mexiletine has been researched along with Wolff-Parkinson-White Syndrome in 8 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Wolff-Parkinson-White Syndrome: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disopyramide was first infused intravenously at 1 mg kg-1 for 5 min followed by a continuous infusion at 0." | 5.28 | Effects of a combination of disopyramide and mexiletine on the anterograde accessory pathway conduction in patients with Wolff-Parkinson-White syndrome. ( Aihara, N; Kamakura, S; Kurita, T; Matsuhisa, M; Ohe, T; Shimizu, W; Shimomura, K; Takaki, H, 1992) |
| "mexiletine did not cause any significant changes in the normal AV conduction pathway; 2." | 5.26 | [Effects of mexiletine in the Wolff-Parkinson-White syndrome]. ( Atallah, G; Gressard, A; Kirkorian, G; Touboul, P, 1981) |
| "Disopyramide was first infused intravenously at 1 mg kg-1 for 5 min followed by a continuous infusion at 0." | 1.28 | Effects of a combination of disopyramide and mexiletine on the anterograde accessory pathway conduction in patients with Wolff-Parkinson-White syndrome. ( Aihara, N; Kamakura, S; Kurita, T; Matsuhisa, M; Ohe, T; Shimizu, W; Shimomura, K; Takaki, H, 1992) |
| "mexiletine did not cause any significant changes in the normal AV conduction pathway; 2." | 1.26 | [Effects of mexiletine in the Wolff-Parkinson-White syndrome]. ( Atallah, G; Gressard, A; Kirkorian, G; Touboul, P, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menozzi, C | 1 |
| Lolli, G | 1 |
| Monducci, I | 1 |
| Gheller, G | 1 |
| Brignole, M | 1 |
| Cattabiani, ML | 1 |
| Vergoni, W | 1 |
| Barone, A | 1 |
| Touboul, P | 1 |
| Gressard, A | 1 |
| Kirkorian, G | 1 |
| Atallah, G | 1 |
| Neumann, G | 1 |
| Grube, E | 1 |
| Funke, H | 1 |
| Perrenoud, JJ | 1 |
| Coumel, P | 1 |
| Krikler, D | 1 |
| Rosen, MR | 1 |
| Wellens, HJ | 1 |
| Zipes, DP | 1 |
| McComish, M | 1 |
| Kitson, D | 1 |
| Robinson, C | 1 |
| Jewitt, DE | 1 |
| Shimizu, W | 1 |
| Ohe, T | 1 |
| Kurita, T | 1 |
| Takaki, H | 1 |
| Aihara, N | 1 |
| Kamakura, S | 1 |
| Matsuhisa, M | 1 |
| Shimomura, K | 1 |
| Róna, G | 1 |
1 review available for mexiletine and Wolff-Parkinson-White Syndrome
| Article | Year |
|---|---|
[Utilization of anti-arrhythmic drugs].
Topics: Action Potentials; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Digital | 1980 |
7 other studies available for mexiletine and Wolff-Parkinson-White Syndrome
| Article | Year |
|---|---|
[Antiarrhythmic efficacy of mexiletine in supraventricular arrhythmias, Wolff-Parkinson-White syndrome and persistent iterative ventricular hyperkinetic arrhythmias. Considerations on these less noted therapeutic effects].
Topics: Adult; Aged; Arrhythmias, Cardiac; Child; Drug Evaluation; Female; Humans; Male; Mexiletine; Middle | 1984 |
[Effects of mexiletine in the Wolff-Parkinson-White syndrome].
Topics: Adult; Female; Heart Conduction System; Humans; Male; Mexiletine; Propylamines; Wolff-Parkinson-Whit | 1981 |
[The value of antitachycardia pacemaker therapy in patients with Wolff-Parkinson-White syndrome].
Topics: Anti-Arrhythmia Agents; Bundle of His; Digitalis Glycosides; Disopyramide; Electrocardiography; Huma | 1983 |
Newer antiarrhythmic drugs.
Topics: Administration, Oral; Adult; Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Ca | 1978 |
Clinical electrophysiological effects of mexiletine.
Topics: Adolescent; Adult; Aged; Coronary Disease; Depression, Chemical; Female; Heart Conduction System; Hu | 1977 |
Effects of a combination of disopyramide and mexiletine on the anterograde accessory pathway conduction in patients with Wolff-Parkinson-White syndrome.
Topics: Adult; Atrial Fibrillation; Cardiac Pacing, Artificial; Disopyramide; Dose-Response Relationship, Dr | 1992 |
[Treatment of atrial fibrillation with mexiletine in Wolff-Parkinson-White syndrome].
Topics: Adult; Aged; Atrial Fibrillation; Cardiac Pacing, Artificial; Combined Modality Therapy; Electrocard | 1986 |