mexiletine has been researched along with Infarction, Middle Cerebral Artery in 2 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Left middle cerebral artery occlusion following microcraniectomy and simultaneous bilateral carotid artery occlusion were performed." | 1.35 | The preventive effect of mexiletine on cerebral ischemic injury following experimental middle cerebral artery occlusion. ( Akar, A; Altinors, N; Caner, H; Cansever, T; Gulsen, S; Kabatas, S; Ozger, O; Yilmaz, C, 2009) |
| "Mexiletine treatment, on the other hand, had no significant effect on the down-regulation of either gene." | 1.32 | The sodium channel blocker RS100642 reverses down-regulation of the sodium channel alpha-subunit Na(v) 1.1 expression caused by transient ischemic brain injury in rats. ( Berti, R; Cunningham, BS; Dave, JR; Lu, XC; Price, RA; Tortella, FC; Williams, AJ; Yao, C, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yilmaz, C | 1 |
| Ozger, O | 1 |
| Kabatas, S | 1 |
| Cansever, T | 1 |
| Akar, A | 1 |
| Gulsen, S | 1 |
| Altinors, N | 1 |
| Caner, H | 1 |
| Yao, C | 1 |
| Williams, AJ | 1 |
| Lu, XC | 1 |
| Price, RA | 1 |
| Cunningham, BS | 1 |
| Berti, R | 1 |
| Tortella, FC | 1 |
| Dave, JR | 1 |
2 other studies available for mexiletine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
The preventive effect of mexiletine on cerebral ischemic injury following experimental middle cerebral artery occlusion.
Topics: Animals; Anti-Arrhythmia Agents; Brain Ischemia; Calcium Channel Blockers; Disease Models, Animal; I | 2009 |
The sodium channel blocker RS100642 reverses down-regulation of the sodium channel alpha-subunit Na(v) 1.1 expression caused by transient ischemic brain injury in rats.
Topics: Animals; Down-Regulation; Gene Expression; Infarction, Middle Cerebral Artery; Ischemic Attack, Tran | 2003 |