mexiletine has been researched along with Genetic Predisposition in 4 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thousands die each year from sudden infant death syndrome (SIDS)." | 1.33 | A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y. ( Bowers, PN; Chen, W; Goldstein, SA; Kittles, RA; Liu, Q; Morgan, T; Plant, LD; State, MW; Zhang, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, DW | 1 |
| Crotti, L | 1 |
| Shimizu, W | 1 |
| Pedrazzini, M | 1 |
| Cantu, F | 1 |
| De Filippo, P | 1 |
| Kishiki, K | 1 |
| Miyazaki, A | 1 |
| Ikeda, T | 1 |
| Schwartz, PJ | 1 |
| George, AL | 1 |
| Ruan, Y | 1 |
| Denegri, M | 1 |
| Liu, N | 1 |
| Bachetti, T | 1 |
| Seregni, M | 1 |
| Morotti, S | 1 |
| Severi, S | 1 |
| Napolitano, C | 1 |
| Priori, SG | 1 |
| Yoshikane, Y | 1 |
| Yoshinaga, M | 1 |
| Hamamoto, K | 1 |
| Hirose, S | 1 |
| Plant, LD | 1 |
| Bowers, PN | 1 |
| Liu, Q | 1 |
| Morgan, T | 1 |
| Zhang, T | 1 |
| State, MW | 1 |
| Chen, W | 1 |
| Kittles, RA | 1 |
| Goldstein, SA | 1 |
4 other studies available for mexiletine and Genetic Predisposition
| Article | Year |
|---|---|
Malignant perinatal variant of long-QT syndrome caused by a profoundly dysfunctional cardiac sodium channel.
Topics: Action Potentials; Anti-Arrhythmia Agents; DNA Mutational Analysis; Dose-Response Relationship, Drug | 2008 |
Trafficking defects and gating abnormalities of a novel SCN5A mutation question gene-specific therapy in long QT syndrome type 3.
Topics: Action Potentials; Anti-Arrhythmia Agents; Cell Line; Computer Simulation; Electrocardiography; Fata | 2010 |
A case of long QT syndrome with triple gene abnormalities: digenic mutations in KCNH2 and SCN5A and gene variant in KCNE1.
Topics: Child; DNA Mutational Analysis; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium | 2013 |
A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y.
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Black or African American; Case-Control Studies | 2006 |