mexiletine has been researched along with Syndrome in 11 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia." | 7.76 | A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010) |
| "The treatment with lidocaine followed by mexiletine was useful for controlling clusters of intractable seizures." | 5.30 | [A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome]. ( Miyamoto, A; Oki, J; Takahashi, S, 1999) |
| "Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness." | 5.28 | Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990) |
| " He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia." | 3.76 | A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010) |
| "Myotonia is a skeletal muscle condition characterized by the over-excitability of the sarcolemma, resulting in delayed relaxation after contraction and muscle stiffness." | 3.01 | Blockers of Skeletal Muscle Na ( Boccanegra, B; Cerchiara, AG; De Bellis, M; De Luca, A; Imbrici, P, 2023) |
| "Brugada syndrome is characterized by an ST segment elevation in leads V1-V3 and a high incidence of ventricular fibrillation (VF)." | 2.69 | Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. ( Aihara, N; Antzelevitch, C; Kamakura, S; Kurita, T; Shimizu, W; Sunagawa, K; Suyama, K; Taguchi, A; Takaki, H, 2000) |
| "The treatment with lidocaine followed by mexiletine was useful for controlling clusters of intractable seizures." | 1.30 | [A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome]. ( Miyamoto, A; Oki, J; Takahashi, S, 1999) |
| "Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness." | 1.28 | Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| De Bellis, M | 2 |
| Boccanegra, B | 1 |
| Cerchiara, AG | 1 |
| Imbrici, P | 1 |
| De Luca, A | 1 |
| Camerino, DC | 1 |
| Desaphy, JF | 1 |
| Lee, SP | 1 |
| Kim, SH | 1 |
| Kim, TH | 1 |
| Sohn, JW | 1 |
| Shin, DH | 1 |
| Park, SS | 1 |
| Yoon, HJ | 1 |
| Márquez, MF | 1 |
| Salica, G | 1 |
| Hermosillo, AG | 1 |
| Pastelín, G | 1 |
| Cárdenas, M | 1 |
| Tan, BH | 1 |
| Valdivia, CR | 1 |
| Song, C | 1 |
| Makielski, JC | 1 |
| Yagami, A | 1 |
| Yoshikawa, T | 1 |
| Asano, Y | 1 |
| Koie, S | 1 |
| Shiohara, T | 1 |
| Matsunaga, K | 1 |
| Miyazaki, T | 1 |
| Mitamura, H | 1 |
| Miyoshi, S | 1 |
| Soejima, K | 1 |
| Aizawa, Y | 1 |
| Ogawa, S | 1 |
| Miyamoto, A | 1 |
| Takahashi, S | 1 |
| Oki, J | 1 |
| Shimizu, W | 1 |
| Antzelevitch, C | 1 |
| Suyama, K | 1 |
| Kurita, T | 1 |
| Taguchi, A | 1 |
| Aihara, N | 1 |
| Takaki, H | 1 |
| Sunagawa, K | 1 |
| Kamakura, S | 1 |
| Awerbuch, GI | 1 |
| Sandyk, R | 1 |
| Golikov, AP | 1 |
| Rudnev, DV | 1 |
2 reviews available for mexiletine and Syndrome
| Article | Year |
|---|---|
Blockers of Skeletal Muscle Na
Topics: Humans; Mexiletine; Muscle, Skeletal; Myotonia; NAV1.4 Voltage-Gated Sodium Channel; Syndrome; Volta | 2023 |
Drug therapy in Brugada syndrome.
Topics: Bundle-Branch Block; Cilostazol; Electrocardiography; Humans; Isoproterenol; Mexiletine; Sotalol; Sy | 2005 |
1 trial available for mexiletine and Syndrome
| Article | Year |
|---|---|
Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Disopyramide; Electrocardiography; Flecain | 2000 |
8 other studies available for mexiletine and Syndrome
| Article | Year |
|---|---|
Toward precision medicine in myotonic syndromes.
Topics: Amines; Animals; Anti-Arrhythmia Agents; Chloride Channels; Humans; Ligands; Mexiletine; Mice; Muscl | 2017 |
A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia.
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Drug Hyper | 2010 |
Partial expression defect for the SCN5A missense mutation G1406R depends on splice variant background Q1077 and rescue by mexiletine.
Topics: Alternative Splicing; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Line; Gene Expression Regul | 2006 |
Drug-induced hypersensitivity syndrome due to mexiletine hydrochloride associated with reactivation of human herpesvirus 7.
Topics: Anti-Arrhythmia Agents; Antibodies, Viral; DNA, Viral; Drug Eruptions; Drug Hypersensitivity; Herpes | 2006 |
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Humans; | 1996 |
[A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome].
Topics: Administration, Oral; Adolescent; Epilepsies, Myoclonic; Epilepsy, Absence; Epilepsy, Generalized; H | 1999 |
Mexiletine for thalamic pain syndrome.
Topics: Cerebral Hemorrhage; Cerebral Infarction; Female; Humans; Male; Mexiletine; Middle Aged; Multiple Sc | 1990 |
[Reperfusion syndrome during thrombolytic therapy of myocardial infarct].
Topics: Arrhythmias, Cardiac; Female; Fibrinolytic Agents; Hemodynamics; Humans; Male; Mexiletine; Middle Ag | 1989 |