mexiletine has been researched along with Subarachnoid Hemorrhage in 2 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mexiletine treatment prevented the increase in lipid peroxidation and cerebral vasospasm." | 5.33 | The effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. ( Altinors, N; Atalay, B; Aydin, MV; Bavbek, M; Caner, H; Ozen, O; Sen, O, 2006) |
| "Mexiletine treatment prevented the increase in lipid peroxidation and cerebral vasospasm." | 1.33 | The effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage. ( Altinors, N; Atalay, B; Aydin, MV; Bavbek, M; Caner, H; Ozen, O; Sen, O, 2006) |
| "Mexiletine is a class Ib drug that is widely used to treat ventricular arrhythmias." | 1.31 | Systemic administration of mexiletine for attenuation of cerebral vasospasm following experimental subarachnoid haemorrhage. ( Bavbek, M; Caner, H; Durieux, M; Kassell, NF; Kilinc, K; Kwan, AL; Lee, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, O | 1 |
| Caner, H | 2 |
| Aydin, MV | 1 |
| Ozen, O | 1 |
| Atalay, B | 1 |
| Altinors, N | 1 |
| Bavbek, M | 2 |
| Kwan, AL | 1 |
| Kilinc, K | 1 |
| Durieux, M | 1 |
| Lee, K | 1 |
| Kassell, NF | 1 |
2 other studies available for mexiletine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
The effect of mexiletine on the level of lipid peroxidation and apoptosis of endothelium following experimental subarachnoid hemorrhage.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Apoptosis; Arteries; Disease Models, Animal; | 2006 |
Systemic administration of mexiletine for attenuation of cerebral vasospasm following experimental subarachnoid haemorrhage.
Topics: Administration, Topical; Animals; Basilar Artery; Mexiletine; Rabbits; Reference Values; Subarachnoi | 2000 |