mexiletine has been researched along with Paralysis, Hyperkalemic Periodic in 2 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Paralysis, Hyperkalemic Periodic: An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fontaine, B | 1 |
| Weckbecker, K | 1 |
| Würz, A | 1 |
| Mohammadi, B | 1 |
| Mansuroglu, T | 1 |
| George, AL | 1 |
| Lerche, H | 1 |
| Dengler, R | 1 |
| Lehmann-Horn, F | 1 |
| Mitrovic, N | 1 |
1 review available for mexiletine and Paralysis, Hyperkalemic Periodic
| Article | Year |
|---|---|
[Ion-channel related muscular diseases].
Topics: Acetazolamide; Anti-Arrhythmia Agents; Anticonvulsants; Carbamazepine; Humans; Hypokalemic Periodic | 1999 |
1 other study available for mexiletine and Paralysis, Hyperkalemic Periodic
| Article | Year |
|---|---|
Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis.
Topics: Cell Line; Homeostasis; Humans; Mexiletine; Models, Molecular; Mutation; Myotonic Disorders; Paralys | 2000 |