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mianserin and Acathisia, Drug-Induced

mianserin has been researched along with Acathisia, Drug-Induced in 20 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Research Excerpts

ExcerptRelevanceReference
"Thirty neuroleptic-treated patients with schizophrenia were randomly allocated in a double-blind design to receive either mianserin (15 mg/day) or placebo for five days."5.09Treatment of neuroleptic-induced akathisia with the 5-HT2 antagonist mianserin. Double-blind, placebo-controlled study. ( Fuchs, C; Poyurovsky, M; Schneidman, M; Shardorodsky, M; Weizman, A, 1999)
"Mirtazapine treatment was associated with modest improvement of psychotic and parkinsonian symptoms."2.71Efficacy of low-dose mirtazapine in neuroleptic-induced akathisia: a double-blind randomized placebo-controlled pilot study. ( Epshtein, S; Fuchs, C; Poyurovsky, M; Schneidman, M; Weizman, A; Weizman, R, 2003)
"Buspirone was effective in only two neuroleptic-induced akathisia patients and caused worsening of akathisia in the other two patients."2.68Serotonergic agents in the treatment of acute neuroleptic-induced akathisia: open-label study of buspirone and mianserin. ( Poyurovsky, M; Weizman, A, 1997)
"Mirtazapine was better tolerated than propranolol."1.35Role of mirtazapine in the treatment of antipsychotic-induced akathisia. ( Dellenbaugh, T; Hieber, R; Nelson, LA, 2008)
"Mirtazapine is a potent antagonist of central alpha(2) auto- and hetero-adrenergic receptors, as well as an antagonist of 5-HT(2A/2C), 5-HT(3), and histaminergic H(1) postsynaptic receptors."1.33Atypical antipsychotic-induced akathisia with depression: therapeutic role of mirtazapine. ( Chandra, PS; Chaturvedi, SK; Gupta, A; Prabhu, SC; Ranjan, S, 2006)
"Biperiden was transiently effective in the acute akathisia, while the more persistent akathisia was alleviated by mianserin."1.29Beneficial effect of low-dose mianserin on fluvoxamine-induced akathisia in an obsessive-compulsive patient. ( Meerovich, I; Poyurovsky, M; Weizman, A, 1995)
"Mianserin treatment (15 mg/day at 21."1.29Lithium-induced akathisia responds to low-dose mianserin: case report. ( Kreinin, A; Modai, I; Poyurovsky, M; Weizman, A, 1995)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (35.00)18.2507
2000's10 (50.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poyurovsky, M13
Bergman, J1
Pashinian, A2
Weizman, A12
Gulsun, M1
Doruk, A1
Aggarwal, A1
Khandelwal, A1
Garg, A1
Jiloha, RC1
Epshtein, S1
Fuchs, C4
Schneidman, M3
Weizman, R2
Wilson, MS1
Ranjan, S1
Chandra, PS1
Chaturvedi, SK1
Prabhu, SC1
Gupta, A1
Hieber, R1
Dellenbaugh, T1
Nelson, LA1
Meerovich, I1
Kosov, A1
Halperin, E1
Enoch, D1
Kreinin, A1
Modai, I1
Shardorodsky, M1
Westerlund, M1
Girishchandra, BG1
Johnson, L1
Cresp, RM1
Orr, KG1

Trials

5 trials available for mianserin and Acathisia, Drug-Induced

ArticleYear
Efficacy of low-dose mirtazapine in neuroleptic-induced akathisia: a double-blind randomized placebo-controlled pilot study.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Antipsychotic Agents; Chi-Square Distribution;

2003
Low-dose mirtazapine: a new option in the treatment of antipsychotic-induced akathisia. A randomized, double-blind, placebo- and propranolol-controlled trial.
    Biological psychiatry, 2006, Jun-01, Volume: 59, Issue:11

    Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents, Tr

2006
Serotonergic agents in the treatment of acute neuroleptic-induced akathisia: open-label study of buspirone and mianserin.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:5

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Buspirone; Female; Humans; Male

1997
Low-dose mianserin in treatment of acute neuroleptic-induced akathisia.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Female; Haloperidol; Humans; Male; Mianserin;

1998
Treatment of neuroleptic-induced akathisia with the 5-HT2 antagonist mianserin. Double-blind, placebo-controlled study.
    The British journal of psychiatry : the journal of mental science, 1999, Volume: 174

    Topics: Adult; Akathisia, Drug-Induced; Double-Blind Method; Female; Humans; Male; Mianserin; Schizophrenia;

1999

Other Studies

15 other studies available for mianserin and Acathisia, Drug-Induced

ArticleYear
Beneficial effect of low-dose mirtazapine in acute aripiprazole-induced akathisia.
    International clinical psychopharmacology, 2014, Volume: 29, Issue:5

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Arip

2014
Mirtazapine-induced akathisia.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Depr

2008
Acute antipsychotic-induced akathisia revisited.
    The British journal of psychiatry : the journal of mental science, 2010, Volume: 196, Issue:2

    Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Humans; Mianserin; Mirtazapine; Practi

2010
Akathisia associated with mianserin.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:3

    Topics: Akathisia, Drug-Induced; Depressive Disorder; Humans; Male; Mianserin; Middle Aged

2010
Mirtazapine for akathisia in bipolar disorder.
    Journal of clinical psychopharmacology, 2005, Volume: 25, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Male; Mianse

2005
Atypical antipsychotic-induced akathisia with depression: therapeutic role of mirtazapine.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Female; Humans; Male; Mianser

2006
Role of mirtazapine in the treatment of antipsychotic-induced akathisia.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Akathisia, Drug-Induced; Antipsychotic Ag

2008
Beneficial effect of low-dose mianserin on fluvoxamine-induced akathisia in an obsessive-compulsive patient.
    International clinical psychopharmacology, 1995, Volume: 10, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Biperiden; Fluvoxamine; Follow-Up Studies; Humans; Male; Mianserin;

1995
Akathisia-like behavior following ECT, and its successful treatment with low-dose mianserin.
    International clinical psychopharmacology, 1995, Volume: 10, Issue:4

    Topics: Akathisia, Drug-Induced; Electroconvulsive Therapy; Female; Follow-Up Studies; Humans; Mianserin; Mi

1995
Lithium-induced akathisia responds to low-dose mianserin: case report.
    International clinical psychopharmacology, 1995, Volume: 10, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Follow-Up Studies; Humans; Lithium; Male; Mianserin; Treatment Outco

1995
Selective serotonin reuptake inhibitor and akathisia.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:6

    Topics: Akathisia, Drug-Induced; Biperiden; Depressive Disorder; Histamine H1 Antagonists; Humans; Mianserin

1997
[A case report. Improvement in a patient with severe akathisia achieved by mianserin].
    Lakartidningen, 2000, Oct-04, Volume: 97, Issue:40

    Topics: Adrenergic alpha-Antagonists; Adult; Akathisia, Drug-Induced; Histamine H1 Antagonists; Humans; Male

2000
Mirtazapine for neuroleptic-induced akathisia.
    The American journal of psychiatry, 2001, Volume: 158, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Haloperidol; Hum

2001
Serotonin-based pharmacotherapy for acute neuroleptic-induced akathisia: a new approach to an old problem.
    The British journal of psychiatry : the journal of mental science, 2001, Volume: 179

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Buspirone; Clinical Trials as Topic; Cyproheptadine;

2001
Mirtazapine-induced akathisia.
    The Medical journal of Australia, 2002, Mar-04, Volume: 176, Issue:5

    Topics: Aged; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Female; Humans; Male; Mianserin; Mi

2002