mexiletine has been researched along with Nervous System Disorders in 5 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine and oral analogs were safe drugs in controlled clinical trials for neuropathic pain, were better than placebo, and were as effective as other analgesics." | 4.82 | Systemic administration of local anesthetic agents to relieve neuropathic pain. ( Carr, DB; Challapalli, V; Lau, J; McNicol, ED; Tremont-Lukats, IW, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Challapalli, V | 1 |
| Tremont-Lukats, IW | 1 |
| McNicol, ED | 1 |
| Lau, J | 1 |
| Carr, DB | 1 |
| Palileo, EV | 1 |
| Welch, W | 1 |
| Hoff, J | 1 |
| Strasberg, B | 1 |
| Bauernfeind, RA | 1 |
| Swiryn, S | 1 |
| Coelho, A | 1 |
| Rosen, KM | 1 |
| Christie, JM | 1 |
| Valdes, C | 1 |
| Markowsky, SJ | 1 |
| Petersen, P | 1 |
| Kastrup, J | 1 |
| Zeeberg, I | 1 |
| Boysen, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain : A Pilot Study[NCT02217267] | Phase 3 | 29 participants (Actual) | Interventional | 2014-08-01 | Completed | ||
| The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624] | Phase 4 | 80 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mexiletine and Nervous System Disorders
| Article | Year |
|---|---|
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Systemic administration of local anesthetic agents to relieve neuropathic pain.
Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; M | 2005 |
Drug treatment of neuropathic pain.
Topics: Aged; Analgesics, Opioid; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvu | 2000 |
1 trial available for mexiletine and Nervous System Disorders
| Article | Year |
|---|---|
Chronic pain treatment with intravenous lidocaine.
Topics: Double-Blind Method; Humans; Infusions, Intravenous; Lidocaine; Mexiletine; Nervous System Diseases; | 1986 |
2 other studies available for mexiletine and Nervous System Disorders
| Article | Year |
|---|---|
Lack of effectiveness of oral mexiletine in patients with drug-refractory paroxysmal sustained ventricular tachycardia. A study utilizing programmed stimulation.
Topics: Aged; Cardiac Catheterization; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Conduc | 1982 |
Neurotoxicity of lidocaine combined with mexiletine.
Topics: Administration, Oral; Cardiomyopathies; Drug Therapy, Combination; Humans; Injections, Intravenous; | 1993 |