Page last updated: 2024-10-31

mexiletine and Kidney Diseases

mexiletine has been researched along with Kidney Diseases in 3 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"The clinical relevance of changes in pharmacokinetics of oral mexiletine (600 mg daily dose) was studied in 82 patients with ventricular arrhythmias and impaired liver, renal or heart function (control group n = 51, patients with liver cirrhosis n = 9, with renal insufficiency n = 14, or heart failure n = 8)."3.66Increase of mexiletine plasma levels due to delayed hepatic metabolism in patients with chronic liver disease. ( Lüderitz, B; Nitsch, J; Steinbeck, G, 1983)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akhtar, M1
Nitsch, J1
Steinbeck, G1
Lüderitz, B1
Herbinger, W1
Kramar, R1
Fridrik, M1
Häselbarth, V1
Pollmann, WP1

Reviews

1 review available for mexiletine and Kidney Diseases

ArticleYear
Practical considerations in the treatment of ventricular arrhythmias with mexiletine.
    American heart journal, 1984, Volume: 107, Issue:5 Pt 2

    Topics: Adult; Aged; Animals; Arrhythmias, Cardiac; Dogs; Electrocardiography; Gastrointestinal Diseases; Hu

1984

Other Studies

2 other studies available for mexiletine and Kidney Diseases

ArticleYear
Increase of mexiletine plasma levels due to delayed hepatic metabolism in patients with chronic liver disease.
    European heart journal, 1983, Volume: 4, Issue:11

    Topics: Arrhythmias, Cardiac; Chronic Disease; Heart Failure; Humans; Kidney Diseases; Kinetics; Liver; Live

1983
[Pharmacokinetic studies with mexiletine in patients with renal insufficiency].
    Advances in clinical pharmacology, 1978, Volume: 16

    Topics: Adult; Female; Half-Life; Humans; Kidney Diseases; Mexiletine; Middle Aged; Propylamines; Time Facto

1978