease; Antidepressive Agents, Tricyclic; Female; Gene Expression Profiling; Humans

2004
[Mirtazapine-induced dystonia in a patient with Alzheimer's disease].
    Tijdschrift voor psychiatrie, 2006, Volume: 48, Issue:2

    Topics: Acute Disease; Adrenergic alpha-Antagonists; Aged; Alzheimer Disease; Dystonia; Female; Humans; Mian

2006
Mirtazapine for treatment of depression and comorbidities in Alzheimer disease.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents, Tricyclic; Comorbidity; Depressio

2001
Depression in Alzheimer's disease significantly improved under treatment with mianserine.
    Journal of the American Geriatrics Society, 1991, Volume: 39, Issue:11

    Topics: Aged; Alzheimer Disease; Depression; Female; Humans; Mianserin

1991
Psychiatrists and Alzheimer's disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1989, Volume: 43, Issue:7

    Topics: Alzheimer Disease; Circadian Rhythm; Cognition; Dementia; Depression; Diagnosis, Differential; Human

1989