mexiletine has been researched along with Pain, Postoperative in 5 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine treatment provided lower pain scores compared with placebo and mexiletine (P = 0." | 2.73 | Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial. ( Agarwal, S; Clark, MR; Haythornthwaite, JA; Klick, B; Max, MB; Raja, SN; Tella, PK; Wu, CL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaparro, LE | 1 |
| Smith, SA | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Gilron, I | 1 |
| Klass, M | 1 |
| Csete, M | 1 |
| Wu, CL | 1 |
| Agarwal, S | 1 |
| Tella, PK | 1 |
| Klick, B | 1 |
| Clark, MR | 1 |
| Haythornthwaite, JA | 1 |
| Max, MB | 1 |
| Raja, SN | 1 |
| Fassoulaki, A | 1 |
| Patris, K | 1 |
| Sarantopoulos, C | 1 |
| Hogan, Q | 1 |
| Morita, H | 1 |
| Higashizawa, T | 1 |
| Yuasa, H | 1 |
| Hiramatsu, K | 1 |
| Koga, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Placebo-Controlled, Double-Blind Cross-Over Trial of Opioids Versus Mexiletine in the Treatment of Postamputation Pain[NCT00383682] | Phase 2 | 60 participants | Interventional | 1997-07-31 | Completed | ||
| Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
| Comparative Evaluation of Osteopathy Treatment Efficacy in Pain Support After Breast Surgery in Oncology[NCT01403168] | 28 participants (Actual) | Interventional | 2011-04-30 | Terminated (stopped due to Recruitment difficulties) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mexiletine and Pain, Postoperative
| Article | Year |
|---|---|
Pharmacotherapy for the prevention of chronic pain after surgery in adults.
Topics: Adrenal Cortex Hormones; Adult; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Femal | 2013 |
3 trials available for mexiletine and Pain, Postoperative
| Article | Year |
|---|---|
Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial.
Topics: Amputation, Surgical; Anti-Arrhythmia Agents; Cross-Over Studies; Dose-Response Relationship, Drug; | 2008 |
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr | 2002 |
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr | 2002 |
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr | 2002 |
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chr | 2002 |
[Evaluation of preincisional mexiletine administration to alleviate postoperative pain].
Topics: Adult; Anesthesia, General; Anti-Arrhythmia Agents; Female; Humans; Infusions, Intravenous; Injectio | 1998 |
1 other study available for mexiletine and Pain, Postoperative
| Article | Year |
|---|---|
One from column A and one from column B: may I take your order?
Topics: Amines; Analgesics, Opioid; Anti-Arrhythmia Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A | 2008 |