Page last updated: 2024-10-31

mexiletine and Syndrome

mexiletine has been researched along with Syndrome in 11 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
" He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia."7.76A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010)
"The treatment with lidocaine followed by mexiletine was useful for controlling clusters of intractable seizures."5.30[A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome]. ( Miyamoto, A; Oki, J; Takahashi, S, 1999)
"Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness."5.28Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990)
" He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia."3.76A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010)
"Myotonia is a skeletal muscle condition characterized by the over-excitability of the sarcolemma, resulting in delayed relaxation after contraction and muscle stiffness."3.01Blockers of Skeletal Muscle Na ( Boccanegra, B; Cerchiara, AG; De Bellis, M; De Luca, A; Imbrici, P, 2023)
"Brugada syndrome is characterized by an ST segment elevation in leads V1-V3 and a high incidence of ventricular fibrillation (VF)."2.69Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. ( Aihara, N; Antzelevitch, C; Kamakura, S; Kurita, T; Shimizu, W; Sunagawa, K; Suyama, K; Taguchi, A; Takaki, H, 2000)
"The treatment with lidocaine followed by mexiletine was useful for controlling clusters of intractable seizures."1.30[A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome]. ( Miyamoto, A; Oki, J; Takahashi, S, 1999)
"Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness."1.28Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's3 (27.27)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
De Bellis, M2
Boccanegra, B1
Cerchiara, AG1
Imbrici, P1
De Luca, A1
Camerino, DC1
Desaphy, JF1
Lee, SP1
Kim, SH1
Kim, TH1
Sohn, JW1
Shin, DH1
Park, SS1
Yoon, HJ1
Márquez, MF1
Salica, G1
Hermosillo, AG1
Pastelín, G1
Cárdenas, M1
Tan, BH1
Valdivia, CR1
Song, C1
Makielski, JC1
Yagami, A1
Yoshikawa, T1
Asano, Y1
Koie, S1
Shiohara, T1
Matsunaga, K1
Miyazaki, T1
Mitamura, H1
Miyoshi, S1
Soejima, K1
Aizawa, Y1
Ogawa, S1
Miyamoto, A1
Takahashi, S1
Oki, J1
Shimizu, W1
Antzelevitch, C1
Suyama, K1
Kurita, T1
Taguchi, A1
Aihara, N1
Takaki, H1
Sunagawa, K1
Kamakura, S1
Awerbuch, GI1
Sandyk, R1
Golikov, AP1
Rudnev, DV1

Reviews

2 reviews available for mexiletine and Syndrome

ArticleYear
Blockers of Skeletal Muscle Na
    International journal of molecular sciences, 2023, Jan-03, Volume: 24, Issue:1

    Topics: Humans; Mexiletine; Muscle, Skeletal; Myotonia; NAV1.4 Voltage-Gated Sodium Channel; Syndrome; Volta

2023
Drug therapy in Brugada syndrome.
    Current drug targets. Cardiovascular & haematological disorders, 2005, Volume: 5, Issue:5

    Topics: Bundle-Branch Block; Cilostazol; Electrocardiography; Humans; Isoproterenol; Mexiletine; Sotalol; Sy

2005

Trials

1 trial available for mexiletine and Syndrome

ArticleYear
Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2000, Volume: 11, Issue:12

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Disopyramide; Electrocardiography; Flecain

2000

Other Studies

8 other studies available for mexiletine and Syndrome

ArticleYear
Toward precision medicine in myotonic syndromes.
    Oncotarget, 2017, Feb-28, Volume: 8, Issue:9

    Topics: Amines; Animals; Anti-Arrhythmia Agents; Chloride Channels; Humans; Ligands; Mexiletine; Mice; Muscl

2017
A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia.
    Journal of Korean medical science, 2010, Volume: 25, Issue:1

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Drug Hyper

2010
Partial expression defect for the SCN5A missense mutation G1406R depends on splice variant background Q1077 and rescue by mexiletine.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:4

    Topics: Alternative Splicing; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Line; Gene Expression Regul

2006
Drug-induced hypersensitivity syndrome due to mexiletine hydrochloride associated with reactivation of human herpesvirus 7.
    Dermatology (Basel, Switzerland), 2006, Volume: 213, Issue:4

    Topics: Anti-Arrhythmia Agents; Antibodies, Viral; DNA, Viral; Drug Eruptions; Drug Hypersensitivity; Herpes

2006
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.
    Journal of the American College of Cardiology, 1996, Volume: 27, Issue:5

    Topics: Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Humans;

1996
[A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome].
    No to hattatsu = Brain and development, 1999, Volume: 31, Issue:5

    Topics: Administration, Oral; Adolescent; Epilepsies, Myoclonic; Epilepsy, Absence; Epilepsy, Generalized; H

1999
Mexiletine for thalamic pain syndrome.
    The International journal of neuroscience, 1990, Volume: 55, Issue:2-4

    Topics: Cerebral Hemorrhage; Cerebral Infarction; Female; Humans; Male; Mexiletine; Middle Aged; Multiple Sc

1990
[Reperfusion syndrome during thrombolytic therapy of myocardial infarct].
    Kardiologiia, 1989, Volume: 29, Issue:11

    Topics: Arrhythmias, Cardiac; Female; Fibrinolytic Agents; Hemodynamics; Humans; Male; Mexiletine; Middle Ag

1989