mexiletine has been researched along with Syndrome in 11 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Syndrome: A characteristic symptom complex.
Excerpt | Relevance | Reference |
---|---|---|
" He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia." | 7.76 | A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010) |
"The treatment with lidocaine followed by mexiletine was useful for controlling clusters of intractable seizures." | 5.30 | [A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome]. ( Miyamoto, A; Oki, J; Takahashi, S, 1999) |
"Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness." | 5.28 | Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990) |
" He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia." | 3.76 | A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010) |
"Myotonia is a skeletal muscle condition characterized by the over-excitability of the sarcolemma, resulting in delayed relaxation after contraction and muscle stiffness." | 3.01 | Blockers of Skeletal Muscle Na ( Boccanegra, B; Cerchiara, AG; De Bellis, M; De Luca, A; Imbrici, P, 2023) |
"Brugada syndrome is characterized by an ST segment elevation in leads V1-V3 and a high incidence of ventricular fibrillation (VF)." | 2.69 | Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. ( Aihara, N; Antzelevitch, C; Kamakura, S; Kurita, T; Shimizu, W; Sunagawa, K; Suyama, K; Taguchi, A; Takaki, H, 2000) |
"The treatment with lidocaine followed by mexiletine was useful for controlling clusters of intractable seizures." | 1.30 | [A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome]. ( Miyamoto, A; Oki, J; Takahashi, S, 1999) |
"Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness." | 1.28 | Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (9.09) | 18.7374 |
1990's | 3 (27.27) | 18.2507 |
2000's | 4 (36.36) | 29.6817 |
2010's | 2 (18.18) | 24.3611 |
2020's | 1 (9.09) | 2.80 |
Authors | Studies |
---|---|
De Bellis, M | 2 |
Boccanegra, B | 1 |
Cerchiara, AG | 1 |
Imbrici, P | 1 |
De Luca, A | 1 |
Camerino, DC | 1 |
Desaphy, JF | 1 |
Lee, SP | 1 |
Kim, SH | 1 |
Kim, TH | 1 |
Sohn, JW | 1 |
Shin, DH | 1 |
Park, SS | 1 |
Yoon, HJ | 1 |
Márquez, MF | 1 |
Salica, G | 1 |
Hermosillo, AG | 1 |
Pastelín, G | 1 |
Cárdenas, M | 1 |
Tan, BH | 1 |
Valdivia, CR | 1 |
Song, C | 1 |
Makielski, JC | 1 |
Yagami, A | 1 |
Yoshikawa, T | 1 |
Asano, Y | 1 |
Koie, S | 1 |
Shiohara, T | 1 |
Matsunaga, K | 1 |
Miyazaki, T | 1 |
Mitamura, H | 1 |
Miyoshi, S | 1 |
Soejima, K | 1 |
Aizawa, Y | 1 |
Ogawa, S | 1 |
Miyamoto, A | 1 |
Takahashi, S | 1 |
Oki, J | 1 |
Shimizu, W | 1 |
Antzelevitch, C | 1 |
Suyama, K | 1 |
Kurita, T | 1 |
Taguchi, A | 1 |
Aihara, N | 1 |
Takaki, H | 1 |
Sunagawa, K | 1 |
Kamakura, S | 1 |
Awerbuch, GI | 1 |
Sandyk, R | 1 |
Golikov, AP | 1 |
Rudnev, DV | 1 |
2 reviews available for mexiletine and Syndrome
Article | Year |
---|---|
Blockers of Skeletal Muscle Na
Topics: Humans; Mexiletine; Muscle, Skeletal; Myotonia; NAV1.4 Voltage-Gated Sodium Channel; Syndrome; Volta | 2023 |
Drug therapy in Brugada syndrome.
Topics: Bundle-Branch Block; Cilostazol; Electrocardiography; Humans; Isoproterenol; Mexiletine; Sotalol; Sy | 2005 |
1 trial available for mexiletine and Syndrome
Article | Year |
---|---|
Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Disopyramide; Electrocardiography; Flecain | 2000 |
8 other studies available for mexiletine and Syndrome
Article | Year |
---|---|
Toward precision medicine in myotonic syndromes.
Topics: Amines; Animals; Anti-Arrhythmia Agents; Chloride Channels; Humans; Ligands; Mexiletine; Mice; Muscl | 2017 |
A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia.
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Drug Hyper | 2010 |
Partial expression defect for the SCN5A missense mutation G1406R depends on splice variant background Q1077 and rescue by mexiletine.
Topics: Alternative Splicing; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Line; Gene Expression Regul | 2006 |
Drug-induced hypersensitivity syndrome due to mexiletine hydrochloride associated with reactivation of human herpesvirus 7.
Topics: Anti-Arrhythmia Agents; Antibodies, Viral; DNA, Viral; Drug Eruptions; Drug Hypersensitivity; Herpes | 2006 |
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Humans; | 1996 |
[A successful treatment with intravenous lidocaine followed by oral mexiletine in a patient with Lennox-Gastaut syndrome].
Topics: Administration, Oral; Adolescent; Epilepsies, Myoclonic; Epilepsy, Absence; Epilepsy, Generalized; H | 1999 |
Mexiletine for thalamic pain syndrome.
Topics: Cerebral Hemorrhage; Cerebral Infarction; Female; Humans; Male; Mexiletine; Middle Aged; Multiple Sc | 1990 |
[Reperfusion syndrome during thrombolytic therapy of myocardial infarct].
Topics: Arrhythmias, Cardiac; Female; Fibrinolytic Agents; Hemodynamics; Humans; Male; Mexiletine; Middle Ag | 1989 |