Page last updated: 2024-10-31

mexiletine and Injuries, Spinal Cord

mexiletine has been researched along with Injuries, Spinal Cord in 5 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Research Excerpts

ExcerptRelevanceReference
"Mexiletine treatment improved early behavioral recovery after SCI."1.33Mexiletine treatment-induced inhibition of caspase-3 activation and improvement of behavioral recovery after spinal cord injury. ( Caner, H; Kaptanoglu, E; Kilinc, K; Solaroglu, I, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaptanoglu, E2
Caner, H1
Solaroglu, I1
Kilinc, K1
Ates, O1
Cayli, SR1
Gurses, I1
Turkoz, Y1
Tarim, O1
Cakir, CO1
Kocak, A1
Caner, HH1
Sürücü, HS1
Akbiyik, F1
Wu, WP1
Nordmark, J1
Wiesenfeld-Hallin, Z2
Xu, XJ2
Hao, JX1
Seiger, A1
Arnér, S1
Lindblom, U1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Cohort Study of Association Between Steady State Phenytoin Treatment and Better Clinical Parameters of Glaucoma[NCT00739154]200 participants (Anticipated)Observational2008-11-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for mexiletine and Injuries, Spinal Cord

ArticleYear
Mexiletine treatment-induced inhibition of caspase-3 activation and improvement of behavioral recovery after spinal cord injury.
    Journal of neurosurgery. Spine, 2005, Volume: 3, Issue:1

    Topics: Animals; Behavior, Animal; Caspase 3; Caspases; Enzyme Activation; Female; Hindlimb; Methylprednisol

2005
Comparative neuroprotective effect of sodium channel blockers after experimental spinal cord injury.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2007, Volume: 14, Issue:7

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Lipid Peroxidation; Locomotion; Male; Mexiletine;

2007
Effect of mexiletine on lipid peroxidation and early ultrastructural findings in experimental spinal cord injury.
    Journal of neurosurgery, 1999, Volume: 91, Issue:2 Suppl

    Topics: Analysis of Variance; Animals; Antioxidants; Lipid Peroxidation; Male; Methylprednisolone Hemisuccin

1999
Lack of stereoselectivity for the antiallodynic effect of mexiletine in spinally injured rats.
    European journal of pain (London, England), 2000, Volume: 4, Issue:4

    Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Drug Evaluation, Preclinical; Female;

2000
Systemic mexiletine relieves chronic allodynialike symptoms in rats with ischemic spinal cord injury.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:5

    Topics: Animals; Female; Injections, Intraperitoneal; Ischemia; Mexiletine; Motor Activity; Pain; Pain Measu

1992